Design and synthesis of 3, 5- hetero diesters of 4-deoxy quinic acid and their aphicidal activity against Acyrthosiphon pisum
Résumé
our analogs of 3,5-dicaffeoylquinic acid, including a new heterodiester of 4-deoxyquinic acid, were found toxic against the pea aphid. Several 4-deoxy quinic analogs featuring two different hydroxyl cinnamoyl moieties in position 3 and 5 were prepared for the first time and carefully analysed. Through an assay on pea aphid nymphs, interesting indications on the structure-aphicidal activity relationships and higher levels of toxicity were observed for four compounds related to the reference natural compound.
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