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7-ketocholesterol and 7β-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity

Anne Vejux , Dehbia Abed-Vieillard , Khadija Hajji , Amira Zarrouk , John Mackrill , et al.
Biochemical Pharmacology, 2020, 173, pp.113648. ⟨10.1016/j.bcp.2019.113648⟩
Article dans une revue hal-02308654v1
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Cytoprotective activities of milk thistle seed oil used in traditional tunisian medicine on 7-ketocholesterol and 24s-hydroxycholesterol-induced toxicity on 158n murine oligodendrocytes

Wiem Meddeb , Leila Rezig , Amira Zarrouk , Thomas Nury , Anne Vejux , et al.
Antioxidants , 2018, 7 (7), pp.95. ⟨10.3390/antiox7070095⟩
Article dans une revue hal-02621118v1
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Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases

Leila Rezig , Lucy Martine , Thomas Nury , Kamel Msaada , Nesrine Mahfoudhi , et al.
Journal of oleo science, 2022, 71 (8), pp.1117-1133. ⟨10.5650/jos.ess22110⟩
Article dans une revue hal-03749395v1
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Microgliosis: a double‐edged sword in the control of food intake

Juliette Salvi , Pierre Andreoletti , Etienne Audinat , Eglantine Balland , Selma Ben Fradj , et al.
FEBS Journal, 2024, 291 (4), pp.615-631. ⟨10.1111/febs.16583⟩
Article dans une revue hal-03739689v1

7-ketocholesterol- and 7β-hydroxycholesterol-induced peroxisomal disorders in glial, microglial and neuronal cells: Potential role in neurodegeneration

Thomas Nury , Aline Yammine , Franck Menetrier , Amira Zarrouk , Anne Vejux , et al.
Gérard Lizard. Peroxisome Biology: Experimental Models, Peroxisomal Disorders and Neurological Diseases, 1299, Springer International Publishing, 2020, Advances in Experimental Medicine and Biology (AEMB), 978-3-030-60203-1 (print). ⟨10.1007/978-3-030-60204-8_3⟩
Chapitre d'ouvrage hal-03158086v1

7-Ketocholesterol effects on survival and growth in Drosophila melanogaster

Dehbia Abed-Vieillard , Serge Loquin , William J. Griffiths , Haithem Hamdoun , Anne Vejux , et al.
10. European Network for Oxysterol Research (ENOR) symposium, Sep 2021, Virtual meeting, France
Communication dans un congrès hal-03448141v1

Peroxisomal ABC transporters and X-linked adrenoleukodystrophy

Flore Geillon , Doriane Trompier , Catherine Gondcaille , Gérard Lizard , Stéphane Savary
Médecine/Sciences, 2012, 28 (12), pp.1087-1094. ⟨10.1051/medsci/20122812019⟩
Article dans une revue hal-01221377v1
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P-glycoprotein 1 affects chemoactivities of resveratrol against human colorectal cancer cells

Virginie Aires , Didier J. Colin , Agnès Doreau , Attilio Di Pietro , Jean-Marie Heydel , et al.
Nutrients, 2019, 11 (9), pp.2098. ⟨10.3390/nu11092098⟩
Article dans une revue hal-02627290v1
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The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Rajeev K. Singla , Ronita De , Thomas Efferth , Bruno Mezzetti , M. D. Sahab Uddin , et al.
Phytomedicine, 2022, 108, pp.154520. ⟨10.1016/j.phymed.2022.154520⟩
Article dans une revue hal-03994795v1
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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Meryam Debbabi , Thomas Nury , Amira Zarrouk , Nadia Mekahli , Maryem Bezine , et al.
International Journal of Molecular Sciences, 2016, 17 (12), pp.E1973. ⟨10.3390/ijms17121973⟩
Article dans une revue hal-01463786v1
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Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers

Flore Geillon , Catherine Gondcaille , Soëli Charbonnier , Carlo W. van Roermund , Tatiana E. Lopez , et al.
Journal of Biological Chemistry, 2014, 289 (35), pp.24511-24520. ⟨10.1074/jbc.M114.575506⟩
Article dans une revue hal-01223550v1

Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells

Meryam Debbabi , Amira Zarrouk , Maryem Bezine , Wiem Meddeb , Thomas Nury , et al.
Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.151-170. ⟨10.1016/j.chemphyslip.2017.04.002⟩
Article dans une revue hal-01912331v1
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Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N

Asmaa Badreddine , Amira Zarrouk , El Mostafa Karym , Meryam Debbabi , Thomas Nury , et al.
International Journal of Molecular Sciences, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Article dans une revue hal-01685177v1

Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy

Imen Ghzaiel , Amira Zarrouk , Soukaina Essadek , Lucy Martine , Souha Hammouda , et al.
Steroids, 2022, 183, pp.109032. ⟨10.1016/j.steroids.2022.109032⟩
Article dans une revue hal-03715700v1

Profile of fatty acids, tocopherols, phytosterols and polyphenols in mediterranean oils (argan oils, olive oils, milk thistle seed oils and nigella seed oil) and evaluation of their antioxidant and cytoprotective activities

Amira Zarrouk , Lucy Martine , Stéphane Grégoire , Thomas Nury , Wiem Meddeb , et al.
Current Pharmaceutical Design, 2019, 25 (15), pp.1791-1805. ⟨10.2174/1381612825666190705192902⟩
Article dans une revue hal-02622321v1
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Peroxisomal defects in microglial cells induce a disease-associated microglial signature

Quentin Raas , Ali Tawbeh , Mounia Tahri-Joutey , Catherine Gondcaille , Céline Keime , et al.
Frontiers in Molecular Neuroscience, 2023, 16 (Sec. Brain Disease Mechanisms), pp.1170313. ⟨10.3389/fnmol.2023.1170313⟩
Article dans une revue hal-04092819v1

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol

Thomas Nury , Randa Sghaier , Amira Zarrouk , Franck Menetrier , Tugba Uzun , et al.
Biochimie, 2018, 153, pp.181-202. ⟨10.1016/j.biochi.2018.07.009⟩
Article dans une revue hal-02621805v1

A microglial cell model for acyl-CoA oxidase 1 deficiency

Q. Raas , F-E Saih , C. Gondcaille , D. Trompier , Y. Hamon , et al.
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩
Article dans une revue hal-02359450v1
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Brain Peroxisomes

Doriane Trompier , A. Vejux , A. Zarrouk , Catherine Gondcaille , Flore Geillon , et al.
Biochimie, 2013, 98, pp.102-110. ⟨10.1016/j.biochi.2013.09.009⟩
Article dans une revue hal-01185043v1
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Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation

Ali Tawbeh , Quentin Raas , Mounia Tahri-Joutey , Céline Keime , Romain Kaiser , et al.
Frontiers in Molecular Neuroscience, 2023, 16, pp.1299314. ⟨10.3389/fnmol.2023.1299314⟩
Article dans une revue hal-04352894v1
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Antioxidant properties and cytoprotective effect of pistacia lentiscus l. Seed oil against 7β-hydroxycholesterol-induced toxicity in c2c12 myoblasts: Reduction in oxidative stress, mitochondrial and peroxisomal dysfunctions and attenuation of cell death

Imen Ghzaiel , Amira Zarrouk , Thomas Nury , Michela Libergoli , Francesca Florio , et al.
Antioxidants , 2021, 10 (11), pp.1772. ⟨10.3390/antiox10111772⟩
Article dans une revue hal-03443580v1

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy

Q. Raas , C. Gondcaille , Y. Hamon , V. Leoni , C. Caccia , et al.
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (5), pp.704-714. ⟨10.1016/j.bbalip.2019.02.006⟩
Article dans une revue hal-02359446v1
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Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols

Anne Vejux , Thomas Montange , Lucy Martine , Amira Zarrouk , Jean-Marc Riedinger , et al.
Journal of Agricultural and Food Chemistry, 2012, 60 (16), pp.4060-4066. ⟨10.1021/jf300487r⟩
Article dans une revue hal-01594323v1

A high-fat diet increases l-carnitine synthesis through a differential maturation of the Bbox1 mRNAs.

Caroline Rigault , Françoise Le Borgne , Bassim Tazir , Alexandre Benani , Jean Demarquoy
BBA - Biochimica et Biophysica Acta, 2013, 1831 (2), pp.370-7. ⟨10.1016/j.bbalip.2012.10.007⟩
Article dans une revue istex hal-00787886v1
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Taurine-Conjugated Mussel-Inspired Iron Oxide Nanoparticles with an Elongated Shape for Effective Delivery of Doxorubicin into the Tumor Cells

Nimisha Singh , Nadine Millot , Lionel Maurizi , Gérard Lizard , Rajender Kumar
ACS Omega, 2020, 5 (26), pp.16165-16175. ⟨10.1021/acsomega.0c01747⟩
Article dans une revue hal-02902885v1
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel Klionsky , Amal Kamal Abdel-Aziz , Sara Abdelfatah , Mahmoud Abdellatif , Asghar Abdoli , et al.
Autophagy, 2021, 17 (1), pp.1-382. ⟨10.1080/15548627.2020.1797280⟩
Article dans une revue inserm-03285572v1
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Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in Acox1−/− and Wild-Type BV-2 Microglial Cells

Soukaina Essadek , Catherine Gondcaille , Stéphane Savary , Mohammad Samadi , Joseph Vamecq , et al.
Antioxidants , 2023, 12 (1), pp.168. ⟨10.3390/antiox12010168⟩
Article dans une revue hal-03994321v1