A. A. Spector, Essentiality of fatty acids, Lipids, vol.39, issue.S1, pp.1-3, 1999.
DOI : 10.1007/BF02562220

T. Aki, Y. Shimada, K. Inagaki, H. Higashimoto, S. Kawamoto et al., Molecular Cloning and Functional Characterization of Rat ??-6 Fatty Acid Desaturase, Biochemical and Biophysical Research Communications, vol.255, issue.3, pp.575-579, 1999.
DOI : 10.1006/bbrc.1999.0235

H. P. Cho, M. Nakamura, and S. D. Clarke, Cloning, Expression, and Fatty Acid Regulation of the Human ??-5 Desaturase, Journal of Biological Chemistry, vol.274, issue.52, pp.37335-37339, 1999.
DOI : 10.1074/jbc.274.52.37335

H. P. Cho, M. Nakamura, and S. D. Clarke, Cloning, Expression, and Nutritional Regulation of the Mammalian ??-6 Desaturase, Journal of Biological Chemistry, vol.274, issue.1, 1999.
DOI : 10.1074/jbc.274.1.471

T. Matsuzaka, H. Shimano, N. Yahagi, M. Amemiya-kudo, T. Yoshikawa et al., Dual regulation of mouse 5-and 6-desaturase gene expression by SREBP-1 and PPAR, J. Lipid Res, vol.43, pp.107-114, 2002.

A. Marquardt, H. Stöhr, K. White, and B. H. Weber, cDNA Cloning, Genomic Structure, and Chromosomal Localization of Three Members of the Human Fatty Acid Desaturase Family, Genomics, vol.66, issue.2, pp.175-183, 2000.
DOI : 10.1006/geno.2000.6196

G. Malerba, L. Schaeffer, L. Xumerle, N. Klopp, E. Trabetti et al., SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease, Lipids, vol.13, issue.4, pp.289-299, 2008.
DOI : 10.1007/s11745-008-3158-5

T. Tanaka, J. Shen, G. R. Abecasis, A. Kisialiou, J. M. Ordovas et al., Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study, PLoS Genetics, vol.16, issue.1, p.1000338, 2009.
DOI : 10.1371/journal.pgen.1000338.s004

Y. S. Aulchenko, S. Ripatti, I. Lindqvist, D. Boomsma, I. M. Heid et al., Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts, Nature Genetics, vol.67, issue.1, pp.47-55, 2009.
DOI : 10.1126/science.1142382

S. Kathiresan, C. J. Willer, G. M. Peloso, S. Demissie, K. Musunuru et al., Common variants at 30 loci contribute to polygenic dyslipidemia, Nature Genetics, vol.285, issue.1, pp.56-65, 2009.
DOI : 10.1002/ajmg.1320140315

X. H. Ma, S. J. Hu, H. Ni, Y. C. Zhao, Z. Tian et al., Serial Analysis of Gene Expression in Mouse Uterus at the Implantation Site, Journal of Biological Chemistry, vol.281, issue.14, pp.9351-9360, 2006.
DOI : 10.1074/jbc.M511512200

T. Tondreau, M. Dejeneffe, N. Meuleman, B. Stamatopoulos, A. Delforge et al., Gene expression pattern of functional neuronal cells derived from human bone marrow mesenchymal stromal cells, BMC Genomics, vol.9, issue.1, pp.166-176, 2008.
DOI : 10.1186/1471-2164-9-166

W. J. Park, K. S. Kothapalli, H. T. Reardon, L. Y. Kim, and J. T. Brenna, Novel fatty acid desaturase 3 (FADS3) transcripts generated by alternative splicing, Gene, vol.446, issue.1, pp.28-34, 2009.
DOI : 10.1016/j.gene.2009.06.016

H. Guillou, S. D-'andréa, V. Rioux, R. Barnouin, S. Dalaine et al., Distinct roles of endoplasmic reticulum cytochrome b5 and fused cytochrome b5-like domain for rat ??6-desaturase activity, The Journal of Lipid Research, vol.45, issue.1, pp.32-40, 2004.
DOI : 10.1194/jlr.M300339-JLR200

C. K. Stroud, T. Y. Nara, M. Roqueta-rivera, E. C. Radlowski, P. Lawrence et al., Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration, The Journal of Lipid Research, vol.50, issue.9, pp.1870-1880, 2009.
DOI : 10.1194/jlr.M900039-JLR200

W. Stoffel, B. Holz, B. Jenke, E. Binczek, R. H. Günter et al., ??6-Desaturase (FADS2) deficiency unveils the role of ??3- and ??6-polyunsaturated fatty acids, The EMBO Journal, vol.47, issue.17, pp.2281-2292, 2008.
DOI : 10.1038/emboj.2008.156

D. 'andrea, S. , H. Guillou, S. Jan, D. Catheline et al., The same rat ??6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis, Biochemical Journal, vol.364, issue.1, pp.49-55, 2002.
DOI : 10.1042/bj3640049

H. Guillou, V. Rioux, D. Catheline, J. Thibault, M. Bouriel et al., Conversion of hexadecanoic acid to hexadecenoic acid by rat Delta6-desaturase, The Journal of Lipid Research, vol.44, issue.3, pp.450-454, 2003.
DOI : 10.1194/jlr.C200019-JLR200

W. J. Park, K. S. Kothapalli, P. Lawrence, C. Tyburczy, and J. T. Brenna, An alternate pathway to long chain polyunsaturates: the FADS2 gene product 8-desaturates, pp.2-63, 2009.

C. Ramakers, J. M. Ruijter, R. H. Deprez, and A. F. Moorman, Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data, Neuroscience Letters, vol.339, issue.1, pp.62-66, 2003.
DOI : 10.1016/S0304-3940(02)01423-4

T. Iwamura, M. Yoneyama, K. Yamaguchi, W. Suhara, W. Mori et al., Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways, Genes to Cells, vol.120, issue.4, pp.375-388, 2001.
DOI : 10.1074/jbc.272.22.14434

R. Development and C. Team, R: a language and environment for statistical computing. R Foundation for Statistical Computing, 2008.

T. Saether, T. N. Tran, H. Rootwelt, B. O. Christophersen, and T. B. Haugen, Expression and Regulation of ??5-Desaturase, ??6-Desaturase, Stearoyl-Coenzyme A (CoA) Desaturase 1, and Stearoyl-CoA Desaturase 2 in Rat Testis, Biology of Reproduction, vol.69, issue.1, pp.117-124, 2003.
DOI : 10.1095/biolreprod.102.014035

R. Zolfaghari, C. J. Cefelli, M. D. Banta, and C. Ross, Fatty Acid ??5-Desaturase mRNA Is Regulated by Dietary Vitamin A and Exogenous Retinoic Acid in Liver of Adult Rats, Archives of Biochemistry and Biophysics, vol.391, issue.1, pp.8-15, 2001.
DOI : 10.1006/abbi.2001.2361

G. L. Vilas, M. M. Corvi, G. J. Plummer, A. M. Seime, G. R. Lambkin et al., Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events, Proc. Natl. Acad. Sci. USA, pp.6542-6547, 2006.
DOI : 10.1073/pnas.0600824103

C. Touriol, S. Bornes, S. Bonnal, S. Audigier, H. Prats et al., Generation of protein isoform diversity by alternative initiation of translation at non-AUG codons, Biology of the Cell, vol.95, issue.3-4, pp.169-178, 2003.
DOI : 10.1016/S0248-4900(03)00033-9