Intestinal epithelial cells: regulators of barrier function and immune homeostasis, Nat Rev Immunol, vol.14, pp.141-53, 2014. ,
Diet in the pathogenesis and treatment of inflammatory bowel diseases, Gastroenterology, vol.148, pp.1087-106, 2015. ,
Protein absorption and ammonia production: the effects of dietary protein and removal of the colon, Br J Nutr, vol.35, pp.61-66, 1976. ,
Does digestibility of meat protein help explain large bowel cancer risk?, Nutr Cancer, vol.24, pp.279-88, 1995. ,
Effects of meat cooking, and of ingested amount, on protein digestion speed and entry of residual proteins into the colon: a study in minipigs, PLoS One, vol.8, p.61252, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01547489
Highprotein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health, Am J Clin Nutr, vol.93, pp.1062-72, 2011. ,
High-protein diet modifies colonic microbiota and luminal environment but not colonocyte metabolism in the rat model: the increased luminal bulk connection, Am J Physiol Gastrointest Liver Physiol, vol.307, pp.459-70, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-01173417
The Colonic Microbiome and Epithelial Transcriptome Are Altered in Rats Fed a High-Protein Diet Compared with a Normal-Protein Diet, J Nutr, vol.146, pp.474-83, 2016. ,
Influence of dietary protein supplements on the formation of bacterial metabolites in the colon, Gut, vol.41, pp.70-76, 1997. ,
Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high-protein diet, Am J Physiol Gastrointest Liver Physiol, vol.299, pp.1030-1037, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-01173385
Intestinal luminal nitrogen metabolism: role of the gut microbiota and consequences for the host, Pharmacol Res Off J Ital Pharmacol Soc, vol.68, pp.95-107, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-01001597
Gut microbiota role in dietary protein metabolism and health-related outcomes: the two sides of the coin, Trends Food Sci Technol, vol.57, pp.213-232, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01488443
The deleterious metabolic and genotoxic effects of the bacterial metabolite p-cresol on colonic epithelial cells, Free Radic Biol Med, vol.85, pp.219-246, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01568625
Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide: The adaptive response, Free Radic Biol Med, vol.93, pp.155-64, 2016. ,
URL : https://hal.archives-ouvertes.fr/hal-01568610
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation, Proc Natl Acad Sci, vol.107, pp.228-261, 2010. ,
Commensal Bacteria-Dependent Indole Production Enhances Epithelial Barrier Function in the Colon, PLoS ONE, vol.8, p.80604, 2013. ,
High-protein diet differently modifies intestinal goblet cell characteristics and mucosal cytokine expression in ileum and colon, J Nutr Biochem, vol.26, pp.91-99, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01535233
Fermentable fiber ameliorates fermentable protein-induced changes in microbial ecology, but not the mucosal response, in the colon of piglets, J Nutr, vol.142, pp.661-668, 2012. ,
Down-regulation of monocarboxylate transporter 1 (MCT1) gene expression in the colon of piglets is linked to bacterial protein fermentation and pro-inflammatory cytokine-mediated signalling, Br J Nutr, vol.113, pp.610-617, 2015. ,
Diets high in fermentable protein and fibre alter tight junction protein composition with minor effects on barrier function in piglet colon, Br J Nutr, vol.111, pp.1040-1049, 2014. ,
Modulation of protein fermentation does not affect fecal water toxicity: a randomized cross-over study in healthy subjects, PLoS One, vol.7, p.52387, 2012. ,
High-protein/high red meat and high-carbohydrate weight-loss diets do not differ in their effect on faecal water genotoxicity tested by use of the WIL2-NS cell line and with other biomarkers of bowel health, Mutat Res, vol.703, pp.130-136, 2010. ,
Differential effects of dietary whey, casein and soya on colonic DNA damage and large bowel SCFA in rats fed diets low and high in resistant starch, Br J Nutr, vol.97, pp.535-578, 2007. ,
Interactive Effects of Indigestible Carbohydrates, Protein Type, and Protein Level on Biomarkers of Large Intestine Health in Rats, PLOS ONE, vol.10, p.142176, 2015. ,
Effect of germfree state on the capacities of isolated rat colonocytes to metabolize n-butyrate, glucose, and glutamine, Gastroenterology, vol.109, pp.1890-1899, 1995. ,
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal Biochem, vol.162, pp.156-165, 1987. ,
limma powers differential expression analyses for RNA-sequencing and microarray studies, Nucleic Acids Res, vol.43, p.47, 2015. ,
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing, J R Stat Soc Ser B Methodol, vol.57, pp.289-300, 1995. ,
Metallothioneins in human tumors and potential roles in carcinogenesis, Mutat Res Mol Mech Mutagen, vol.533, pp.201-210, 2003. ,
The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms, Carcinogenesis, vol.32, pp.732-772, 2011. ,
Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin, Proc Natl Acad Sci, vol.78, pp.4515-4524, 1981. ,
Upregulation of miR-136 in human non-small cell lung cancer cells promotes Erk1/2 activation by targeting PPP2R2A, Tumour Biol J Int Soc Oncodevelopmental Biol Med, vol.35, pp.631-671, 2014. ,
Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity, EMBO J, vol.28, pp.1505-1522, 2009. ,
Transcriptome analysis in benefit-risk assessment of micronutrients and bioactive food components, Mol Nutr Food Res, vol.54, pp.240-248, 2010. ,
Utilization of nutrients by isolated epithelial cells of the rat colon, Gastroenterology, vol.83, pp.424-433, 1982. ,
Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer, Drug Metab Rev, vol.47, pp.199-221, 2015. ,
DNA-damage repair; the good, the bad, and the ugly, EMBO J, vol.27, pp.589-605, 2008. ,
Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirements, Gastroenterology, vol.123, pp.50-59, 2002. ,
Heat markers and quality indexes of industrially heat-treated [15 N] milk protein measured in rats, J Agric Food Chem, vol.54, pp.1508-1525, 2006. ,
Nutritional and physiologic significance of human milk proteins, Am J Clin Nutr, vol.77, pp.1537-1580, 2003. ,
Role of NF-?B in epithelial biology, Immunol Rev, vol.246, pp.346-58, 2012. ,
The gastrointestinal mucus system in health and disease, Nat Rev Gastroenterol Hepatol, vol.10, pp.352-61, 2013. ,
Antimicrobial Human ?-Defensins in the Colon and Their Role in Infectious and Non-Infectious Diseases, Pathogens, vol.2, pp.177-92, 2013. ,
Colonic MUC2 mucin regulates the expression and antimicrobial activity of ?-defensin 2, Mucosal Immunol, vol.8, pp.1360-72, 2015. ,
Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial, BMC Med Genet, vol.16, pp.154-158, 2015. ,
Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity, BMC Genomics, vol.13, p.1, 2012. ,
Adaptative increase of ornithine production and decrease of ammonia metabolism in rat colonocytes after hyperproteic diet ingestion, AJP Gastrointest Liver Physiol, vol.287, pp.344-51, 2004. ,
Role of Glutathione in Cancer Progression and Chemoresistance, Oxid Med Cell Longev, p.972913, 2013. ,