J. A. Ainsa, H. D. Parry, and K. F. Chater, A response regulator-like protein that functions at an intermediate stage of sporulation in Streptomyces coelicolor A3(2), Molecular Microbiology, vol.14, issue.3, pp.607-619, 1999.
DOI : 10.1016/0378-1119(92)90669-G

S. F. Altschul, T. L. Madden, A. A. Schäffer, J. Zhang, Z. Zhang et al., Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Research, vol.25, issue.17, pp.3389-3402, 1997.
DOI : 10.1093/nar/25.17.3389

L. A. Becker, M. S. Cetin, R. W. Hutkins, and A. K. Benson, Identification of the gene encoding the alternative sigma factor B from Listeria monocytogenes and its role in osmotolerance, J. Bacteriol, vol.180, pp.4547-4554, 1998.

. Shao, The complete genome sequence of Escherichia coli K-12, Science, vol.277, pp.1453-1474, 1997.

C. J. Bruton, K. A. Plaskitt, and K. F. Chater, Tissue-specific glycogen branching isoenzymes in a multicellular prokaryote, Streptomyces coelicolor A3(2), Streptomyces coelicolor A3, pp.89-99, 1995.
DOI : 10.1111/j.1365-2958.1995.mmi_18010089.x

K. F. Chater, C. J. Bruton, K. A. Plaskitt, M. J. Buttner, C. Méndez et al., The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility ?? factor of B. subtilis, Cell, vol.59, issue.1, pp.133-143, 1989.
DOI : 10.1016/0092-8674(89)90876-3

Y. H. Cho, E. J. Lee, B. E. Ahn, and J. H. Roe, SigB, an RNA polymerase sigma factor required for osmoprotection and proper differentiation of Streptomyces coelicolor, Molecular Microbiology, vol.178, issue.1, pp.205-214, 2001.
DOI : 10.1128/jb.178.20.6036-6042.1996

. Barrell, Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence, Nature, vol.393, pp.537-544, 1998.

K. A. Datsenko and B. L. Wanner, One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products, Proc. Natl. Acad. Sci. USA, pp.6640-6645, 2000.
DOI : 10.1093/nar/27.2.389

G. A. Evans, K. Lewis, and B. E. Rothenberg, High efficiency vectors for cosmid microcloning and genomic analysis, Gene, vol.79, issue.1, pp.9-20, 1989.
DOI : 10.1016/0378-1119(89)90088-7

A. Farewell, K. Kvint, and T. Nystrom, Negative regulation by RpoS: a case of sigma factor competition, Molecular Microbiology, vol.174, issue.4, pp.1039-1051, 1998.
DOI : 10.1128/jb.174.15.5005-5012.1992

G. Fischer, T. Wenner, B. Decaris, and P. Leblond, Chromosomal arm replacement generates a high level of intraspecific polymorphism in the terminal inverted repeats of the linear chromosomal DNA of Streptomyces ambofaciens, Proc. Natl. Acad. Sci. USA 95, pp.14296-14301, 1998.
DOI : 10.1016/S0959-437X(97)80046-9

URL : https://hal.archives-ouvertes.fr/hal-01625341

A. Force, M. Lynch, F. B. Pickett, A. Amores, Y. L. Yan et al., Preservation of duplicate genes by complementary, degenerative mutations, Genetics, vol.151, pp.1531-1545, 1999.

B. Gust, G. L. Challis, K. Fowler, T. Kieser, and K. F. Chater, PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin, Proc. Natl. Acad. Sci. USA, pp.1541-1546, 2003.
DOI : 10.1126/science.277.5333.1820

M. Hecker, W. Schumann, and U. Volker, Heat-shock and general stress response in Bacillus subtilis, Molecular Microbiology, vol.19, issue.3, pp.417-428, 1996.
DOI : 10.1046/j.1365-2958.1996.396932.x

R. Hengge-aronis, Interplay of global regulators and cell physiology in the general stress response of Escherichia coli, Current Opinion in Microbiology, vol.2, issue.2, pp.148-152, 1999.
DOI : 10.1016/S1369-5274(99)80026-5

X. Huang, K. L. Fredrick, and J. D. Helmann, Promoter recognition by Bacillus subtilis W : autoregulation and partial overlap with the X regulon, J. Bacteriol, vol.180, pp.3765-3770, 1998.

R. Hütter, Classification of the streptomycetes with special regard to the antibiotics formed from them, Bibl. Microbiol, vol.6, pp.1-382, 1967.

H. Ikeda, J. Ishikawa, A. Hanamoto, M. Shinose, H. Kikuchi et al., Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis, Nature Biotechnology, vol.21, issue.5, pp.526-531, 2003.
DOI : 10.1038/nbt820

F. Kato, T. Hino, A. Nakaji, M. Tanaka, and Y. Koyama, Carotenoid synthesis in Streptomyces setonii ISP5395 is induced by the gene crtS, whose product is similar to a sigma factor, MGG Molecular & General Genetics, vol.133, issue.3, pp.387-390, 1995.
DOI : 10.1007/BF00293207

F. Kunst, N. Ogasawara, I. Moszer, A. M. Albertini, G. Alloni et al., The complete genome sequence of the grampositive bacterium Bacillus subtilis, Nature, vol.141, issue.6657, pp.249-256, 1997.
DOI : 10.1099/13500872-141-2-261

P. Leblond, P. Demuyter, J. M. Simonet, and B. Decaris, Genetic instability and associated genome plasticity in Streptomyces ambofaciens: pulsed-field gel electrophoresis evidence for large DNA alterations in a limited genomic region., Journal of Bacteriology, vol.173, issue.13, pp.4229-4233, 1991.
DOI : 10.1128/jb.173.13.4229-4233.1991

P. Leblond, G. Fischer, F. X. Francou, F. Berger, M. Guérineau et al., The unstable region of Streptomyces ambofaciens includes 210 kb terminal inverted repeats flanking the extremities of the linear chromosomal DNA, Molecular Microbiology, vol.19, issue.2, pp.261-271, 1996.
DOI : 10.1046/j.1365-2958.1996.366894.x

URL : https://hal.archives-ouvertes.fr/hal-01658762

M. Lonetto, M. Gribskov, and C. A. Gross, The sigma 70 family: sequence conservation and evolutionary relationships., Journal of Bacteriology, vol.174, issue.12, pp.3843-3849, 1992.
DOI : 10.1128/jb.174.12.3843-3849.1992

D. J. Macneil, Characterization of a unique methyl-specific restriction system in Streptomyces avermitilis., Journal of Bacteriology, vol.170, issue.12, pp.5607-5612, 1988.
DOI : 10.1128/jb.170.12.5607-5612.1988

O. Connor, T. J. , P. Kanellis, and J. R. , The ramC gene is required for morphogenesis in Streptomyces coelicolor and expressed in a cell type-specific manner under the direct control of RamR, Molecular Microbiology, vol.141, issue.1, pp.45-57, 2002.
DOI : 10.1016/0378-1119(92)90669-G

M. S. Paget, V. Molle, G. Cohen, Y. Aharonowitz, and M. J. Buttner, Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon, Molecular Microbiology, vol.87, issue.4, pp.1007-1020, 2001.
DOI : 10.1126/science.279.5357.1718

URL : https://hal.archives-ouvertes.fr/hal-00314425

X. Pang, B. Aigle, J. M. Girardet, S. Mangenot, J. L. Pernodet et al., Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome, Antimicrobial Agents and Chemotherapy, vol.48, issue.2, pp.575-588, 2004.
DOI : 10.1128/AAC.48.2.575-588.2004

URL : https://hal.archives-ouvertes.fr/hal-01659031

S. Pinnert-sindico, L. Ninet, J. Preud-'homme, and C. Cosar, A new antibiotic: spiramycin, Antibiot. Annu, pp.724-757, 1954.

L. Potuckova, G. H. Kelemen, K. C. Findlay, M. A. Lonetto, M. J. Buttner et al., is required for the late stages of morphological differentiation in Streptomyces spp., Molecular Microbiology, vol.17, issue.1, pp.37-48, 1995.
DOI : 10.1111/j.1365-2958.1995.mmi_17010037.x

C. Ray, R. E. Hay, H. L. Carter, C. P. Moran, and J. , Mutations that affect utilization of a promoter in stationary-phase Bacillus subtilis, J. Bacteriol, vol.163, pp.610-614, 1985.

J. Sambrook, E. F. Fritsch, and T. Maniatis, Molecular cloning: a laboratory manual, 1989.

B. Sevcikova, O. Benada, O. Kofronova, and J. Kormanec, Stressresponse sigma factor sigma(H) is essential for morphological differentiation of Streptomyces coelicolor, Arch. Microbiol, vol.3, issue.177, pp.98-106, 2001.

W. R. Strohl, Compilation and analysis of DNA sequences associated with apparent streptomycete promoters, Nucleic Acids Research, vol.20, issue.5, pp.961-974, 1992.
DOI : 10.1093/nar/20.5.961

H. Takano, K. Hosono, T. Beppu, and K. Ueda, Involvement of ??H and related sigma factors in glucose-dependent initiation of morphological and physiological development of Streptomyces griseus, Gene, vol.320, pp.127-135, 2003.
DOI : 10.1016/S0378-1119(03)00818-7

H. Tan and K. F. Chater, Two developmentally controlled promoters of Streptomyces coelicolor A3(2) that resemble the major class of motility-related promoters in other bacteria., Journal of Bacteriology, vol.175, issue.4, pp.933-940, 1993.
DOI : 10.1128/jb.175.4.933-940.1993

K. M. Tatti, C. P. Moran, and J. , Promoter recognition by sigma-37 RNA polymerase from Bacillus subtilis, Journal of Molecular Biology, vol.175, issue.3, pp.285-297, 1984.
DOI : 10.1016/0022-2836(84)90349-8

P. H. Viollier, G. H. Kelemen, G. E. Dale, K. T. Nguyen, M. J. Buttner et al., Specialized osmotic stress response systems involve multiple SigB-like sigma factors in Streptomyces coelicolor, Molecular Microbiology, vol.313, issue.417, pp.699-714, 2003.
DOI : 10.1128/jb.173.12.3831-3845.1991

P. H. Viollier, A. Weihofen, M. Folcher, and C. J. Thompson, Post-transcriptional Regulation of the Streptomyces coelicolor Stress Responsive Sigma Factor, SigH, Involves Translational Control, Proteolytic Processing, and an Anti-sigma Factor Homolog, Journal of Molecular Biology, vol.325, issue.4, pp.637-649, 2003.
DOI : 10.1016/S0022-2836(02)01280-9