, Saisine n°2010-SA-0225. https://www.anses.fr/sites

P. Berge, J. Ratel, A. Fournier, C. Jondreville, C. Feidt et al., Use of Volatile Compound Metabolic Signatures in Poultry Liver to Back-Trace Dietary Exposure to Rapidly Metabolized Xenobiotics, Environmental Science & Technology, vol.45, issue.15, pp.6584-6591, 2011.
DOI : 10.1021/es200747h

URL : https://hal.archives-ouvertes.fr/hal-01019411

J. Bouhlel, J. Ratel, S. Abouelkaram, F. Mercier, A. Travel et al.,

E. Engel, Solid-phase microextraction set-up for the analysis of liver volatolome to detect livestock exposure to micropollutants, Journal of Chromatography A, vol.1497, pp.9-18, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01534891

R. Cariou, A. Vénisseau, G. Amand, P. Marchand, M. Marcon et al., Identification de sources de retardateurs de flamme bromés en élevage, Journées de la Recherche Avicole et Palmipèdes à Foie Gras, pp.25-26, 2015.

A. Covaci, L. Roosens, A. C. Dirtu, N. Waegeneers, I. Van-overmeire et al., Brominated flame retardants in Belgian home-produced eggs: Levels and contamination sources, Science of The Total Environment, vol.407, issue.15, pp.4387-4396, 2009.
DOI : 10.1016/j.scitotenv.2008.09.057

, Bilan des plans de surveillance et de contrôle mis en oeuvre par la Direction Générale de l'Alimentation entre, DGAL, 2008.

G. Dervilly-pinel, T. Guérin, B. Minvielle, A. Travel, J. Normand et al., Micropollutants and chemical residues in organic and conventional meat, Food Chemistry, vol.232, pp.218-228, 2017.
DOI : 10.1016/j.foodchem.2017.04.013

URL : https://hal.archives-ouvertes.fr/hal-01534844

E. Dominguez-romero, R. Cariou, E. Omer, P. Marchand, G. Dervilly-pinel et al., ), Journal of Agricultural and Food Chemistry, vol.64, issue.10, pp.2112-2119, 2016.
DOI : 10.1021/acs.jafc.5b05574

M. M. Du, L. F. Lin, C. Z. Yan, and X. Zhang, ), Environmental Science & Technology, vol.46, issue.20, pp.11040-11046, 2012.
DOI : 10.1021/es302166p

, Background document for hexabromocyclododecane and all major diastereomers identified (HBCDD), ECHA (European Chemicals Agency), 2009.

E. Engel, J. Ratel, J. Bouhlel, C. Planche, and M. Meurillon, Novel approaches to improving the chemical safety of the meat chain towards toxicants, Meat Science, vol.109, pp.75-85, 2015.
DOI : 10.1016/j.meatsci.2015.05.016

URL : https://hal.archives-ouvertes.fr/hal-01269251

E. and 2. , Scientific Opinion on Hexabromocyclododecanes (HBCDDs) in Food, EFSA Journal, vol.9, p.2296

E. and 2. , Scientific Opinion on Polybrominated Diphenyl Ethers (PBDEs) in Food, EFSA Journal, vol.95, p.2156

E. Canada and S. Canada, Rapport d'évaluation préalable sur l'hexabromocyclododécane, novembre, 2011.

J. Folch, M. Lees, and G. H. Slaone-stanley, A simple method for the isolation and purification of total lipids from animal tissues, J. Biol. Chem, vol.226, pp.497-509, 1957.

A. Fournier, C. Feidt, M. Dziurla, C. Gandclaudon, and C. Jondreville, Transfer kinetics to egg yolk and modeling residue recovered in yolk of readily metabolized molecules: Polycyclic aromatic hydrocarbons orally administered to laying hens, Chemosphere, vol.78, issue.8, pp.1004-1010, 2010.
DOI : 10.1016/j.chemosphere.2009.12.008

A. Fournier, C. Feidt, P. Marchand, A. Venisseau, L. Bizec et al., Kinetic study of ??-hexabromocyclododecane orally given to laying hens (Gallus domesticus), Environmental Science and Pollution Research, vol.39, issue.2, pp.440-447, 2012.
DOI : 10.1021/es049209t

J. Hiebl and W. Vetter, Detection of Hexabromocyclododecane and Its Metabolite Pentabromocyclododecene in Chicken Egg and Fish from the Official Food Control, Journal of Agricultural and Food Chemistry, vol.55, issue.9, pp.3319-3324, 2007.
DOI : 10.1021/jf063428b

A. Huneau-salaün, M. Guinebretière, A. Taktak, D. Huonnic, and V. Michel, Furnished cages for laying hens: study of the effects of group size and litter provision on laying location, zootechnical performance and egg quality, animal, vol.77, issue.06, pp.911-917, 2011.
DOI : 10.1093/ps/77.12.1828

A. Huneau-salaün, A. Travel, R. Cariou, L. Balaine, and C. Souchet,

G. Pinel, G. Amand, A. Charpiot, L. Bizec, B. Jondreville et al., Etat des lieux de la contamination des oeufs de consommation par des polluants organiques persistants, les retardateurs de flamme bromés, Journées de la Recherche Avicole et Palmipèdes à Foie Gras, pp.1148-1151, 2015.

A. Huneau-salaün, A. Travel, R. Cariou, L. Balaine, C. Souchet et al., Etat des lieux de la contamination des poulets de chair par des polluants organiques persistants, les retardateurs de flamme bromés, p.12, 2017.

C. Jondreville, A. Fournier, S. Jurjanz, E. Engel, J. Ratel et al., Contamination of poultry products by environmental pollutants, XV European Symposium on the Quality of Eggs and Egg Products, XXI European Symposium on the Quality of Poultry Meat, pp.15-19, 2013.

C. Jondreville, R. Cariou, A. Travel, L. Belhomme, G. Dervilly-pinel et al., Hens can ingest extruded polystyrene in rearing buildings and lay eggs contaminated with hexabromocyclododecane, Chemosphere, vol.186, pp.62-67, 2017.
DOI : 10.1016/j.chemosphere.2017.07.117

URL : https://hal.archives-ouvertes.fr/hal-01644035

C. Jondreville, R. Cariou, B. Méda, E. Dominguez-romero, E. Omer et al., Accumulation of ??-hexabromocyclododecane (??-HBCDD) in tissues of fast- and slow-growing broilers ( Gallus domesticus ), Chemosphere, vol.178, pp.424-431, 2017.
DOI : 10.1016/j.chemosphere.2017.03.064

URL : https://hal.archives-ouvertes.fr/hal-01608139

C. Koch, T. Schmidt-kötters, R. Rupp, and B. Sures, Review of hexabromocyclododecane (HBCD) with a focus on legislation and recent publications concerning toxicokinetics and -dynamics, Environmental Pollution, vol.199, pp.26-34, 2015.
DOI : 10.1016/j.envpol.2015.01.011

P. Marchand, R. Cariou, A. Vénisseau, A. Brosseaud, J. Antignac et al., Predicting PCDD/F and dioxin-like PCB contamination levels in bovine edible tissues from in vivo sampling, Chemosphere, vol.80, issue.6, pp.634-640, 2010.
DOI : 10.1016/j.chemosphere.2010.04.057

C. H. Marvin, G. T. Tomy, J. M. Armitage, J. A. Arnot, L. Mccarty et al., , 2011.

, Hexabromocyclododecane: current understanding of chemistry, environmental fate and toxicology and implications for global management, Env. Sci. Technol, vol.45, pp.8613-8623

D. J. Maclachlan, Physiologically based pharmacokinetic (PBPK) model for residues of lipophilic pesticides in poultry, Food Additives & Contaminants: Part A, vol.334, issue.3, pp.302-314, 2010.
DOI : 10.1113/jphysiol.1983.sp014501

B. Méda, E. Royer, S. Guérin, A. Garcia-de-salazar, E. Dominguez-romero et al., Modélisation générique du devenir d'un retardateur de flamme bromé (HBCD) chez le poulet de chair et le porc, p.12, 2017.

Y. Nys and N. Guyot, Egg formation and chemistry, 2011.
DOI : 10.1533/9780857093912.2.83

, Improving the safety and quality of eggs and egg products. Woodhead publish, pp.83-132

, Bioaccumulation in fish: aqueous and dietary exposure, OECD Guidelines for the Testing of Chemicals, Section 3, OECD, issue.305, 2012.

J. Petrlik, L. Bell, D. Kalmykov, and R. Weber, Brominated flame retardants in eggs ? data from Kazakhstan and Thailand, 37th International Symposium on Halogenated Persistent Organic Pollutants, 2017.

P. Poulin and S. Haddad, Advancing Prediction of Tissue Distribution and Volume of Distribution of Highly Lipophilic Compounds from a Simplified Tissue-Composition-Based Model as a Mechanistic Animal Alternative Method, Journal of Pharmaceutical Sciences, vol.101, issue.6, pp.2250-2261, 2012.
DOI : 10.1002/jps.23090

J. Ratel, F. Mercier, A. E. Karam, S. Cariou, R. Dominguez-romero et al., Relevance of volatile metabolome in animal-derived products to reveal a food chain contamination by hexabromocyclododecane, 61st International Congress of Meat Science and Technology, pp.23-28, 2015.

J. Ratel, C. Planche, F. Mercier, P. Blinet, P. Marchand et al., Liver volatolomics to reveal poultry exposure to ??-hexabromocyclododecane (HBCD), Chemosphere, vol.189, pp.634-642, 2017.
DOI : 10.1016/j.chemosphere.2017.09.074

D. F. Rawn, A. Sadler, S. C. Quade, W. F. Sun, B. P. Lau et al., Brominated flame retardants in Canadian chicken egg yolks, Food Additives & Contaminants: Part A, vol.61, issue.6, pp.807-815, 2011.
DOI : 10.1016/j.scitotenv.2008.11.063

, on the monitoring of traces of brominated flame retardants in food, Official Journal of the European Commission, vol.118, issue.65, pp.39-40, 2014.

G. Riviere, V. Sirot, A. Tard, J. Jean, P. Marchand et al., Food risk assessment for perfluoroalkyl acids and brominated flame retardants in the French population: Results from the second French total diet study, Science of The Total Environment, vol.491, issue.492, pp.491-492, 2014.
DOI : 10.1016/j.scitotenv.2014.01.104

E. Royer, B. Méda, R. Cariou, A. Garcia-de-salazar, S. Guérin et al.,

C. Jondreville, Caractérisation et modélisation de l'accumulation dans la viande de porc d'un contaminant émergent : l'hexabromocyclododécane. 49èmes JRP, 2017.

A. Vénisseau, E. Bichon, A. Brosseaud, E. Lesquin, V. Vaccher et al., Resuts of three years of monitoring plans in France : levels of PBDEs, PBBs, HBCDDs, TBBPA and other emerging/novel brominated flame retardants in food, 8th International Symposium on Flame Retardants, 2017.

J. M. Sanders, G. A. Knudsen, and L. S. Birnbaum, The Fate of ??-Hexabromocyclododecane in Female C57BL/6 Mice, Toxicological Sciences, vol.22, issue.2, pp.251-257, 2013.
DOI : 10.1016/j.tiv.2008.05.006

T. Shimmura, T. Azuma, S. Hirahara, Y. Eguchi, K. Uetake et al., Relation between social order and use of resources in small and large furnished cages for laying hens, British Poultry Science, vol.13, issue.5, pp.516-524, 2008.
DOI : 10.1080/00071660500303206

D. T. Szabo, J. J. Diliberto, H. Hakk, J. K. Huwe, and L. S. Birnbaum, Toxicokinetics of the Flame Retardant Hexabromocyclododecane Gamma: Effect of Dose, Timing, Route, Repeated Exposure, and Metabolism, Toxicological Sciences, vol.39, issue.2, pp.282-293, 2010.
DOI : 10.1021/es049209t

D. T. Szabo, J. J. Diliberto, H. Hakk, J. K. Huwe, and L. S. Birnbaum, Toxicokinetics of the Flame Retardant Hexabromocyclododecane Alpha: Effect of Dose, Timing, Route, Repeated Exposure, and Metabolism, Toxicological Sciences, vol.39, issue.2, pp.234-244, 2011.
DOI : 10.1021/es049209t

X. B. Zheng, J. P. Wu, X. J. Luo, Y. H. Zeng, Y. Z. She et al., Halogenated flame retardants in home-produced eggs from an electronic waste recycling region in South China: Levels, composition profiles, and human dietary exposure assessment, Environment International, vol.45, pp.122-128, 2012.
DOI : 10.1016/j.envint.2012.04.006

, Cet article est publié sous la licence Creative Commons (CC BY-NC-ND 3.0) https