This paper focuses on the feasibility of septage treatment by sludge drying reed beds (SDRB). Different designs and operation conditions of SRDB pilot-scales were tested on system efficiencies such as the top filtration layer (sand or compost) and the organic load (30 and 50 kg SS m2 y1). Results focus on the obtained performances considering sludge characteristics, filtration efficiencies, percolate qualities, and sludge deposit properties. Although results show better filtration efficiency for activated sludge (e.g. SS removal around 98.4%) than for septage (e.g. SS removal around 87.5%), the feasibility of septage treatment with SDRB has been demonstrated with, at 50 kg SS m2 y1 sludge accumulation, and dry matter about 7.9 cm y1 and 70% (summer period), respectively. Further design and operation condition recommendations for SDRB treating septage are proposed.