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Multi-tissue partial volume quantification in multi-contrast MRI using an optimised spectral unmixing approach

Abstract : Multi-tissue partial volume estimation in MRI images is investigated with a viewpoint related to spectral unmixing as used in hyperspectral imaging. The main contribution of this paper is twofold. It firstly proposes a theoretical analysis of the statistical optimality conditions of the proportion estimation problem, which in the context of multi-contrast MRI data acquisition allows to appropriately set the imaging sequence parameters. Secondly, an efficient proportion quantification algorithm based on the minimisation of a penalised least-square criterion incorporating a regularity constraint on the spatial distribution of the proportions is proposed. Furthermore, the resulting developments are discussed using empirical simulations. The practical usefulness of the spectral unmixing approach for partial volume quantification in MRI is illustrated through an application to food analysis on the proving of a Danish pastry.
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https://hal.inrae.fr/hal-02607310
Déposant : Migration Irstea Publications <>
Soumis le : samedi 16 mai 2020 - 14:00:50
Dernière modification le : lundi 18 mai 2020 - 14:38:59

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G. Collewet, Sawsen Moussaoui, C. Deligny, T. Lucas, J. Idier. Multi-tissue partial volume quantification in multi-contrast MRI using an optimised spectral unmixing approach. Magnetic Resonance Imaging, Elsevier, 2018, 49, pp.39-46. ⟨https://doi.org/10.1016/j.mri.2017.12.027⟩. ⟨hal-02607310⟩

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