N. Siriwardhana, N. S. Kalupahana, N. Moustaid-moussa, and K. Se-kwon, Eicosapentaenoic acid and Docosahexaenoic acid, vol.65, pp.211-233, 2012.

M. Plourde and S. C. Cunnane, Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements, Appl Physiol Nutr Metab, vol.32, issue.4, pp.619-653, 2007.

E. J. Baker, E. A. Miles, G. C. Burdge, P. Yaqoob, and P. C. Calder, Metabolism and functional effects of plant-derived omega-3 fatty acids in humans, Prog Lipid Res, vol.64, pp.30-56, 2016.

A. P. Simopoulos, Omega-3 fatty acids in inflammation and autoimmune diseases, J Am Coll Nutr, vol.21, issue.6, pp.495-505, 2002.

R. J. Deckelbaum and C. Torrejon, The omega-3 fatty acid nutritional landscape: health benefits and sources, J Nutr, vol.142, issue.3, pp.587-91, 2012.

P. C. Calder, Functional roles of fatty acids and their effects on human health, J Parenter Enter Nutr, vol.39, issue.1, pp.18-32, 2015.

R. L. Cerri, S. O. Juchem, R. C. Chebel, H. M. Rutigliano, R. G. Bruno et al., Effect of fat source differing in fatty acid profile on metabolic parameters, fertilization, and embryo quality in high-producing dairy cows, J Dairy Sci, vol.92, issue.4, pp.1520-1551, 2009.

J. E. Santos, T. R. Bilby, W. W. Thatcher, C. R. Staples, and F. T. Silvestre, Long chain fatty acids of diet as factors influencing reproduction in cattle, Reprod Domest Anim, vol.43, issue.2, pp.23-30, 2008.

D. J. Ambrose, J. P. Kastelic, R. Corbett, P. A. Pitney, H. V. Petit et al., Lower pregnancy losses in lactating dairy cows fed a diet enriched in alpha-linolenic acid, J Dairy Sci, vol.89, issue.8, pp.3066-74, 2006.

S. Elis, S. Freret, A. Desmarchais, V. Maillard, J. Cognié et al., Effect of a long chain n-3 PUFA-enriched diet on production and reproduction variables in Holstein dairy cows, Anim Reprod Sci, vol.164, pp.121-153, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01512139

E. Dirandeh, A. Towhidi, S. Zeinoaldini, M. Ganjkhanlou, A. Pirsaraei et al., Effects of different polyunsaturated fatty acid supplementations during the postpartum periods of early lactating dairy cows on milk yield, metabolic responses, and reproductive performances, J Anim Sci, vol.91, issue.2, pp.713-734, 2013.

H. V. Petit and H. Twagiramungu, Conception rate and reproductive function of dairy cows fed different fat sources, Theriogenology, vol.66, issue.5, pp.1316-1340, 2006.

U. Moallem, A. Shafran, M. Zachut, I. Dekel, Y. Portnick et al., Dietary alphalinolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil, Reproduction, vol.146, issue.6, pp.603-617, 2013.

M. Zachut, I. Dekel, H. Lehrer, A. Arieli, A. Arav et al., Effects of dietary fats differing in n-6:n-3 ratio fed to high-yielding dairy cows on fatty acid composition of ovarian compartments, follicular status, and oocyte quality, J Dairy Sci, vol.93, issue.2, pp.529-574, 2010.

M. Oseikria, S. Elis, V. Maillard, E. Corbin, and S. Uzbekova, N-3 polyunsaturated fatty acid DHA during IVM affected oocyte developmental competence in cattle, Theriogenology, vol.85, pp.1625-1659, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01409334

N. D. Riediger, R. A. Othman, M. Suh, and M. H. Moghadasian, A systemic review of the roles of n-3 fatty acids in health and disease, J Am Diet Assoc, vol.109, issue.4, pp.668-79, 2009.

P. C. Calder, Mechanisms of action of (n-3) fatty acids, J Nutr, vol.142, issue.3, pp.592-601, 2012.

P. C. Calder, Fatty acids and inflammation: the cutting edge between food and pharma, Eur J Pharmacol, vol.668, issue.1, pp.50-58, 2011.

P. C. Calder, Marine omega-3 fatty acids and inflammatory processes: effects, mechanisms and clinical relevance, Biochim et Biophys Acta (BBA) -Molecular and Cell Biology of Lipids, vol.1851, issue.4, pp.469-84, 2015.

J. Miyamoto, S. Hasegawa, M. Kasubuchi, A. Ichimura, A. Nakajima et al., Nutritional signaling via free fatty acid receptors, Int J Mol Sci, vol.17, issue.4, p.450, 2016.

R. Prihandoko, E. Alvarez-curto, B. D. Hudson, A. J. Butcher, T. Ulven et al., Distinct Phosphorylation clusters determine the signaling outcome of free fatty acid receptor 4/G protein-coupled receptor 120, Mol Pharmacol, vol.89, issue.5, pp.505-525, 2016.

Y. Su, J. M. Denegre, K. Wigglesworth, F. L. Pendola, M. J. O'brien et al., Oocyte-dependent activation of mitogen-activated protein kinase (ERK1/2) in cumulus cells is required for the maturation of the mouse oocytecumulus cell complex, Dev Biol, vol.263, issue.1, pp.126-164, 2003.

S. Uzbekova, M. Salhab, C. Perreau, P. Mermillod, and J. Dupont, Glycogen synthase kinase 3B in bovine oocytes and granulosa cells: possible involvement in meiosis during in vitro maturation, Reproduction, vol.138, issue.2, pp.235-281, 2009.

M. Salhab, L. Tosca, C. Cabau, P. Papillier, C. Perreau et al., Kinetics of gene expression and signaling in bovine cumulus cells throughout IVM in different mediums in relation to oocyte developmental competence, cumulus apoptosis and progesterone secretion, Theriogenology, vol.75, issue.1, pp.90-104, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01129418

B. D. Hudson, B. Shimpukade, A. E. Mackenzie, A. J. Butcher, J. D. Pediani et al., The pharmacology of TUG-891, a potent and selective agonist of the free fatty acid receptor 4 (FFA4/GPR120), demonstrates both potential opportunity and possible challenges to therapeutic agonism, Mol Pharmacol, vol.84, issue.5, pp.710-735, 2013.

. R_core_team, R: a language and environment for statistical computing: Vienna, R-project, 2015.

P. Delmar, S. Robin, and J. J. Daudin, VarMixt: efficient variance modelling for the differential analysis of replicated gene expression data, Bioinformatics, vol.21, issue.4, pp.502-510, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00126119

S. Dudoit, Y. H. Yang, M. J. Callow, and T. P. Speed, Statistical methods for identifying differentially expressed genes in replicated Cdna microarray experiments, Stat Sin, vol.12, issue.1, pp.111-150, 2002.

S. Elis, S. Coyral-castel, S. Freret, J. Cognié, A. Desmarchais et al., Expression of adipokine and lipid metabolism genes in adipose tissue of dairy cows differing in a female fertility quantitative trait locus, J Dairy Sci, vol.96, issue.12, pp.7591-602, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01129783

J. Fox, The R commander: a basic-statistics graphical. User Interface to R, vol.14, p.42, 2005.

R. V. Lenth and M. Hervé, , 2015.

B. Wheeler, lmPerm: permutation tests for linear models, 2010.

F. Konietschke, M. Placzek, F. Schaarschmidt, and L. A. Hothorn, Nparcomp: an R software package for nonparametric multiple comparisons and simultaneous confidence intervals, J Stat Softw, vol.64, issue.9, pp.1-17, 2015.

R. Bosviel, L. Joumard-cubizolles, G. Chinetti-gbaguidi, D. Bayle, C. Copin et al., DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: putative mechanisms through PPAR activation, Free Radic Biol Med, vol.103, pp.146-54, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01594580

X. Chen, Q. Wang, L. Zhan, and A. Shu, Effects and mechanisms of docosahexaenoic acid on the generation of angiopoietin-2 by rat brain microvascular endothelial cells under an oxygen-and glucose-deprivation environment, SpringerPlus, vol.5, issue.1, p.1518, 2016.

J. Gdula-argasi?ska, J. Czepiel, J. Toto?-?ura?ska, P. Wo?kow, T. Librowski et al., N-3 fatty acids regulate the inflammatory-state related genes in the lung epithelial cells exposed to polycyclic aromatic hydrocarbons, Pharm Rep, vol.68, issue.2, pp.319-347, 2016.

M. Todor?evi? and L. Hodson, The effect of marine derived n-3 fatty acids on adipose tissue metabolism and function, Journal of Clinical Medicine, vol.5, issue.1, p.3, 2016.

H. Vaidya and S. K. Cheema, Arachidonic acid has a dominant effect to regulate lipogenic genes in 3T3-L1 adipocytes compared to omega-3 fatty acids, Food Nutr Res, vol.59, 2015.

H. Ji, J. Piao, S. Kim, D. Kim, H. Lee et al., Docosahexaenoic acid inhibits helicobacter pylori-induced STAT3 phosphorylation through activation of PPAR?, Mol Nutr Food Res, vol.60, issue.6, pp.1448-57, 2016.

V. Casañas-sánchez, J. A. Pérez, N. Fabelo, D. Quinto-alemany, and M. L. Díaz, Docosahexaenoic (DHA) modulates phospholipid-hydroperoxide glutathione peroxidase (Gpx4) gene expression to ensure self-protection from oxidative damage in hippocampal cells, Front Physiol, vol.6, p.203, 2015.

S. Elis, A. Desmarchais, S. Freret, V. Maillard, V. Labas et al., Effect of a long-chain n-3 polyunsaturated fatty acidenriched diet on adipose tissue lipid profiles and gene expression in Holstein dairy cows, J Dairy Sci, vol.99, issue.12, pp.10109-10136, 2016.

L. Sanchez-lazo, D. Brisard, S. Elis, V. Maillard, R. Uzbekov et al., Fatty acid synthesis and oxidation in cumulus cells support oocyte maturation in bovine, Mol Endocrinol, vol.28, issue.9, pp.1502-1523, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01129856

M. M. Hopkins, Z. Zhang, Z. Liu, and K. E. Meier, Eicosopentaneoic acid and other free fatty acid receptor agonists inhibit Lysophosphatidic acid-and epidermal growth factor-induced proliferation of human breast cancer cells, Journal of Clinical Medicine, vol.5, issue.2, p.16, 2016.

Z. Liu, M. M. Hopkins, Z. Zhang, C. B. Quisenberry, L. C. Fix et al., Omega-3 fatty acids and other FFA4 agonists inhibit growth factor signaling in human prostate cancer cells, J Pharmacol Exp Ther, vol.352, issue.2, pp.380-94, 2015.

D. Boruszewska, E. Sinderewicz, I. Kowalczyk-zieba, K. Grycmacher, and I. Woclawek-potocka, The effect of lysophosphatidic acid during in vitro maturation of bovine cumulus-oocyte complexes: cumulus expansion, glucose metabolism and expression of genes involved in the ovulatory cascade, oocyte and blastocyst competence, Reprod Biol Endocrinol, vol.13, issue.1, p.44, 2015.

B. Shimpukade, B. D. Hudson, C. K. Hovgaard, G. Milligan, and T. Ulven, Discovery of a potent and selective GPR120 agonist, J Med Chem, vol.55, issue.9, pp.4511-4516, 2012.

T. Song, Y. Zhou, J. Peng, Y. Tao, Y. Yang et al., GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway, Mol Cell Endocrinol, vol.434, pp.1-13, 2016.

A. N. Anbazhagan, S. Priyamvada, T. Gujral, S. Bhattacharyya, W. A. Alrefai et al., A novel anti-inflammatory role of GPR120 in intestinal epithelial cells, Am J Physiol Cell Physiol, vol.310, issue.7, pp.612-633, 2016.

X. Li, L. L. Ballantyne, C. X. Mewburn, J. D. Kang, J. X. Barkley et al., Endogenously generated Omega-3 fatty acids attenuate vascular inflammation and Neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice, Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, vol.4, issue.4, p.1856, 2015.

D. Y. Oh, S. Talukdar, E. J. Bae, T. Imamura, H. Morinaga et al., GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects, Cell, vol.142, issue.5, pp.687-98, 2010.

M. Bhojwani, E. Rudolph, W. Kanitz, H. Zuehlke, F. Schneider et al., Molecular analysis of maturation processes by protein and Phosphoprotein profiling during in vitro maturation of bovine Oocytes: a proteomic approach, Cloning Stem Cells, vol.8, issue.4, pp.259-74, 2006.