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. Comment, J. Pires, K. Pawlowski, J. Rouel, C. Delavaud et al., , 2019.

, Multiparous Holstein cows were either allowed ad libitum intake of a regular diet 658 throughout the study (Control, n = 9), or underwent 4 days of nutrient restriction (Restricted, n = 8) 659 by receiving a ration composed of 48% (DM-basis) straw from 24 to 27 ± 3 DIM (mean ± SD), Dry matter intake (DMI, A), milk yield (B), energy balance (C), and somatic cell count 657 (SCC, D), vol.1

, BHB (B), glucose (C), urea (D) and insulin (E) concentrations, Figure 2. Plasma NEFA (A)

, or underwent 4 days of nutrient restriction (Restricted, n = 8) by receiving a 667 ration composed of 48% (DM-basis) straw from 24 to 27 ± 3 DIM (mean ± SD). One healthy rear 668 mammary quarter was injected with 50 µg of LPS (E. coli 0111:B4) 72 h after initiation of dietary 669 treatments, Multiparous Holstein cows were either allowed ad libitum intake of a regular diet throughout the 666 study (Control, n = 9

, TNF-? (E) and CXCL3 (F) concentrations in response to 673 LPS challenge in early lactation cows. Multiparous Holstein cows were either allowed ad libitum 674 intake of a regular diet throughout the study (Control, n = 9), or underwent 96 h of nutrient 675 restriction (Restricted, n = 8) by receiving a ration composed of 48% (DM-basis) straw from 24 to 676 27 ± 3 DIM (mean ± SD), Effects of nutrient restriction on rectal temperature increment (A), plasma cortisol 672 increment (B), milk Il-8 (C), IL-1? (D)

J. Pawlowski, K. Rouel, J. Delavaud, C. Foucras, G. Germon et al., Rectal temperature was recorded and blood 678 samples collected before and at 1, 2, 4, 6, 10 and 24 h; foremilk milk samples were collected from Comment citer ce document : Pires, coli 0111:B4) 72 h after initiation of dietary treatments, 2019.

, the injected mammary quarter before and at 4, 6, 10 and 24 h relative to LPS administration, Values 680 are LSM ± SEM

, Multiparous Holstein cows were either allowed ad libitum 684 intake of a regular diet throughout the study (Control, n = 9), or underwent 96 h of nutrient 685 restriction (Restricted, n = 8) by receiving a ration composed of 48% (DM-basis) straw from 24 to 686 27 ± 3 DIM (mean ± SD). One healthy rear mammary quarter was

, coli 0111:B4) 72 h after initiation of dietary treatments. Blood samples collected before and at 1, 2, 688 4, 6, 10 and 24 h relative to LPS injection

. Comment, J. Pires, K. Pawlowski, J. Rouel, C. Delavaud et al., , 2019.