GIP and GLP-1, the two incretin hormones: similarities and differences, J Diabetes Investig, vol.1, pp.8-23, 2010. ,
Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors, Endocr Rev, vol.35, pp.992-1019, 2014. ,
CD26/DPP4 levels in peripheral blood and T cells in patients with type 2 diabetes mellitus, J Clin Endocrinol Metab, vol.98, pp.2553-2561, 2013. ,
Obese patients have higher circulating protein levels of dipeptidyl peptidase IV, Peptides, vol.61, pp.75-82, 2014. ,
Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro, Diabetes Care, vol.36, pp.4083-4090, 2013. ,
Sixteen-years of clinically relevant dipeptidyl peptidase-IV (DPP-IV) inhibitors for treatment of type-2 diabetes: a perspective, Curr Med Chem, vol.21, pp.4013-4045, 2014. ,
Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice, Endocrinology, vol.152, pp.3018-3029, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00851695
Cellular sites and mechanisms linking reduction of dipeptidyl peptidase-4 activity to control of incretin hormone action and glucose homeostasis, Cell Metab, vol.25, pp.152-165, 2017. ,
CD26/dipeptidylpeptidase IV-chemokine interactions: doubleedged regulation of inflammation and tumor biology, J Leukoc Biol, vol.99, pp.955-969, 2016. ,
Dipeptidyl peptidase inhibitors, an emerging drug class for inflammatory disease?, Trends Pharmacol Sci, vol.30, pp.600-607, 2009. ,
Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagonlike peptide-2 in rats and mice, Endocrinology, vol.141, pp.4013-4020, 2000. ,
Soluble DPP4 induces inflammation and proliferation of human smooth muscle cells via protease-activated receptor 2, Biochim Biophys Acta, vol.1842, pp.1613-1621, 2014. ,
Soluble DPP-4 up-regulates toll-like receptors and augments inflammatory reactions, which are ameliorated by vildagliptin or mannose-6-phosphate, Metabolism, vol.65, pp.89-101, 2016. ,
Sitagliptin exerts an antinflammatory action, J Clin Endocrinol Metab, vol.97, pp.3333-3341, 2012. ,
DPP-4 (CD26) inhibitor alogliptin inhibits TLR4-mediated ERK activation and ERK-dependent MMP-1 expression by U937 histiocytes, Atherosclerosis, vol.213, pp.429-435, 2010. ,
Anagliptin, a DPP-4 inhibitor, suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction and attenuates atherosclerosis in male apo E-deficient mice, Endocrinology, vol.154, pp.1260-1270, 2013. ,
Innate immunity in the small intestine, Curr Opin Gastroenterol, vol.28, pp.124-129, 2012. ,
Clinical pharmacokinetics and pharmacodynamics of vildagliptin, Clin Pharmacokinet, vol.51, pp.147-162, 2012. ,
Targeting gut microbiota in obesity: effects of prebiotics and probiotics, Nat Rev Endocrinol, vol.7, pp.639-646, 2011. ,
An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice, Gut, vol.63, pp.727-735, 2014. ,
Cloning and functional expression of dipeptidyl peptidase IV from the ruminal bacterium Prevotella albensis M384(T), Microbiology, vol.149, pp.2227-2234, 2003. ,
Characterization of the recombinant exopeptidases PepX and PepN from Lactobacillus helveticus ATCC 12046 important for food protein hydrolysis, PLoS One, vol.8, p.70055, 2013. ,
Purification and characterization of an Xprolyl-dipeptidyl peptidase from Lactobacillus sakei, Appl Environ Microbiol, vol.67, pp.1815-1820, 2001. ,
Bifidobacteria possess inhibitory activity against dipeptidyl peptidase-IV, Lett Appl Microbiol, vol.62, pp.250-255, 2016. ,
Screening for potential novel probiotic Lactobacillus strains based on high dipeptidyl peptidase IV and ?glucosidase inhibitory activity, J Funct Foods, vol.20, pp.486-495 ,
Vildagliptin increases butyrateproducing bacteria in the gut of diabetic rats, PLoS One, vol.12, p.184735, 2017. ,
A specific gut microbiota dysbiosis of type 2 diabetic mice induces GLP-1 resistance through an enteric NO-dependent and gut-brain axis mechanism, Cell Metab, vol.25, p.1075, 2017. ,
Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia, ISME J, vol.10, pp.1456-1470, 2016. ,
Resistant starch can improve insulin sensitivity independently of the gut microbiota, vol.5, p.12, 2017. ,
Inulin-type fructans modulate intestinal Bifidobacterium species populations and decrease fecal short-chain fatty acids in obese women, Clin Nutr, vol.34, pp.501-507, 2015. ,
Spirulina protects against hepatic inflammation in aging: an effect related to the modulation of the gut microbiota, Nutrients, vol.9, 2017. ,
Kupffer cell activity is involved in the hepatoprotective effect of dietary oligofructose in rats with endotoxic shock, J Nutr, vol.134, pp.1124-1129, 2004. ,
Precision-cut liver slices in culture as a tool to assess the physiological involvement of Kupffer cells in hepatic metabolism, Comp Hepatol, vol.3, issue.1, p.45, 2004. ,
Fat binding capacity and modulation of the gut microbiota both determine the effect of wheat bran fractions on adiposity, Sci Rep, vol.7, p.5621, 2017. ,
Phylogenetic distribution of three pathways for propionate production within the human gut microbiota, ISME J, vol.8, pp.1323-1335, 2014. ,
Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability, Gut, vol.58, pp.1091-1103, 2009. ,
High fat diet impairs the function of glucagon-like peptide-1 producing L-cells, Peptides, vol.77, pp.21-27, 2016. ,
The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents, Int J Obes, vol.39, pp.424-429, 2015. ,
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface, Proc Natl Acad Sci U S A, vol.105, pp.20858-20863, 2008. ,
Antidiabetic drugs 'gliptins' affect biofilm formation by Streptococcus mutans, Microbiol Res, vol.209, pp.79-85, 2018. ,
Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice, PLoS One, vol.7, p.34233, 2012. ,
Bifidobacterium pseudocatenulatum CECT 7765 reduces obesity-associated inflammation by restoring the lymphocyte-macrophage balance and gut microbiota structure in high-fat diet-fed mice, PLoS One, vol.10, p.126976, 2015. ,
Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptinresistant mice: impact on apelin regulation in adipose tissue, Front Microbiol, vol.2, p.149, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-00617647
The gut barrier: new acquisitions and therapeutic approaches, J Clin Gastroenterol, vol.46, pp.12-17, 2012. ,
Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity, ISME J, vol.8, pp.2116-2130, 2014. ,
Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis, Endocrinology, vol.153, pp.1141-1151, 2012. ,
Induction of intestinal epithelial proliferation by glucagon-like peptide 2, Proc Natl Acad Sci, pp.7911-7916, 1996. ,
Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the diet-induced NASH (DIN) hamster model, Eur J Pharmacol, vol.818, pp.449-456, 2018. ,
Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation, J Pathol, vol.243, pp.431-441, 2017. ,
Pharmacokinetics of dipeptidylpeptidase-4 inhibitors, Diabetes Obes Metab, vol.12, pp.648-658, 2010. ,