D. Hazlerigg and V. Simonneaux, Physiology of reproduction, vol.2, pp.1575-1604, 2014.

R. J. Reiter, Pineal melatonin: cell biology of its synthesis and of its physiological interactions, Endocr Rev, vol.12, pp.151-180, 1991.

T. J. Bartness, J. B. Powers, M. H. Hastings, E. L. Bittman, and B. D. Goldman, The timed infusion paradigm for melatonin delivery: what has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses, Journal of pineal research, vol.15, pp.161-190, 1993.

B. D. Goldman, Mammalian photoperiodic system: formal properties and neuroendocrine mechanisms of photoperiodic time measurement, Journal of biological rhythms, vol.16, pp.283-301, 2001.

S. M. Hiebert, S. A. Green, and S. M. Yellon, Daily timed melatonin feedings mimic effects of short days on testis regression and cortisol in circulation in Siberian hamsters, Gen Comp Endocrinol, vol.146, pp.211-216, 2006.

J. C. Walton, Z. Chen, J. B. Travers, and R. J. Nelson, Exogenous melatonin reproduces the effects of short day lengths on hippocampal function in male white-footed mice, Peromyscus leucopus, Neuroscience, vol.248, pp.403-413, 2013.

R. J. Reiter, The pineal and its hormones in the control of reproduction in mammals, Endocr Rev, vol.1, pp.109-131, 1980.

B. Malpaux, M. Migaud, H. Tricoire, and P. Chemineau, Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin, Journal of biological rhythms, vol.16, pp.336-347, 2001.

C. Zhao, W. Deng, and F. H. Gage, Mechanisms and functional implications of adult neurogenesis, Cell, vol.132, pp.645-660, 2008.

M. Migaud, Emerging new sites for adult neurogenesis in the mammalian brain: a comparative study between the hypothalamus and the classical neurogenic zones. The European journal of neuroscience, vol.32, pp.2042-2052, 2010.
URL : https://hal.archives-ouvertes.fr/hal-01129461

M. Migaud, L. Butrille, and M. Batailler, Seasonal regulation of structural plasticity and neurogenesis in the adult mammalian brain: focus on the sheep hypothalamus, Frontiers in neuroendocrinology, vol.37, pp.146-157, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01154739

D. A. Lee and S. Blackshaw, Functional implications of hypothalamic neurogenesis in the adult mammalian brain, Int J Dev Neurosci, vol.30, pp.615-621, 2012.

E. Rojczyk-golebiewska, A. Palasz, and R. Wiaderkiewicz, Hypothalamic subependymal niche: a novel site of the adult neurogenesis, Cell Mol Neurobiol, vol.34, pp.631-642, 2014.

M. V. Kokoeva, H. Yin, and J. S. Flier, Evidence for constitutive neural cell proliferation in the adult murine hypothalamus, The Journal of comparative neurology, vol.505, pp.209-220, 2007.

D. E. Mcnay, N. Briançon, M. V. Kokoeva, E. Maratos-flier, and J. S. Flier, Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice, J Clin Invest, vol.122, pp.142-152, 2012.

M. Batailler, DCX-expressing cells in the vicinity of the hypothalamic neurogenic niche: a comparative study between mouse, sheep, and human tissues, J Comp Neurol, vol.522, pp.1966-1985, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01129786

M. Migaud, M. Batailler, D. Pillon, I. Franceschini, and B. Malpaux, Seasonal changes in cell proliferation in the adult sheep brain and pars tuberalis, Journal of biological rhythms, vol.26, pp.486-496, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01129544

M. Batailler, L. Derouet, L. Butruille, and M. Migaud, Sensitivity to the photoperiod and potential migratory features of neuroblasts in the adult sheep hypothalamus, Brain structure & function, vol.221, pp.3301-3314, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01406204

A. Chanvallon, New insights into the influence of breed and time of the year on the response of ewes to the 'ram effect, Animal: an international journal of animal bioscience, vol.5, pp.1594-1604, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01129573

L. A. Galea and B. S. Mcewen, Sex and seasonal differences in the rate of cell proliferation in the dentate gyrus of adult wild meadow voles, Neuroscience, vol.89, pp.955-964, 1999.

B. K. Ormerod and L. A. Galea, Reproductive status influences the survival of new cells in the dentate gyrus of adult male meadow voles, Neuroscience letters, vol.346, pp.25-28, 2003.

K. Bartkowska, R. L. Djavadian, J. R. Taylor, and K. Turlejski, Generation recruitment and death of brain cells throughout the life cycle of Sorex shrews (Lipotyphla), Eur J Neurosci, vol.27, pp.1710-1721, 2008.

L. Huang, G. J. Devries, and E. L. Bittman, Photoperiod regulates neuronal bromodeoxyuridine labeling in the brain of a seasonally breeding mammal, Journal of neurobiology, vol.36, pp.410-420, 1998.

M. T. Smith, V. Pencea, Z. Wang, M. B. Luskin, and T. Insel, Increased number of BrdU-labeled neurons in the rostral migratory stream of the estrous prairie vole, Hormones and behavior, vol.39, pp.11-21, 2001.

F. Doetsch, I. Caille, D. A. Lim, J. M. Garcia-verdugo, and A. Alvarez-buylla, Subventricular zone astrocytes are neural stem cells in the adult mammalian brain, Cell, vol.97, pp.703-716, 1999.

M. V. Kokoeva, H. Yin, and J. S. Flier, Neurogenesis in the hypothalamus of adult mice: potential role in energy balance, Science, vol.310, pp.679-683, 2005.

V. Breton-provencher, M. Lemasson, M. R. Peralta, and A. Iii-&-saghatelyan, Interneurons produced in adulthood are required for the normal functioning of the olfactory bulb network and for the execution of selected olfactory behaviors, J Neurosci, vol.29, pp.15245-15257, 2009.

S. Dutheil, J. M. Brezun, J. Leonard, M. Lacour, and B. Tighilet, Neurogenesis and astrogenesis contribution to recovery of vestibular functions in the adult cat following unilateral vestibular neurectomy: cellular and behavioral evidence, Neuroscience, vol.164, pp.1444-1456, 2009.

K. Kozar, Mouse development and cell proliferation in the absence of D-cyclins, Cell, vol.118, pp.477-491, 2004.

D. G. Hazlerigg, C. A. Wyse, H. Dardente, E. A. Hanon, and G. A. Lincoln, Photoperiodic variation in CD45-positive cells and cell proliferation in the mediobasal hypothalamus of the Soay sheep, Chronobiol Int, vol.30, pp.548-558, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01129737

F. Nottebohm, A brain for all seasons: cyclical anatomical changes in song control nuclei of the canary brain, Science, vol.214, pp.1368-1370, 1981.

J. A. Paton and F. N. Nottebohm, Neurons generated in the adult brain are recruited into functional circuits, Science, vol.225, pp.1046-1048, 1984.

D. F. Sherry and J. S. Hoshooley, Seasonal hippocampal plasticity in food-storing birds, Philosophical transactions of the Royal Society of London. Series B, Biological sciences, vol.365, pp.933-943, 2010.

D. K. Burger, J. M. Saucier, A. N. Iwaniuk, and D. M. Saucier, Seasonal and sex differences in the hippocampus of a wild rodent, Behav Brain Res, vol.236, pp.131-138, 2013.

P. Lavenex, M. A. Steele, and L. F. Jacobs, The seasonal pattern of cell proliferation and neuron number in the dentate gyrus of wild adult eastern grey squirrels, Eur J Neurosci, vol.12, pp.643-648, 2000.

J. C. Walton, L. M. Pyter, Z. M. Weil, and R. J. Nelson, Photoperiod mediated changes in olfactory bulb neurogenesis and olfactory behavior in male white-footed mice (Peromyscus leucopus), PLoS One, vol.7, p.42743, 2012.

N. L. Wayne, B. Malpaux, and F. J. Karsch, Photoperiodic requirements for timing onset and duration of the breeding season of the ewe: synchronization of an endogenous rhythm of reproduction, Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, vol.166, pp.835-842, 1990.

, Scientific RePoRtS |, vol.8, p.6188, 2018.

C. J. Woodfill, N. L. Wayne, S. M. Moenter, and F. J. Karsch, Photoperiodic synchronization of a circannual reproductive rhythm in sheep: identification of season-specific time cues, Biology of reproduction, vol.50, pp.965-976, 1994.

J. Chu, Effects of melatonin and its analogues on neural stem cells, Molecular and cellular endocrinology, vol.420, pp.169-179, 2016.

X. Kong, Melatonin regulates the viability and differentiation of rat midbrain neural stem cells, Cell Mol Neurobiol, vol.28, pp.569-579, 2008.

C. Tocharus, Melatonin enhances adult rat hippocampal progenitor cell proliferation via ERK signaling pathway through melatonin receptor, Neuroscience, vol.275, pp.314-321, 2014.

A. Sotthibundhu, P. Phansuwan-pujito, and P. Govitrapong, Melatonin increases proliferation of cultured neural stem cells obtained from adult mouse subventricular zone, Journal of pineal research, vol.49, pp.291-300, 2010.

M. J. Kim, H. K. Kim, B. S. Kim, and S. V. Yim, Melatonin increases cell proliferation in the dentate gyrus of maternally separated rats, Journal of pineal research, vol.37, pp.193-197, 2004.

G. Ramirez-rodriguez, F. Klempin, H. Babu, G. Benitez-king, and G. Kempermann, Melatonin modulates cell survival of new neurons in the hippocampus of adult mice, Neuropsychopharmacology, vol.34, pp.2180-2191, 2009.

G. Ramirez-rodriguez, L. Ortiz-lopez, A. Dominguez-alonso, G. A. Benitez-king, and G. Kempermann, Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal neurogenesis of mice, Journal of pineal research, vol.50, pp.29-37, 2011.

R. Crupi, Melatonin's stimulatory effect on adult hippocampal neurogenesis in mice persists after ovariectomy, Journal of pineal research, vol.51, pp.353-360, 2011.

M. Banasr, A. Soumier, M. Hery, E. Mocaer, and A. Daszuta, Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis, Biol Psychiatry, vol.59, pp.1087-1096, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00087540

L. P. Niles, Neural stem cells express melatonin receptors and neurotrophic factors: colocalization of the MT1 receptor with neuronal and glial markers, BMC Neurosci, vol.5, 2004.

M. Pérez-martín, IGF-I stimulates neurogenesis in the hypothalamus of adult rats, Eur J Neurosci, vol.31, pp.1533-1548, 2010.

M. V. Kokoeva, H. Yin, and J. S. Flier, Evidence for constitutive neural cell proliferation in the adult murine hypothalamus, J Comp Neurol, vol.505, pp.209-220, 2007.

N. Haan, Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus, The Journal of neuroscience: the official journal of the Society for Neuroscience, vol.33, pp.6170-6180, 2013.

Y. Xu, Neurogenesis in the ependymal layer of the adult rat 3rd ventricle, Experimental neurology, vol.192, pp.251-264, 2005.

D. A. Lee, Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche, Nature neuroscience, vol.15, pp.700-702, 2012.

S. C. Robins, ?-Tanycytes of the adult hypothalamic third ventricle include distinct populations of FGF-responsive neural progenitors, Nat Commun, vol.4, 2013.

L. Dimou, C. Simon, F. Kirchhoff, H. Takebayashi, and M. Gotz, Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex, J Neurosci, vol.28, pp.10434-10442, 2008.

S. C. Robins, Extensive regenerative plasticity among adult NG2-glia populations is exclusively based on self-renewal, Glia, vol.61, pp.1735-1747, 2013.

S. C. Robins, Evidence for NG2-glia derived, adult-born functional neurons in the hypothalamus, PLoS One, vol.8, 2013.

T. Djogo, Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control, Cell metabolism, vol.23, pp.797-810, 2016.

D. A. Lee, Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice, Front Neurosci, vol.8, p.157, 2014.

M. Brus, Dynamics of olfactory and hippocampal neurogenesis in adult sheep, The Journal of comparative neurology, vol.521, pp.169-188, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01129681

P. Klosen, M. E. Sebert, K. Rasri, M. P. Laran-chich, and V. Simonneaux, TSH restores a summer phenotype in photoinhibited mammals via the RF-amides RFRP3 and kisspeptin, FASEB journal: official publication of the Federation of American Societies for Experimental Biology, vol.27, pp.2677-2686, 2013.

T. Ubuka, Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone, Endocrinology, vol.153, pp.373-385, 2012.

I. J. Clarke, Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion, Endocrinology, vol.149, pp.5811-5821, 2008.

J. T. Smith, Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropinreleasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep, Endocrinology, vol.149, pp.5770-5782, 2008.

A. Caraty, RF9 powerfully stimulates gonadotrophin secretion in the ewe: evidence for a seasonal threshold of sensitivity, J Neuroendocrinol, vol.24, pp.725-736, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01129618

F. Nottebohm, The road we travelled: discovery, choreography, and significance of brain replaceable neurons, Ann N Y Acad Sci, vol.1016, pp.628-658, 2004.

J. C. Thiery, Concentrations of estradiol in ewe cerebrospinal fluid are modulated by photoperiod through pineal-dependent mechanisms, Journal of pineal research, vol.41, pp.306-312, 2006.

J. Cognié and M. Migaud, Step by step experimental pinealectomy techniques in animals for researchers, vol.7, pp.137-151, 2013.

B. Malpaux, A. Daveau, F. Maurice, A. Locatelli, and J. C. Thiery, Evidence that melatonin binding sites in the pars tuberalis do not mediate the photoperiodic actions of melatonin on LH and prolactin secretion in ewes, Journal of reproduction and fertility, vol.101, pp.625-632, 1994.

D. C. Skinner, B. Malpaux, B. Delaleu, and A. Caraty, Luteinizing hormone (LH)-releasing hormone in third ventricular cerebrospinal fluid of the ewe: correlation with LH pulses and the LH surge, Endocrinology, vol.136, pp.3230-3237, 1995.

M. Batailler, A. Caraty, B. Malpaux, and Y. Tillet, Neuroanatomical organization of gonadotropin-releasing hormone neurons during the oestrus cycle in the ewe, BMC neuroscience, vol.5, 2004.

L. Tosca, Metformin decreases GnRH-and activin-induced gonadotropin secretion in rat pituitary cells: potential involvement of adenosine 5? monophosphate-activated protein kinase (PRKA), Biology of reproduction, vol.84, pp.351-362, 2011.

H. Guo, An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays, Proteome science, vol.10, 2012.