E. A. Hanon, G. A. Lincoln, J. M. Fustin, H. Dardente, M. Masson-pevet et al., Ancestral TSH mechanism signals summer in a photoperiodic mammal, Curr Biol, vol.18, pp.1147-1152, 2008.

H. Dardente, C. A. Wyse, M. J. Birnie, S. M. Dupre, A. S. Loudon et al., A molecular switch for photoperiod responsiveness in mammals, Curr Biol, vol.20, pp.2193-2198, 2010.

H. Dardente, D. G. Hazlerigg, and F. J. Ebling, Thyroid hormone and seasonal rhythmicity, Front Endocrinol (Lausanne), vol.5, p.19, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01129817

K. Ikegami, X. H. Liao, Y. Hoshino, H. Ono, W. Ota et al., Tissue-specific posttranslational modification allows functional targeting of thyrotropin, Cell Rep, vol.9, pp.801-810, 2014.

T. Yoshimura, S. Yasuo, M. Watanabe, M. Iigo, T. Yamamura et al., Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds, Nature, vol.426, pp.178-181, 2003.

P. Barrett, F. J. Ebling, S. Schuhler, D. Wilson, A. W. Ross et al., Hypothalamic thyroid hormone catabolism acts as a gatekeeper for the seasonal control of body weight and reproduction. Endocrinology, vol.148, pp.3608-3617, 2007.

N. Nakao, H. Ono, T. Yamamura, T. Anraku, T. Takagi et al., Thyrotrophin in the pars tuberalis triggers photoperiodic response, Nature, vol.452, pp.317-322, 2008.

H. Dardente and . Biology, The Double Life of the Seasonal Thyrotroph, Curr Biol, vol.25, pp.988-91, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02630440

S. H. Wood, H. C. Christian, K. Miedzinska, B. R. Saer, M. Johnson et al., Binary Switching of Calendar Cells in the Pituitary Defines the Phase of the Circannual Cycle in Mammals, Curr Biol, vol.25, pp.2651-2662, 2015.

D. Lomet, J. Cognie, D. Chesneau, E. Dubois, D. Hazlerigg et al., The impact of thyroid hormone in seasonal breeding has a restricted transcriptional signature, Cell Mol Life Sci, vol.75, p.28975373, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02071096

J. Castle-miller, D. O. Bates, and D. J. Tortonese, Mechanisms regulating angiogenesis underlie seasonal control of pituitary function, Proc Natl Acad Sci, vol.114, pp.2514-2523, 2017.

N. Ferrara, H. P. Gerber, and J. Lecouter, The biology of VEGF and its receptors, Nat Med, vol.9, pp.669-676, 2003.

N. Ferrara, Vascular endothelial growth factor: basic science and clinical progress, Endocr Rev, vol.25, pp.581-611, 2004.

D. O. Bates, T. G. Cui, J. M. Doughty, M. Winkler, M. Sugiono et al., VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma, Cancer Res, vol.62, pp.4123-4131, 2002.

S. Harris, M. Craze, J. Newton, M. Fisher, D. T. Shima et al., Do anti-angiogenic VEGF (VEGFxxxb) isoforms exist? A cautionary tale, PLoS One, vol.7, 2012.

, No VEGFAxxxb transcripts in the hypothalamus of the sheep PLOS ONE, 2018.

S. Bridgett, M. Dellett, and D. A. Simpson, RNA-Sequencing data supports the existence of novel VEGFA splicing events but not of VEGFAxxxb isoforms, Sci Rep, vol.7, pp.58-75, 2017.

F. J. Karsch, E. L. Bittman, D. L. Foster, R. L. Goodman, S. J. Legan et al., Neuroendocrine basis of seasonal reproduction, Recent Prog Horm Res, vol.40, pp.185-232, 1984.

A. Dobin, C. A. Davis, F. Schlesinger, J. Drenkow, C. Zaleski et al., STAR: ultrafast universal RNA-seq aligner, Bioinformatics, vol.29, pp.15-21, 2013.

D. O. Bates, A. Mavrou, Y. Qiu, J. G. Carter, M. Hamdollah-zadeh et al., Detection of VEGF-A(xxx) b isoforms in human tissues, PLoS One, vol.8, p.68399, 2013.

Y. Qiu, C. Hoareau-aveilla, S. Oltean, S. J. Harper, and D. O. Bates, The anti-angiogenic isoforms of VEGF in health and disease, Biochem Soc Trans, vol.37, pp.1207-1213, 2009.

D. G. Nowak, J. Woolard, E. M. Amin, O. Konopatskaya, M. A. Saleem et al., Expression of proand anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors, J Cell Sci, vol.121, pp.3487-3495, 2008.

J. A. Wells, A. R. Glassman, A. R. Ayala, L. M. Jampol, and L. P. Aiello, Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema, N Engl J Med, vol.372, pp.1193-1203, 2015.

R. M. Perrin, O. Konopatskaya, Y. Qiu, S. Harper, D. O. Bates et al., Diabetic retinopathy is associated with a switch in splicing from anti-to pro-angiogenic isoforms of vascular endothelial growth factor, Diabetologia, vol.48, pp.2422-2427, 2005.

A. H. Varey, E. S. Rennel, Y. Qiu, H. S. Bevan, R. M. Perrin et al., VEGF 165 b, an antiangiogenic VEGF-A isoform, binds and inhibits bevacizumab treatment in experimental colorectal carcinoma: balance of pro-and antiangiogenic VEGF-A isoforms has implications for therapy, Br J Cancer, vol.98, pp.1366-1379, 2008.

H. S. Bevan, N. M. Van-den-akker, Y. Qiu, J. A. Polman, R. R. Foster et al., The alternatively spliced anti-angiogenic family of VEGF isoforms VEGFxxxb in human kidney development, Nephron Physiol, vol.110, pp.57-67, 2008.

H. N. Jabbour, S. C. Boddy, and G. A. Lincoln, Pattern and localisation of expression of vascular endothelial growth factor and its receptor flt-1 in the ovine pituitary gland: expression is independent of hypothalamic control, Mol Cell Endocrinol, vol.134, pp.91-100, 1997.

S. M. Eswarappa, A. A. Potdar, W. J. Koch, Y. Fan, K. Vasu et al., Programmed translational readthrough generates antiangiogenic VEGF-Ax, Cell, vol.157, pp.1605-1618, 2014.

H. Xin, C. Zhong, E. Nudleman, and N. Ferrara, Evidence for Pro-angiogenic Functions of VEGF-Ax, Cell, vol.167, pp.275-284, 2016.

R. Catena, L. Larzabal, M. Larrayoz, E. Molina, J. Hermida et al., )(1)b and VEGF(1) (6)(5)b are weakly angiogenic isoforms of VEGF-A, Mol Cancer, vol.9, issue.1, pp.320-4598, 2010.

M. Guyot, C. Hilmi, D. Ambrosetti, M. Merlano, L. Nigro et al., Targeting the pro-angiogenic forms of VEGF or inhibiting their expression as anti-cancer strategies, Oncotarget, vol.8, pp.9174-9188, 2017.

S. F. Altschul, W. Gish, W. Miller, E. W. Myers, and D. J. Lipman, Basic local alignment search tool, J Mol Biol, vol.215, pp.403-410, 1990.

M. Zhao, X. Shi, J. Liang, Y. Miao, W. Xie et al., Expression of pro-and anti-angiogenic isoforms of VEGF in the mouse model of oxygen-induced retinopathy, Exp Eye Res, vol.93, pp.921-926, 2011.

C. Ergorul, A. Ray, W. Huang, D. Darland, Z. K. Luo et al., Levels of vascular endothelial growth factor-A165b (VEGF-A165b) are elevated in experimental glaucoma, Mol Vis, vol.14, pp.1517-1524, 2008.

R. A. Artac, R. M. Mcfee, R. A. Smith, M. M. Baltes-breitwisch, D. T. Clopton et al., Neutralization of vascular endothelial growth factor antiangiogenic isoforms is more effective than treatment with proangiogenic isoforms in stimulating vascular development and follicle progression in the perinatal rat ovary, Biol Reprod, vol.81, pp.978-988, 2009.

M. Guyot and G. Pagès, VEGF splicing and the role of VEGF splice variants: from physiological-pathological conditions to specific pre-mRNA splicing. VEGF signaling: Methods and Protocols, Methods in Molecular Biology, vol.1332, pp.3-23, 2015.