Prion protein expression and functional importance in developmental angiogenesis: role in oxidative stress and copper homeostasis, Antioxid. Redox Signal, vol.18, pp.400-411, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00734867
Absence of the prion protein homologue Doppel causes male sterility, EMBO J, vol.21, pp.3652-3658, 2002. ,
Nearly ubiquitous tissue distribution of the scrapie agent precursor protein, Neurology, vol.42, pp.149-156, 1992. ,
FOXL2 is a female sex-determining gene in the goat, Curr. Biol, vol.24, pp.404-408, 2014. ,
URL : https://hal.archives-ouvertes.fr/hal-02638689
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein, Nature, vol.356, pp.577-582, 1992. ,
Genomic organization, comparative analysis, and genetic polymorphisms of the bovine and ovine prion Doppel genes (PRND), Mamm. Genome, vol.12, pp.729-733, 2001. ,
Biological properties of the PRP-like Shadoo protein, Front. Biosci, vol.16, pp.1505-1516, 2011. ,
Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combinaison with PrP c -deficiency, Proc. Natl. Acad. Sci. U.S.A, vol.109, pp.9035-9040, 2012. ,
Gonad morphogenesis in vertebrates: divergent means to a convergent end, Annu. Rev. Cell Dev. Biol, vol.25, pp.457-482, 2009. ,
Compartmentalization of prion isoforms within the reproductive tract of the ram, Bio. Reprod, vol.71, pp.993-1001, 2004. ,
Dynamic expression of the prion-like protein Doppel in ovine testicular tissue, Int. J. Androl, vol.29, pp.400-408, 2006. ,
Sequence determination and expression of the ovine doppel-encoding gene in transgenic mice, Gene, vol.285, pp.287-290, 2002. ,
Association of the prion protein and its expression with ovarian follicle development in cattle, Mol. Reprod. Dev, vol.75, pp.243-249, 2008. ,
Prion protein is secreted in soluble forms in the epididymal fluid and proteolytically processed and transported in seminal plasma, Biol. Reprod, vol.67, pp.393-400, 2002. ,
Cell biological studies of the prion protein, Curr. Issues Mol. Biol, vol.1, pp.65-75, 1999. ,
Genomic assessment of the evolution of the prion protein gene family in vertebrates, Genomics, vol.95, pp.268-277, 2010. ,
Sry: the master switch in mammalian sex determination, Development, vol.137, pp.3921-3930, 2010. ,
Goat PRND expression pattern suggests its involvement in early sex differentiation, Dev. Dyn, vol.236, pp.836-842, 2007. ,
Complete genomic sequence and analysis of the prion protein gene region from three mammalian species, Genome Res, vol.8, pp.1022-1037, 1998. ,
Physiological expression of the gene for PrP-like protein, PrPLP/Dpl, by brain endothelial cells and its ectopic expression in neurons of PrP-deficient mice ataxic due to Purkinje cell degeneration, Am. J. Pathol, vol.157, issue.10, pp.64782-64789, 2000. ,
Genomic characterization of the human protein (PrP) gene locus, Mamm. Genome, vol.13, pp.696-703, 2002. ,
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal, Mol. Neurobiol, vol.8, pp.121-127, 1994. ,
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel, J. Mol. Biol, vol.292, pp.797-817, 1999. ,
Cellular prion protein status in sheep: tissue-specific biochemical signatures, J. Gen. Virol, vol.82, pp.2017-2024, 2001. ,
Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knoukout mice, Am. J. Pathol, vol.164, pp.2279-2288, 2004. ,
Prion protein and Shadoo are involved in overlapping embryonic pathways and trophoblastic development, PLoS ONE, vol.7, p.41959, 2012. ,
URL : https://hal.archives-ouvertes.fr/hal-00999993
The human "prion-like" protein Doppel is expressed in both Sertoli cells ans spermatozoa, J. Biol. Chem, vol.277, pp.43071-43078, 2002. ,
The prion-like protein Doppel enhances ovine spermatozoa fertilizing ability, Reprod. Domest. Anim, vol.47, pp.196-202, 2012. ,
Is prnt a pseudogene? Identification of ram Prt in testis and ejaculated spermatozoa, PLoS ONE, vol.7, p.42957, 2012. ,
Comparative genomic analysis of prion genes, BMC Genomics, vol.8, p.1, 2007. ,
Evolution of vertebrate genes related to prion and shadoo proteinsclues from comparative genomic analysis, Mol. Bio. Evol, vol.21, pp.2210-2231, 2004. ,
Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein, Gene, vol.314, pp.89-102, 2003. ,
, Prions. Proc. Natl. Acad. Sci. U.S.A, vol.95, pp.13363-13383, 1998.
The acrosomic reaction in stallion spermatozoa: inductive effect of the mare preovulatory follicular fluid, Biocell, vol.25, pp.115-120, 2001. ,
Identification of bovine doppel protein in testis, ovary and ejaculated spermatozoa, Theriogenology, vol.63, pp.1195-1206, 2005. ,
Threeexon structure of the gene encoding the rat prion protein and its expression in tissues, Virus Genes, vol.12, pp.15-20, 1996. ,
Evolutionary descent of prion genes from the ZIP family of metal ion transporters, PLoS ONE, vol.4, p.7208, 2009. ,
Spatio-developmental distribution of the prion-like protein doppel in Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids, Biol. Reprod, vol.74, pp.816-823, 2006. ,
A C-terminaltruncated PrP isoform is present in mature sperm, J. Biol. Chem, vol.274, pp.32153-32158, 1999. ,
Comparative study of cytoplasmic elimination in spermatids of selected mammalian species, Am. J. Anat, vol.178, pp.72-80, 1987. ,
Analysis of PRPc mRNA by in situ hybridization in brain, placenta, uterus and testis of rats, Intervirology, vol.38, pp.309-315, 1995. ,
The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression, Mamm. Genome, vol.12, pp.376-379, 2001. ,
Prp-c and Prp-sc at the fetal maternal interface, J. Biol. Chem, vol.276, pp.18229-18234, 2001. ,
The prion protein family: diversity, rivalry, and dysfunction, Biochim. Biophys. Acta, vol.1772, pp.654-672, 2007. ,
A study of intercellular bridges during spermatogenesis in the rat, Am. J. Anat, vol.180, pp.1-24, 1987. ,
Inherited prion diseases, Prion Biology and Diseases, pp.673-775, 2004. ,
Comparative sequence analysis and expression of bovine PrP gene in mouse L-929 cells, Virus Genes, vol.6, pp.343-356, 1992. ,
Generation of Sprn-regulated reporter mice reveals gonadic spatial expression of the prion-like protein Shadoo in mice, Biochem. Biophys. Res. Commun, vol.412, pp.752-756, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-01000156
Expression of proliferin-related protein in testis and the biological significance in testosterone production, Mol. Cell. Endocrinol, vol.343, pp.25-31, 2011. ,
, Conflict of Interest Statement: The authors declare that the research was con