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Communication Dans Un Congrès Année : 2020

In vitro dynamic gastrointestinal digestion of model infant formulas

Résumé

Considering the frequent need of developing new formulations that contain functional appeal to meet the scientific and technological demands, this study describes the influence of different model infant formulas composition on their behaviour under the simulated conditions of the infant gastrointestinal tract. To achieve this objective, rehydrated model infant formulas, produced with different types of proteins (whey protein isolate (WPI) or WPI+Lactoferrin (LF)) and oils (high oleic sunflower oil (HOSO), or a mixture of HOSO with medium chain triacyclglycerols (MCT)), were submitted to an in vitro dynamic gastrointestinal digestion system. During the digestion process the lipolysis, proteolysis and structural disintegration of the samples were evaluated. To perform that, analyses such as free fatty acids by gas chromatography, SDS-PAGE, confocal laser scanning microscopy and droplet size distribution were conducted. Changes in the microstructural properties at different digestion steps depended on the emulsifier (protein) properties and were attributed to pH changes and protein hydrolysis. For samples containing LF, lesser proteolysis was observed in the gastric phase and also less lipolysis in the intestinal phase. Thus, the protein remaining in the oil droplets surface may have hindered lipase access and consequently leading to a lower release of free fatty acids. However, for samples containing MCT, there was a considerable increase in the free fatty acids released. LF and MCT showed to be promising ingredients for the development of functional infant formulas. Furthermore, these results may be useful for controlled release applications and for modulating satiety responses to food ingestion
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Dates et versions

hal-02632130 , version 1 (27-05-2020)

Identifiants

  • HAL Id : hal-02632130 , version 1

Citer

Guilherme de Figueiredo Furtado, Olivia Ménard, Jordane Ossemond, Xiaoxi Yu, Amélie Deglaire, et al.. In vitro dynamic gastrointestinal digestion of model infant formulas. 15th International Hydrocolloids Conference, Mar 2020, Melbourne, Australia. ⟨hal-02632130⟩
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