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Journal Articles Science Year : 2014

The coffee genome provides insight into the convergent evolution of caffeine biosynthesis

1 LBGB - Laboratoire de Bioinformatique pour la Génomique et la Biodiversité
2 SUNY Buffalo - University at Buffalo [SUNY]
3 UMR IPME - UMR - Interactions Plantes Microorganismes Environnement
4 UMR AGAP - Amélioration génétique et adaptation des plantes méditerranéennes et tropicales
5 UMR DIADE - Diversité, adaptation, développement des plantes
6 ENEA - Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile = Italian National Agency for New Technologies, Energy and Sustainable Economic Development
7 Department of Mathematics and Statistics [Ottawa]
8 IG - Institut de Génomique d'Evry
9 IRD - Institut de Recherche pour le Développement
10 UMR RPB - Résistance des plantes aux bio-agresseurs
11 Bioversity, Parc Scientifique Agropolis II
12 Nestlé France
13 CeBiTec - Center for Biotechnology
14 Universität Bielefeld = Bielefeld University
15 URGI - Unité de Recherche Génomique Info
16 CEA - Commissariat à l'énergie atomique et aux énergies alternatives
17 Chongqing University of Science & Technology
18 UIUC - University of Illinois at Urbana-Champaign [Urbana]
19 IRBio UB - Institut de Recerca de la Biodiversitat - Biodiversity Research Institute [Barcelona, Spain]
20 University of Ottawa [Ottawa]
21 Department of Mathematics [College Park]
22 Università degli studi di Trieste = University of Trieste
23 Indonesian Coffee and Cocoa Research Institute
24 Embrapa Recursos Genéticos e Biotecnologia [Brasília]
25 QAAFI - Queensland Alliance for Agriculture and Food Innovation
26 UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations] - The University of Queensland
27 Hawaii Agriculture Research Center
28 University of Arizona
29 UMR 8030 - Génomique métabolique
30 UEVE - Université d'Évry-Val-d'Essonne
Adriana A. Alberti
Maud Lepelley
  • Function : Author
Michel Rigoreau
  • Function : Author

Abstract

Coffee is a valuable beverage crop due to its characteristic flavor, aroma, and the stimulating effects of caffeine. We generated a high-quality draft genome of the species Coffea canephora, which displays a conserved chromosomal gene order among asterid angiosperms. Although it shows no sign of the whole-genome triplication identified in Solanaceae species such as tomato, the genome includes several species-specific gene family expansions, among them N-methyltransferases (NMTs) involved in caffeine production, defense-related genes, and alkaloid and flavonoid enzymes involved in secondary compound synthesis. Comparative analyses of caffeine NMTs demonstrate that these genes expanded through sequential tandem duplications independently of genes from cacao and tea, suggesting that caffeine in eudicots is of polyphyletic origin.
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hal-02641562 , version 1 (07-12-2023)

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France Denoeud, Lorenzo Carretero-Paulet, Alexis Dereeper, Gaëtan Droc, Romain Guyot, et al.. The coffee genome provides insight into the convergent evolution of caffeine biosynthesis. Science, 2014, 345 (6201), pp.1181-1184. ⟨10.1126/science.1255274⟩. ⟨hal-02641562⟩
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