Role of insulin-like growth factors in embryonic and postnatal growth, Cell, vol.75, pp.73-82, 1993. ,
Natural and synthetic forms of insulin-like growth factor-1 (IGF-1) and the potent derivative, destripeptide IGF-1: biological activities and receptor binding, Biochem. Biophys. Res. Commun, vol.149, pp.398-404, 1987. ,
Specific binding of insulin-like growth factors 1 and 2 to the type 1 and type 2 receptors respectively, Biochem. J, vol.249, pp.721-726, 1988. ,
Plasma clearance and tissue distribution of labelled insulinlike growth factor-I (IGF-I), IGF-II and des(1-3)IGF-I in rats, J. Endocrinol, vol.128, pp.197-204, 1991. ,
Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I) and an analogue LR3IGF-I in pregnant rats, J. Endocrinol, vol.138, pp.327-336, 1993. ,
Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities, Am. J. Physiol. Endocrinol. Metab, vol.278, pp.967-976, 2000. ,
Structure of the Mr 140,000 growth hormonedependent insulin-like growth factor binding protein complex: determination by reconstitution and affinity-labeling, Proc. Natl. Acad. Sci. USA, vol.86, pp.6898-6902, 1989. ,
The C region of human insulin-like growth factor (IGF) I is required for high affinity binding to the type 1 IGF receptor, J. Biol. Chem, vol.264, pp.11004-11008, 1989. ,
Effect of rhGH and rhIGF-I treatment on protein utilization in elderly women, Am. J. Physiol, vol.272, pp.94-99, 1997. ,
A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum, Am. J. Physiol. Endocrinol. Metab, vol.284, pp.1149-1155, 2003. ,
Solution structure of human insulin-like growth factor 1, a nuclear magnetic resonance and restrained molecular dynamics study, Biochemistry, vol.30, pp.5484-5491, 1991. ,
The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways, J. Biol. Chem, vol.272, pp.6653-6662, 1997. ,
, Disease Models & Mechanisms
Sex-specific regulation of body size and bone slenderness by the acid labile subunit, J. Bone Miner. Res, vol.25, pp.2059-2068, 2010. ,
URL : https://hal.archives-ouvertes.fr/hal-02666501
Diet and insulinlike growth factor I in relation to body composition in women with exercise-induced hypothalamic amenorrhea, J. Am. Coll. Nutr, vol.9, pp.200-204, 1990. ,
Deficiency of the circulating insulin-like growth factor system associated with inactivation of the acid-labile subunit gene, N. Engl. J. Med, vol.350, pp.570-577, 2004. ,
Human acid-labile subunit deficiency: clinical, endocrine and metabolic consequences, Horm. Res, vol.72, pp.129-141, 2009. ,
Several insulin-like growth factor-I analogues and complexes of insulin-like growth factors-I and -II with insulinlike growth factor-binding protein-3 fail to mimic the effect of growth hormone upon lactation in the rat, J. Endocrinol, vol.140, pp.211-216, 1994. ,
The IGF axis and placental function. a mini review, Horm. Res, vol.69, pp.129-137, 2008. ,
Plasma clearance of chicken and human insulin-like growth factor-I and their association with circulating binding proteins in chickens, J. Endocrinol, vol.124, pp.361-370, 1990. ,
Aging somatotropic axis: mechanisms and implications of insulinlike growth factor-related binding protein adaptation, Endocrinol. Metab. Clin. North Am, vol.34, pp.865-876, 2005. ,
Enhanced potency of truncated insulin-like growth factor-I (des(1-3)IGF-I) relative to IGF-I in lit/lit mice, J. Endocrinol, vol.127, pp.401-405, 1990. ,
Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression, Endocrinology, vol.137, pp.321-330, 1996. ,
Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility, Mamm. Genome, vol.18, pp.492-507, 2007. ,
Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence, Novartis Found. Symp, vol.262, pp.247-260, 2004. ,
Production and characterization of recombinant insulin-like growth factor-I (IGF-I) and potent analogues of IGF-I, with Gly or Arg substituted for Glu3, following their expression in Escherichia coli as fusion proteins, J. Mol. Endocrinol, vol.8, pp.29-41, 1992. ,
GH/IGF-I regulation in obesity-mechanisms and practical consequences in children and adults, Horm. Res. Paediatr, vol.73, pp.153-160, 2010. ,
IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection, Am. J. Physiol, vol.260, pp.213-219, 1991. ,
Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: manipulation using the Cre/loxP system in transgenic mice, Mol. Endocrinol, vol.12, pp.1452-1462, 1998. ,
A highly efficient recombineeringbased method for generating conditional knockout mutations, Genome Res, vol.13, pp.476-484, 2003. ,
Growth enhancement of transgenic mice expressing human insulin-like growth factor I, Endocrinology, vol.123, pp.2827-2833, 1988. ,
Multivalent cations and ligand affinity of the type 1 insulin-like growth factor receptor on P2A2-LISN muscle cells, J. Cell Physiol, vol.176, pp.392-401, 1998. ,
IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms, J. Endocrinol, vol.175, pp.19-31, 2002. ,
Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5, Mol. Endocrinol, vol.20, pp.2173-2186, 2006. ,
Recombinant human insulin-like growth factor-I treatment inhibits gluconeogenesis in a transgenic mouse model of type 2 diabetes mellitus, Endocrinology, vol.147, pp.2619-2630, 2006. ,
Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1, Biochem. J, vol.258, pp.267-272, 1989. ,
Three-dimensional structure of human insulinlike growth factor-I (IGF-I) determined by 1H-NMR and distance geometry, Int. J. Pept. Protein Res, vol.41, pp.433-440, 1993. ,
The hormonal action of IGF1 in postnatal mouse growth, Proc. Natl. Acad. Sci. USA 105, pp.19378-19383, 2008. ,
Biodistribution of 125I-labeled des(1-3) insulin-like growth factor I in tumor-bearing nude mice and its in vitro catabolism, Cancer Res, vol.57, pp.2754-2759, 1997. ,
The bovine insulin-like growth factor (IGF) binding protein purified from conditioned medium requires the N-terminal tripeptide in IGF-1 for binding, Biochem. Biophys. Res. Commun, vol.151, pp.207-214, 1988. ,
The effects of recombinant human insulin-like growth factor-I and growth hormone on body composition in elderly women, J. Clin. Endocrinol. Metab, vol.80, pp.1845-1852, 1995. ,
Time spent walking or exercising and blood levels of insulinlike growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3): a large-scale crosssectional study in the Japan Collaborative Cohort study. Asian Pac, J. Cancer Prev, p.10, 2009. ,
Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene, N. Engl. J. Med, vol.335, pp.1363-1367, 1996. ,
Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity, Diabetes, vol.50, pp.1110-1118, 2001. ,
Circulating levels of IGF-1 directly regulate bone growth and density, J. Clin. Invest, vol.110, pp.771-781, 2002. ,
The role of circulating IGF-I: lessons from human and animal models, Endocrine, vol.19, pp.239-248, 2002. ,
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice, J. Clin. Invest, vol.113, pp.96-105, 2004. ,
The growth hormone-insulin like growth factor axis revisited: lessons from IGF-1 and IGF-1 receptor gene targeting, Pediatr. Nephrol, vol.20, pp.251-254, 2005. ,
The role of the growth hormone/insulinlike growth factor axis in tumor growth and progression: Lessons from animal models, Cytokine Growth Factor Rev, vol.16, pp.407-420, 2005. ,
The ternary IGF complex influences postnatal bone acquisition and the skeletal response to intermittent parathyroid hormone, J. Endocrinol, vol.189, pp.289-299, 2006. ,
Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions, J. Bone Miner. Res, vol.24, pp.1481-1492, 2009. ,
Serum complexes of insulin-like growth factor-1 modulate skeletal integrity and carbohydrate metabolism, FASEB J, vol.23, pp.709-719, 2009. ,