M. Alonso, J. Blanco, M. Blanco, and E. A. Gonzales, Frequent production of toxins by Escherichia coli isolated from urinary tract infections: relation with haemagglutination, FEMS Microbiol. Lett, vol.48, pp.391-396, 1987.

T. J. Baldwin, M. B. Lee-delaunay, S. Knutton, and P. H. Williams, Calcium-caldmodulin dependence of actin accretion and lethality in cultured Hep-2 cells infected with enteropathogenic Escherichia coli, Infect. Immun, vol.61, pp.760-763, 1993.

S. Bhakdi, N. Mackman, J. M. Nicaud, and I. B. Holland, Escherichia coli hemolysin may damage target cell membranes by generating transmembrane pores, Infect. Immun, vol.52, pp.63-69, 1986.

J. Blanco, E. A. Gonzáles, S. Garcia, M. Blanco, B. Regueiro et al., Production of toxins by Escherichia coli strains isolated from calves with diarrhea in Galicia (northwestern Spain), Vet. Microbiol, vol.18, pp.297-311, 1988.

A. Caprioli, G. Donelli, V. Falbo, R. Possenti, L. G. Roda et al., A cell-division-active protein from Escherichia coli, Biochem. Biophys. Res. Commun, vol.118, pp.587-593, 1984.

A. Caprioli, V. Falbo, L. G. Roda, F. M. Ruggeri, and C. Zona, Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations, Infect. Immun, vol.39, pp.1300-1306, 1983.

A. Caprioli, V. Falbo, F. M. Ruggeri, L. Baldassari, R. Bisicchia et al., Cytotoxic necrotizing factor production by hemolytic strains of Escherichia coli causing extraintestinal infections, J. Clin. Microbiol, vol.25, pp.146-149, 1987.

B. Colonna, L. Ranucci, P. A. Fradiani, M. Casalino, A. Calconi et al., Organization of aerobactin, hemolysin, and antibacterial resistance genes in lactose-negative Escherichia coli strains of serotype O4 isolated from children with diarrhea, Infect. Immun, vol.60, pp.5224-5231, 1992.

J. De-rycke, E. A. Gonzales, J. Blanco, E. Oswald, M. Blanco et al., Evidence of two types of cytotoxic necrotizing factor (CNF1 and CNF2) in human and animal clinical isolates of Escherichia coli, J. Clin. Microbiol, vol.28, pp.694-699, 1990.

J. De-rycke, J. F. Guillot, and R. Boivin, Cytotoxins in nonenteropathogenic strains of Escherichia coli isolated from feces of diarrheic calves, Vet. Microbiol, vol.15, pp.137-150, 1987.

J. De-rycke, L. Phan-than, and S. Bernard, Immunochemical identification and biological characterization of cytotoxic necrotizing factor of Escherichia coli, J. Clin. Microbiol, vol.27, pp.983-988, 1989.
URL : https://hal.archives-ouvertes.fr/hal-02720419

J. De-rycke and G. Plassiart, Toxic effects for lambs of cytotoxic necrotising factor (CNF) from Escherichia coli, Res. Vet. Sci, vol.49, pp.349-354, 1990.

G. Donelli and C. Fiorentini, Bacterial toxins acting on the cell cytoskeleton, Microbiologica, vol.17, pp.345-362, 1994.

E. A. Elsinghorst, Measurement of invasion by gentamicin resistance, Methods Enzymol, vol.236, pp.405-420, 1994.

V. Falbo, T. Pace, L. Picci, E. Pizzi, and A. Caprioli, Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli, Infect. Immun, vol.61, pp.4909-4914, 1993.

L. Falzano, C. Fiorentini, G. Donelli, E. Michel, C. Kocks et al., Induction of phagocytic behaviour in human epithelial cells by Escherichia coli cytotoxic necrotizing factor type 1, Mol. Microbiol, vol.9, pp.1247-1254, 1993.

B. B. Finlay, F. Heffron, and S. Falkow, Epithelial cell surfaces induce Salmonella proteins required for bacterial adhesion and invasion, Science, vol.243, pp.940-943, 1989.

C. Fiorentini, G. Arancia, A. Caprioli, V. Falbo, F. M. Ruggeri et al., Cytoskeletal changes induced in Hep-2 cells by the cytotoxic necrotizing factor of Escherichia coli, Toxicon, vol.26, pp.1047-1056, 1988.

W. Gorczyca, J. Gong, B. Ardelt, F. Traganos, and Z. Darzynkiewicz, The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor drugs, Cancer Res, vol.53, pp.3186-3192, 1993.

N. Khelef, A. Zychlinsky, and N. Guiso, Bordetella pertussis induces apoptosis in macrophages: role of adenylate cyclase hemolysin. Infect. Immun, vol.61, pp.4064-4071, 1993.

S. Knutton, T. Baldwin, P. H. Williams, and A. S. Mcneish, Actin accumulation at sites of bacterial adhesion to tissue cultures: basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coli, Infect. Immun, vol.57, pp.1290-1298, 1989.

A. Labigne, V. Cussac, and P. Courcoux, Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity, J. Bacteriol, vol.173, pp.1920-1931, 1991.

R. Marre, B. Kreft, and J. Hacker, Genetically engineered S and F1C fimbriae differ in their contribution to adherence of Escherichia coli to cultured renal tubular cells, Infect. Immun, vol.58, pp.3434-3437, 1990.

R. J. Muschel, H. B. Zhang, G. Iliakis, and W. G. Mckenna, Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation, Cancer Res, vol.51, pp.5113-5117, 1991.

E. Oswald, Unpublished data, 1995.

E. Oswald and J. De-rycke, A single protein of 110kDa is associated with the multinucleating and necrotizing activity coded by the Vir plasmid of Escherichia coli, FEMS Microbiol. Lett, vol.68, pp.279-284, 1990.
URL : https://hal.archives-ouvertes.fr/hal-02710043

E. Oswald, J. De-rycke, J. F. Guillot, and R. Boivin, Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains, FEMS Microbiol. Lett, vol.58, pp.983-988, 1989.
URL : https://hal.archives-ouvertes.fr/hal-02728376

E. Oswald, M. Sugai, A. Labigne, H. C. Wu, C. Fiorentini et al., Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins rho involved in assembly of actin stress fibers, Proc. Natl. Acad. Sci. USA, vol.91, pp.3814-3818, 1994.
URL : https://hal.archives-ouvertes.fr/hal-02706075

R. Rosqvist, K. E. Magnusson, and H. Wolf-watz, Target cell contact triggers expression and polarized transfer of Yersinia yopE cytotoxin into mammalian cells, EMBO J, vol.13, pp.964-972, 1994.

F. M. Ruggeri, C. Fiorentini, A. Caprioli, G. Arancia, V. Falbo et al., Hep-2 cells multinucleation induced by an Escherichia coli cytotoxic factor, IRCS Med. Sci, vol.14, pp.833-834, 1986.

J. Sambrook, E. F. Fritsch, and T. Maniatis, Molecular cloning: a laboratory manual, 1989.

H. W. Smith, Observations on Escherichia coli infections in calves, Proceedings of the First Seminar on ''Pathology'' in the CEC Programme of Coordination of Research in Beef Production. Commission of the European Communities, pp.47-59, 1975.

C. J. Smyth, M. Marron, and S. G. Smith, Fimbriae of Escherichia coli, Escherichia coli in domestic animals and humans. CAB International, pp.399-435, 1994.

M. Tabouret and J. De-rycke, Detection of cytotoxic necrotising factor (CNF) in extracts of Escherichia coli strains by enzyme-linked immunosorbent assay, J. Med. Microbiol, vol.32, pp.73-81, 1990.
URL : https://hal.archives-ouvertes.fr/hal-02707293

R. K. Taylor, C. Manoil, and J. J. Mekalanos, Broad-host-range vectors for delivery of TnphoA: use in genetic analysis of secreted virulence determinants of Vibrio cholerae, J. Bacteriol, vol.171, pp.1870-1878, 1989.

Y. P. Tsao, P. D'arpa, and L. F. Liu, The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34 cdc2 / cyclin B, Cancer Res, vol.52, pp.1823-1829, 1992.

I. Van-die, B. Van-geffen, W. Hoekstra, and H. Bergmans, Type F1C fimbriae of an uropathogenic Escherichia coli strain: cloning and characterization of the genes involved in the expression of the 1C antigen and nucleotide sequence of the subunit gene, Gene, vol.34, pp.187-196, 1985.

R. A. Welch and S. Falkow, Characterization of Escherichia coli hemolysins conferring quantitative differences in virulence, Infect. Immun, vol.43, pp.156-160, 1984.

A. P. Wilson, Animal cell culture, a practical approach, pp.263-303, 1992.

C. Wray, D. W. Piercy, P. J. Carroll, and W. A. Cooley, Experimental infection of neonatal pigs with CNF toxin-producing strains of Escherichia coli, Res. Vet. Sci, vol.54, pp.290-298, 1993.

A. Zychlinsky, M. C. Prevost, and P. J. Sansonetti, Shigella flexneri induces apoptosis in infected macrophages, Nature, vol.358, pp.167-168, 1992.