Copper-Catalyzed Domino Route to Natural Nostoclides and Analogues: A Total Synthesis of Nostoclides I and II
Résumé
An original and convenient domino route to natural nostoclides I and II has been developed using a two-step sequence consisting of a copper-catalyzed tandem reaction associated with Suzuki cross-coupling. The methodology employed for this total synthesis appeared to be an interesting and sufficiently flexible tool to allow the synthesis of numerous analogues of these nostoclides.