S. L. Abend, S. L. Fang, S. Alex, L. E. Braverman, and J. L. Leonard, Rapid alteration in circulating free thyroxine modulates pituitary type II 5 deiodinase and basal thyrotropin secretion in the rat, J. Clin. Invest, vol.88, pp.898-903, 1991.

, Évaluation des risques pour la santé humaine liés à une exposition au fipronil, AFSSA, 2005.

S. K. Balani, T. Zhu, T. J. Yang, Z. Liu, B. He et al., Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in rats, dogs, and monkeys, Drug Metab. Dispos, vol.30, pp.1059-1062, 2002.

B. Burchell and P. Weatherill, 4-Nitrophenol UDPglucuronyltransferase (rat liver), Methods Enzymol, vol.77, pp.169-177, 1981.

J. A. Carcillo, L. Doughty, D. Kofos, R. F. Frye, S. S. Kaplan et al., Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure, Intensive Care Med, vol.29, pp.980-984, 2003.

S. L. Chan and J. H. Yeung, Modulation of antipyrine clearance by polysaccharide peptide (PSP) isolated from Coriolus versicolor in the rat, Food Chem. Toxicol, vol.44, pp.1607-1612, 2006.

P. C. Das, Y. Cao, N. Cherrington, E. Hodgson, and R. L. Rose, Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes, Chem. Biol. Interact, vol.164, pp.200-214, 2006.

I. Distefano, J. J. Feng, and D. , Comparative aspects of the distribution, metabolism, and excretion of six iodothyronines in the rat, Endocrinology, vol.123, pp.2514-2525, 1988.

. Fao/who, Pesticide Residues in Food-Fipronil, 1997.

G. C. Hard, Recent developments in the investigation of thyroid regulation and thyroid carcinogenesis, Environ. Health Perspect, vol.106, pp.427-436, 1998.

A. Hood, R. Hashmi, and C. D. Klaassen, Effects of microsomal enzyme inducers on thyroid-follicular cell proliferation, hyperplasia, and hypertrophy, Toxicol. Appl. Pharmacol, vol.160, pp.163-170, 1999.

P. M. Hurley, Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents, Environ. Health Perspect, vol.106, pp.437-445, 1998.

S. Ikushiro, Y. Emi, and T. Iyanagi, Activation of glucuronidation through reduction of a disulfide bond in rat UDP-glucuronosyltransferase 1A6, Biochemistry, vol.41, pp.12813-12820, 2002.

X. C. Kretschmer and W. S. Baldwin, CAR and PXR: xenosensors of endocrine disrupters?, Chem. Biol. Interact, vol.155, pp.111-128, 2005.

G. Lemaire, W. Mnif, J. M. Pascussi, A. Pillon, F. Rabenoelina et al., Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system, Toxicol. Sci, vol.91, pp.501-509, 2006.

C. Liddle, B. J. Goodwin, J. George, M. Tapner, and G. C. Farrell, Separate and interactive regulation of cytochrome P450 3A4 by triiodothyronine, dexamethasone, and growth hormone in cultured hepatocytes, J. Clin. Endocrinol. Metab, vol.83, pp.2411-2416, 1998.

O. H. Lowry, N. J. Rosebrough, A. L. Farr, and R. J. Randall, Protein measurement with the Folin phenol reagent, J. Biol. Chem, vol.193, pp.265-275, 1951.

D. E. Matthew and J. B. Houston, Drug metabolizing capacity in vitro and in vivo. II. Correlations between hepatic microsomal monooxygenase markers in phenobarbital-induced rats, Biochem. Pharmacol, vol.40, pp.751-758, 1990.

F. Mohamed, L. Senarathna, A. Percy, M. Abeyewardene, G. Eaglesham et al., Acute human self-poisoning with the N-phenylpyrazole insecticide fipronil-a GABAA-gated chloride channel blocker, J. Toxicol. Clin. Toxicol, vol.42, pp.955-963, 2004.

T. Oinonen and K. O. Lindros, Zonation of hepatic cytochrome P-450 expression and regulation, Biochem. J, vol.329, pp.17-35, 1998.

L. Savu, R. Vranckx, M. Rouaze-romet, M. Maya, E. A. Nunez et al., A senescence up-regulated protein: the rat thyroxine-binding globulin (TBG), Biochim. Biophys. Acta, vol.1097, pp.19-22, 1991.

G. C. Schussler, The thyroxine-binding proteins, Thyroid, vol.10, pp.141-149, 2000.

J. V. St-peter and W. M. Awni, Quantifying hepatic function in the presence of liver disease with phenazone (antipyrine) and its metabolites, Clin. Pharmacokinet, vol.20, pp.50-65, 1991.

T. Szakacs, Z. Veres, and L. Vereczkey, Effect of phenobarbital and spironolactone treatment on the oxidative metabolism of antipyrine by rat liver microsomes, Pol. J. Pharmacol, vol.53, pp.11-19, 2001.

E. Tanaka, S. Kobayashi, A. Aramphongphan, N. Kurata, K. Oguchi et al., The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator, J. Pharmacobiodyn, vol.8, pp.773-779, 1985.

J. Tang, K. Amin-usmani, E. Hodgson, and R. L. Rose, In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam, Chem. Biol. Interact, vol.147, pp.319-329, 2004.

C. C. Tingle, J. A. Rother, C. F. Dewhurst, S. Lauer, and W. J. King, Fipronil: environmental fate, ecotoxicology, and human health concerns, Rev. Environ. Contam. Toxicol, vol.176, pp.1-66, 2003.

T. J. Visser, E. Kaptein, J. A. Van-raaij, C. T. Joe, T. Ebner et al., Multiple UDP-glucuronyltransferases for the glucuronidation of thyroid hormone with preference for 3,3 , 5 -triiodothyronine (reverse T3), FEBS Lett, vol.315, pp.65-68, 1993.

T. J. Visser, E. Kaptein, H. Van-toor, J. A. Van-raaij, . Van-den et al., Glucuronidation of thyroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions, Endocrinology, vol.133, pp.2177-2186, 1993.

R. Vranckx, M. Rouaze-romet, L. Savu, P. Mechighel, M. Maya et al., Regulation of rat thyroxine-binding globulin and transthyretin: studies in thyroidectomized and hypophysectomized rats given tri-iodothyronine or/and growth hormone, J. Endocrinol, vol.142, pp.77-84, 1994.

E. D. Williams, Mechanisms and pathogenesis of thyroid cancer in animals and man, Mutat. Res, vol.333, pp.123-129, 1995.

H. Wong, L. D. Lehman-mckeeman, M. F. Grubb, S. J. Grossman, V. M. Bhaskaran et al., Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in rats, Toxicol. Sci, vol.84, pp.232-242, 2005.

H. Yamada, I. Distefano, J. J. Yen, Y. M. Nguyen, and T. T. , Steady-state regulation of whole-body thyroid hormone pool sizes and interconversion rates in hypothyroid and moderately T3-stimulated rats, Endocrinology, vol.137, pp.5624-5633, 1996.

D. Zalko, C. Prouillac, A. Riu, E. Perdu, L. Dolo et al., Biotransformation of the flame retardant tetrabromobisphenol A by human and rat sub-cellular liver fractions, Chemosphere, vol.64, pp.318-327, 2006.