Quasispecies structure and persistence of RNA viruses - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Emerging Infectious Diseases Year : 1998

Quasispecies structure and persistence of RNA viruses

Abstract

Viral quasispecies are closely related (but nonidentical) mutant and recombinant viral genomes subjected to continuous genetic variation, competition, and selection. Quasispecies structure and dynamics of replicating RNA enable virus populations to persist in their hosts and cause disease. We review mechanisms of viral persistence in cells, organisms, and populations of organisms and suggest that the critical interplay between host and viral influences (including in some cases the quasispecies organization) is the main driving force for long-term survival of viruses in nature.
No file

Dates and versions

hal-02695774 , version 1 (01-06-2020)

Identifiers

  • HAL Id : hal-02695774 , version 1
  • PRODINRA : 178514
  • PUBMED : 9866728
  • WOS : 000077532500002

Cite

Esteban Domingo, Eric Baranowski, Carmen M. Ruiz-Jarabo, Ana M. Martín-Hernández, Juan C. Sáiz, et al.. Quasispecies structure and persistence of RNA viruses. Emerging Infectious Diseases, 1998, 4 (4), pp.521-527. ⟨hal-02695774⟩

Collections

INRAE
7 View
0 Download

Altmetric

Share

Gmail Facebook X LinkedIn More