A. P. Simopoulos, A. Leaf, and N. Salem, Workshop statement on the essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids, Prostaglandins Leukot Essent Fatty Acids, vol.63, pp.119-121, 2000.

F. Calon and G. Cole, Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies, Prostaglandins Leukot Essent Fatty Acids, vol.77, pp.287-293, 2007.

R. P. Bazinet and S. Layé, Polyunsaturated fatty acids and their metabolites in brain function and disease, Nat Rev Neurosci, vol.15, pp.771-785, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02640592

A. Berger, G. Crozier, T. Bisogno, P. Cavaliere, S. Innis et al., Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets, Proc Natl Acad Sci USA, vol.98, pp.6402-6406, 2001.

S. Watanabe, M. Doshi, and T. Hamazaki, Polyunsaturated fatty acid (PUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice, Prostaglandins Leukot Essent Fatty Acids, vol.69, pp.51-59, 2003.

A. Artmann, G. Petersen, L. I. Hellgren, J. Boberg, C. Skonberg et al.,

H. Nguyen, R. C. Bagot, J. Diorio, T. P. Wong, and M. J. Meaney, Maternal care differentially affects neuronal excitability and synaptic plasticity in the dorsal and ventral hippocampus, Neuropsychopharmacology, vol.40, pp.1590-1599, 2015.

S. M. Innis, Dietary omega 3 fatty acids and the developing brain, Brain Res, vol.1237, pp.35-43, 2008.

S. I. Rapoport, J. S. Rao, and M. Igarashi, Brain metabolism of nutritionally essential polyunsaturated fatty acids depends on both the diet and the liver, Prostaglandins Leukot Essent Fatty Acids, vol.77, pp.251-261, 2007.

C. Joffre, A. Nadjar, M. Lebbadi, F. Calon, and S. Laye, n-3 LCPUFA improves cognition: the young, the old and the sick, Prostaglandins Leukot Essent Fatty Acids, vol.91, pp.1-20, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02639255

J. S. Rao, R. N. Ertley, J. C. Demar, S. I. Rapoport, R. P. Bazinet et al., Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex, Mol Psychiatry, vol.12, pp.151-157, 2007.

J. T. Green, Z. Liu, and R. P. Bazinet, Brain phospholipid arachidonic acid half-lives are not altered following 15 weeks of N-3 polyunsaturated fatty acid adequate or deprived diet, J Lipid Res, vol.51, pp.535-543, 2010.

A. Moranis, J. Delpech, D. Smedt-peyrusse, V. , A. A. Guesnet et al., Long term adequate n-3 polyunsaturated fatty acid diet protects from depressive-like behavior but not from working memory disruption and brain cytokine expression in aged mice, Brain Behav Immun, vol.26, pp.721-731, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02647840

M. Igarashi, H. Kim, C. L. Ma, K. Rapoport, and S. I. , Dietary n-6 polyunsaturated fatty acid deprivation increases docosahexaenoic acid metabolism in rat brain, J Neurochem, vol.120, pp.985-997, 2012.

C. Madore, A. Nadjar, J. Delpech, A. Sere, A. A. Portal et al., Nutritional n-3 PUFAs deficiency during perinatal periods alters brain innate immune system and neuronal plasticity-associated genes, Brain Behav Immun, vol.41, pp.22-31, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02640850

D. Piomelli, G. Astarita, and R. Rapaka, A neuroscientist's guide to lipidomics, Nat Rev Neurosci, vol.8, pp.743-754, 2007.

M. Pinot, S. Vanni, S. Pagnotta, S. Lacas-gervais, L. Payet et al., Polyunsaturated phospholipids facilitate membrane deformation and fission by endocytic proteins, Science, vol.345, pp.693-697, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01141794

C. Chen and N. G. Bazan, Lipid signaling: sleep, synaptic plasticity, and neuroprotection, Prostaglandins Other Lipid Mediat, vol.77, pp.65-76, 2005.

C. N. Serhan, Pro-resolving lipid mediators are leads for resolution physiology, Nature, vol.510, pp.92-101, 2014.

E. A. Dennis and P. C. Norris, Eicosanoid storm in infection and inflammation, Nat Rev Immunol, vol.15, pp.511-523, 2015.

N. Salem, B. Litman, H. Y. Kim, and K. Gawrisch, Mechanisms of action of docosahexaenoic acid in the nervous system, Lipids, vol.36, pp.945-959, 2001.

P. E. Castillo, T. J. Younts, A. E. Chávez, and Y. Hashimotodani, Endocannabinoid signaling and synaptic function, Neuron, vol.76, pp.70-81, 2012.

H. Y. Kim, M. Akbar, A. Lau, and L. Edsall, Inhibition of neuronal apoptosis by docosahexaenoic acid, J Biol Chem, vol.22, pp.35215-35223, 2000.

F. Calderon and H. Kim, Docosahexaenoic acid promotes neurite growth in hippocampal neurons, J Neurochem, vol.90, pp.979-988, 2004.

H. Kim, A. A. Spector, and Z. Xiong, A synaptogenic amide N-docosahexaenoylethanolamide promotes hippocampal development, Prostaglandins Other Lipid Mediat, vol.96, 2011.

W. J. Lukiw, J. Cui, V. L. Marcheselli, M. Bodker, A. Botkjaer et al., A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease, J Clin Invest, vol.115, pp.2774-2783, 2005.

N. G. Bazan, The docosanoid neuroprotectin D1 induces homeostatic regulation of neuroinflammation and cell survival, Prostaglandins Leukot Essent Fatty Acids, vol.88, pp.127-129, 2013.

A. Wu, Z. Ying, and F. Gomez-pinilla, Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats, J Neurotrauma, vol.21, pp.1457-1467, 2004.

F. Calon, Omega-3 polyunsaturated fatty acids in Alzheimer's disease: key questions and partial answers, Curr Alzheimer Res, vol.8, pp.470-478, 2011.

S. C. Cunnane, M. Plourde, F. Pifferi, M. Bégin, C. Féart et al., docosahexaenoic acid and Alzheimer's disease, Prog Lipid Res, vol.48, pp.239-256, 2009.

F. Kamel, S. M. Goldman, D. M. Umbach, H. Chen, G. Richardson et al., Dietary fat intake, pesticide use, and Parkinson's disease, Parkinsonism Relat Disord, vol.20, pp.82-87, 2014.

M. H. Rapaport, A. A. Nierenberg, P. J. Schettler, B. Kinkead, A. Cardoos et al., Inflammation as a predictive biomarker for response to omega-3 fatty acids in major depressive disorder: a proof-of-concept study, Mol Psychiatry, vol.21, pp.71-79, 2016.

,

J. Delpech, A. Thomazeau, C. Madore, C. Bosch-bouju, T. Larrieu et al., Dietary n-3 PUFAs deficiency increases vulnerability to inflammation-induced spatial memory impairment, Neuropsychopharmacology, vol.40, pp.2774-2787, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02640350

V. F. Labrousse, A. Nadjar, C. Joffre, L. Costes, A. A. Grégoire et al., Short-term long chain omega3 diet protects from neuroinflammatory processes and memory impairment in aged mice, PLoS ONE, vol.7, p.36861, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01191175

J. Delpech, C. Madore, C. Joffre, A. A. Kang, J. X. Nadjar et al., Transgenic increase in n-3/n-6 fatty acid ratio protects against cognitive deficits induced by an immune challenge through decrease of neuroinflammation, Neuropsychopharmacology, vol.40, pp.525-536, 2015.
URL : https://hal.archives-ouvertes.fr/hal-02635645

B. D. Heifets and P. E. Castillo, Endocannabinoid signaling and long-term synaptic plasticity, Annu Rev Physiol, vol.71, pp.283-306, 2009.

N. Ueda, K. Tsuboi, and T. Uyama, Metabolism of endocannabinoids and related N-acylethanolamines: canonical and alternative pathways, FEBS J, vol.280, pp.1874-1894, 2013.

D. Piomelli, More surprises lying ahead. The endocannabinoids keep us guessing, Neuropharmacology, vol.76, pp.228-234, 2014.

D. Robbe, J. Bockaert, and O. J. Manzoni, Metabotropic glutamate receptor 2/3-dependent long-term depression in the nucleus accumbens is blocked in morphine withdrawn mice, Eur J Neurosci, vol.16, pp.2231-2235, 2002.

D. Robbe, G. Alonso, S. Chaumont, J. Bockaert, and O. J. Manzoni, Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses, J Neurosci, vol.22, pp.4346-4356, 2002.

E. Fino, V. Paille, Y. Cui, T. Morera-herreras, J. Deniau et al., Distinct coincidence detectors govern the corticostriatal spike timing-dependent plasticity, J Physiol (Lond), vol.588, pp.3045-3062, 2010.
URL : https://hal.archives-ouvertes.fr/hal-02407307

A. Tanimura, M. Yamazaki, Y. Hashimotodani, M. Uchigashima, S. Kawata et al., The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission, Neuron, vol.65, pp.320-327, 2010.

M. Reisenberg, P. K. Singh, G. Williams, and P. Doherty, The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling, Philos Trans R Soc Lond, B, Biol Sci, vol.367, pp.3264-3275, 2012.

S. Nicolussi and J. Gertsch, Endocannabinoid transport revisited, Vitam Horm, vol.98, pp.441-485, 2015.

K. Ahn, M. K. Mckinney, and B. F. Cravatt, Enzymatic pathways that regulate endocannabinoid signaling in the nervous system, Chem Rev, vol.108, pp.1687-1707, 2008.

A. Ludányi, S. Hu, M. Yamazaki, A. Tanimura, D. Piomelli et al., Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus, Neuroscience, vol.174, pp.50-63, 2011.

A. Viader, J. L. Blankman, P. Zhong, X. Liu, J. E. Schlosburg et al., Metabolic Interplay between astrocytes and neurons regulates endocannabinoid action, Cell Rep, vol.12, pp.798-808, 2015.

M. G. Cascio, PUFA-derived endocannabinoids: an overview, Proc Nutr Soc, vol.72, pp.451-459, 2013.

M. Alhouayek and G. G. Muccioli, COX-2-derived endocannabinoid metabolites as novel inflammatory mediators, Trends Pharmacol Sci, vol.35, pp.284-292, 2014.

D. J. Hermanson, J. C. Gamble-george, L. J. Marnett, and S. Patel, Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation, Trends Pharmacol Sci, vol.35, pp.358-367, 2014.

G. Astarita, F. Ahmed, and D. Piomelli, Identification of biosynthetic precursors for the endocannabinoid anandamide in the rat brain, J Lipid Res, vol.49, pp.48-57, 2008.

J. Fu, G. Bottegoni, O. Sasso, R. Bertorelli, W. Rocchia et al., A catalytically silent FAAH-1 variant drives anandamide transport in neurons, Nat Neurosci, vol.15, pp.64-69, 2012.

K. Leung, M. W. Elmes, S. T. Glaser, D. G. Deutsch, and M. Kaczocha, Role of FAAH-like anandamide transporter in anandamide inactivation, PLoS ONE, vol.8, p.79355, 2013.

D. Marzo, V. , D. Petrocellis, and L. , Why do cannabinoid receptors have more than one endogenous ligand, Philos Trans R Soc Lond B Biol Sci, vol.367, pp.3216-3228, 2012.

K. Starowicz, S. Nigam, D. Marzo, and V. , Biochemistry and pharmacology of endovanilloids, Pharmacol Ther, vol.114, pp.13-33, 2007.

A. Tóth, P. M. Blumberg, and J. Boczán, Anandamide and the vanilloid receptor (TRPV1)

, Vitam Horm, vol.81, pp.389-419, 2009.

B. A. Grueter, G. Brasnjo, and R. C. Malenka, Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens, Nat Neurosci, vol.13, pp.1519-1525, 2010.

A. E. Chávez, C. Q. Chiu, and P. E. Castillo, TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus, Nat Neurosci, vol.13, pp.1511-1518, 2010.

N. Puente, Y. Cui, O. Lassalle, M. Lafourcade, F. Georges et al., Polymodal activation of the endocannabinoid system in the extended amygdala, Nat Neurosci, vol.14, pp.1542-1547, 2011.
URL : https://hal.archives-ouvertes.fr/hal-01160051

E. A. Placzek, Y. Okamoto, N. Ueda, and E. L. Barker, Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown, Neuropharmacology, vol.55, pp.1095-1104, 2008.

S. Petrosino, D. Marzo, and V. Faah, therapeutic opportunities from regulating endocannabinoid levels, Curr Opin Investig Drugs, vol.11, pp.51-62, 2010.

C. J. Fowler, The potential of inhibitors of endocannabinoid metabolism for drug development: a critical review, Handb Exp Pharmacol, vol.231, pp.95-128, 2015.

A. Lodola, R. Castelli, M. Mor, and S. Rivara, Fatty acid amide hydrolase inhibitors: a patent review, Expert Opin Ther Pat, vol.25, pp.1247-1266, 2009.

Y. Gao, D. V. Vasilyev, M. B. Goncalves, F. V. Howell, C. Hobbs et al., Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice, J Neurosci, vol.30, pp.2017-2024, 2010.

D. Leung, A. Saghatelian, G. M. Simon, and B. F. Cravatt, Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids, Biochemistry, vol.45, pp.4720-4726, 2006.

K. Tsuboi, Y. Okamoto, N. Ikematsu, M. Inoue, Y. Shimizu et al., Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through Nacylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent andindependent pathways, Biochim Biophys Acta, vol.1811, pp.565-577, 2011.

J. T. Wood, J. S. Williams, L. Pandarinathan, D. R. Janero, C. J. Lammi-keefe et al., Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma, J Lipid Res, vol.51, pp.1416-1423, 2010.

T. Sheskin, L. Hanus, J. Slager, Z. Vogel, and R. Mechoulam, Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor, J Med Chem, vol.40, pp.659-667, 1997.

J. Meijerink, M. Balvers, R. Witkamp, and . N-, Acyl amines of docosahexaenoic acid and other n-3 polyunsatured fatty acids-from fishy endocannabinoids to potential leads, Br J Pharmacol, vol.169, pp.772-783, 2013.

H. Kim and A. A. Spector, Synaptamide, endocannabinoid-like derivative of docosahexaenoic acid with cannabinoid-independent function, Prostaglandins Leukot Essent Fatty Acids, vol.88, pp.121-125, 2013.

D. Cao, K. Kevala, J. Kim, H. Moon, S. B. Jun et al., Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function, J Neurochem, vol.111, pp.510-521, 2009.

T. Bisogno, I. Delton-vandenbroucke, A. Milone, M. Lagarde, D. Marzo et al., Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina, Arch Biochem Biophys, vol.370, pp.300-307, 1999.

C. E. Ramsden, D. Zamora, A. Makriyannis, J. T. Wood, J. D. Mann et al., Dietinduced changes in n-3-and n-6-derived endocannabinoids and reductions in headache pain and psychological distress, J Pain, vol.16, pp.707-716, 2015.

F. Piscitelli, G. Carta, T. Bisogno, E. Murru, L. Cordeddu et al., Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice, Nutr Metab (Lond), vol.8, p.51, 2011.

M. Balvers, K. Verhoeckx, S. Bijlsma, C. M. Rubingh, J. Meijerink et al., Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues, Metabolomics, vol.8, pp.1130-1147, 2012.

I. Matias, G. Carta, E. Murru, S. Petrosino, S. Banni et al., Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes, Biochim Biophys Acta, vol.1781, pp.52-60, 2008.

B. Batetta, M. Griinari, G. Carta, E. Murru, A. Ligresti et al., Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats, J Nutr, vol.139, pp.1495-1501, 2009.

A. R. Alvheim, M. K. Malde, D. Osei-hyiaman, Y. H. Lin, R. J. Pawlosky et al., Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity, Obesity (Silver Spring), vol.20, pp.1984-1994, 2012.

A. R. Alvheim, B. E. Torstensen, Y. H. Lin, H. H. Lillefosse, E. Lock et al., Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet, Lipids, vol.49, pp.59-69, 2014.

,

J. Kim, M. E. Carlson, G. A. Kuchel, J. W. Newman, and B. A. Watkins, Dietary DHA reduces downstream endocannabinoid and inflammatory gene expression and epididymal fat mass while improving aspects of glucose use in muscle in C57BL/6J mice, Int J Obes (Lond), vol.40, pp.129-137, 2016.

L. Yan, X. Bai, Z. Fang, C. L. Xu, S. Wu et al., Effect of different dietary omega-3/omega-6 fatty acid ratios on reproduction in male rats, Lipids Health Dis, vol.12, p.33, 2013.

S. Banni, D. Marzo, and V. , Effect of dietary fat on endocannabinoids and related mediators: consequences on energy homeostasis, inflammation and mood, Mol Nutr Food Res, vol.54, pp.82-92, 2010.

W. Mazier, N. Saucisse, B. Gatta-cherifi, and D. Cota, The endocannabinoid system: pivotal orchestrator of obesity and metabolic disease, Trends Endocrinol Metab, vol.26, pp.524-537, 2015.

J. M. Mcpartland, G. W. Guy, D. Marzo, and V. , Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system, PLoS ONE, vol.9, p.89566, 2014.

A. H. Koolman, V. W. Bloks, M. H. Oosterveer, J. I. Kuipers, F. Sauer et al., Metabolic responses to long-term pharmacological inhibition of CB1-receptor activity in mice in relation to dietary fat composition, Int J Obes (Lond), vol.34, pp.374-384, 2010.

V. Chiurchiù, L. Battistini, and M. Maccarrone, Endocannabinoid signaling in innate and adaptive immunity, Immunology, 2015.

R. Marion-letellier, G. Savoye, and S. Ghosh, Polyunsaturated fatty acids and inflammation, IUBMB Life, vol.67, pp.659-667, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01959545

M. Masoodi, O. Kuda, M. Rossmeisl, P. Flachs, and J. Kopecky, Lipid signaling in adipose tissue: connecting inflammation & metabolism, Biochim Biophys Acta, vol.1851, pp.503-518, 2015.

B. A. Watkins, H. Hutchins, Y. Li, and M. F. Seifert, The endocannabinoid signaling system: a marriage of PUFA and musculoskeletal health, J Nutr Biochem, vol.21, pp.1141-1152, 2010.

H. L. Hutchins, Y. Li, K. Hannon, and B. A. Watkins, Eicosapentaenoic acid decreases expression of anandamide synthesis enzyme and cannabinoid receptor 2 in osteoblast-like cells, J Nutr Biochem, vol.22, pp.195-200, 2011.

C. L. Wainwright and L. Michel, Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection, Proc Nutr Soc, vol.72, pp.460-469, 2013.

J. Endo and M. Arita, Cardioprotective mechanism of omega-3 polyunsaturated fatty acids, J Cardiol, vol.67, pp.22-27, 2016.

N. Battista, R. Meccariello, G. Cobellis, S. Fasano, D. Tommaso et al., The role of endocannabinoids in gonadal function and fertility along the evolutionary axis, Mol Cell Endocrinol, vol.355, pp.1-14, 2012.

R. Meccariello, N. Battista, H. B. Bradshaw, and H. Wang, Updates in reproduction coming from the endocannabinoid system, Int J Endocrinol, p.412354, 2014.

P. Bovolin, E. Cottone, V. Pomatto, S. Fasano, R. Pierantoni et al., Endocannabinoids are involved in male vertebrate reproduction: regulatory mechanisms at central and gonadal level, Front Endocrinol (Lausanne), vol.5, p.54, 2014.

T. L. Vrablik and J. L. Watts, Polyunsaturated fatty acid derived signaling in reproduction and development: insights from Caenorhabditis elegans and Drosophila melanogaster, Mol Reprod Dev, vol.80, pp.244-259, 2013.

I. Björkgren, H. Gylling, H. Turunen, I. Huhtaniemi, L. Strauss et al., Imbalanced lipid homeostasis in the conditional Dicer1 knockout mouse epididymis causes instability of the sperm membrane, FASEB J, vol.29, pp.433-442, 2015.

J. Pan, H. Zhang, W. Null, Y. Guo, N. Null et al., Some subtypes of endocannabinoid/endovanilloid receptors mediate docosahexaenoic acidinduced enhanced spatial memory in rats, Brain Res, vol.1412, pp.18-27, 2011.

D. Yamada, J. Takeo, P. Koppensteiner, K. Wada, and M. Sekiguchi, Modulation of fear memory by dietary polyunsaturated fatty acids via cannabinoid receptors, Neuropsychopharmacology, vol.39, pp.1852-1860, 2014.

L. Martini, M. Waldhoer, M. Pusch, V. Kharazia, J. Fong et al., Ligand-induced down-regulation of the cannabinoid 1 receptor is mediated by the G-protein-coupled receptor-associated sorting protein GASP1, FASEB J, vol.21, pp.802-811, 2007.

R. Stadel, K. H. Ahn, and D. A. Kendall, The cannabinoid type-1 receptor carboxyl-terminus, more than just a tail, J Neurochem, vol.117, pp.1-18, 2011.

M. F. Lazenka, D. E. Selley, and L. J. Sim-selley, Brain regional differences in CB1 receptor adaptation and regulation of transcription, Life Sci, vol.92, pp.446-452, 2013.

R. Cachope, Functional diversity on synaptic plasticity mediated by endocannabinoids, Philos Trans R Soc Lond, B, Biol Sci, vol.367, pp.3242-3253, 2012.

,

C. Glangetas, D. Girard, L. Groc, G. Marsicano, F. Chaouloff et al., Stress switches cannabinoid type-1 (CB1) receptor-dependent plasticity from LTD to LTP in the bed nucleus of the stria terminalis, J Neurosci, vol.33, pp.19657-19663, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01160039

Y. Cui, V. Paillé, H. Xu, S. Genet, B. Delord et al., Endocannabinoids mediate bidirectional striatal spike-timing-dependent plasticity, J Physiol (Lond), vol.593, pp.2833-2849, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01141205

R. Crupi, A. Marino, and S. Cuzzocrea, n-3 fatty acids: role in neurogenesis and neuroplasticity, Curr Med Chem, vol.20, pp.2953-2963, 2013.

A. R. Patten, H. M. Sickmann, R. A. Dyer, S. M. Innis, and B. R. Christie, Omega-3 fatty acids can reverse the long-term deficits in hippocampal synaptic plasticity caused by prenatal ethanol exposure, Neurosci Lett, vol.551, pp.7-11, 2013.

D. Arsenault, C. Julien, C. T. Chen, R. P. Bazinet, and F. Calon, Dietary intake of unsaturated fatty acids modulates physiological properties of entorhinal cortex neurons in mice, J Neurochem, vol.122, pp.427-443, 2012.

A. Latour, B. Grintal, G. Champeil-potokar, M. Hennebelle, M. Lavialle et al., Omega-3 fatty acids deficiency aggravates glutamatergic synapse and astroglial aging in the rat hippocampal CA1, Aging Cell, vol.12, pp.76-84, 2013.
URL : https://hal.archives-ouvertes.fr/hal-02325139

M. J. Mcfarland and E. L. Barker, Lipid rafts: a nexus for endocannabinoid signaling?, Life Sci, vol.77, pp.1640-1650, 2005.

J. Barnett-norris, D. Lynch, and P. H. Reggio, Lipids, lipid rafts and caveolae: their importance for GPCR signaling and their centrality to the endocannabinoid system, Life Sci, vol.77, pp.1625-1639, 2005.

M. Maccarrone, D. Chiara, V. Gasperi, V. Viscomi, M. T. Rossi et al., Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum, J Neurochem, vol.109, pp.371-381, 2009.

D. Lingwood and K. Simons, Lipid rafts as a membrane-organizing principle, Science, vol.327, pp.46-50, 2010.

H. Hering, C. Lin, and M. Sheng, Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability, J Neurosci, vol.23, pp.3262-3271, 2003.

S. R. Wassall and W. Stillwell, Polyunsaturated fatty acid-cholesterol interactions: domain formation in membranes, Biochim Biophys Acta, vol.1788, pp.24-32, 2009.

S. R. Wassall and W. Stillwell, Docosahexaenoic acid domains: the ultimate non-raft membrane domain, Chem Phys Lipids, vol.153, pp.57-63, 2008.

S. R. Shaikh, Biophysical and biochemical mechanisms by which dietary N-3 polyunsaturated fatty acids from fish oil disrupt membrane lipid rafts, J Nutr Biochem, vol.23, pp.101-105, 2012.

K. M. Appleton, P. J. Rogers, and A. R. Ness, Updated systematic review and meta-analysis of the effects of n-3 long-chain polyunsaturated fatty acids on depressed mood, Am J Clin Nutr, vol.91, pp.757-770, 2010.

P. Lin, S. Huang, and K. Su, A meta-analytic review of polyunsaturated fatty acid compositions in patients with depression, Biol Psychiatry, vol.68, pp.140-147, 2010.

R. K. Mcnamara, C. Hahn, R. Jandacek, T. Rider, P. Tso et al., Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder, Biol Psychiatry, vol.62, pp.17-24, 2007.

R. K. Mcnamara, R. Jandacek, P. Tso, Y. Dwivedi, X. Ren et al., Lower docosahexaenoic acid concentrations in the postmortem prefrontal cortex of adult depressed suicide victims compared with controls without cardiovascular disease, J Psychiatr Res, vol.47, pp.1187-1191, 2013.

J. J. Rakofsky and B. W. Dunlop, Review of nutritional supplements for the treatment of bipolar depression, Depress Anxiety, vol.31, pp.379-390, 2014.

L. Gertsik, R. E. Poland, C. Bresee, and M. H. Rapaport, Omega-3 fatty acid augmentation of citalopram treatment for patients with major depressive disorder, J Clin Psychopharmacol, vol.32, pp.61-64, 2012.

I. Carrié, M. Clément, D. De-javel, H. Francès, and J. M. Bourre, Phospholipid supplementation reverses behavioral and biochemical alterations induced by n-3 polyunsaturated fatty acid deficiency in mice, J Lipid Res, vol.41, pp.473-480, 2000.

T. Larrieu, M. L. Hilal, L. M. Hilal, C. Fourrier, D. Smedt-peyrusse et al., Nutritional omega-3 modulates neuronal morphology in the prefrontal cortex along with depression-related behaviour through corticosterone secretion, Transl Psychiatry, vol.4, p.437, 2014.
URL : https://hal.archives-ouvertes.fr/hal-02635379

B. Levant, N-3 (omega-3) polyunsaturated Fatty acids in the pathophysiology and treatment of depression: pre-clinical evidence, CNS Neurol Disord Drug Targets, vol.12, pp.450-459, 2013.

V. R. Venna, D. Deplanque, C. Allet, K. Belarbi, M. Hamdane et al., PUFA induce antidepressant-like effects in parallel to structural and molecular changes in the hippocampus, Psychoneuroendocrinology, vol.34, pp.199-211, 2009.

A. C. Ferraz, A. M. Delattre, R. G. Almendra, M. Sonagli, C. Borges et al., Chronic ?-3 fatty acids supplementation promotes beneficial effects on anxiety, cognitive and Dietary Omega-6/Omega-3 and Endocannabinoids: Implications for Brain Health and Diseases

, depressive-like behaviors in rats subjected to a restraint stress protocol, Behav Brain Res, vol.219, pp.116-122, 2011.

B. B. Gorzalka and M. N. Hill, Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants, Prog Neuropsychopharmacol Biol Psychiatry, vol.35, pp.1575-1585, 2011.

O. Valverde and M. Torrens, CB1 receptor-deficient mice as a model for depression, Neuroscience, vol.204, pp.193-206, 2012.

R. J. Bluett, J. C. Gamble-george, D. J. Hermanson, N. D. Hartley, L. J. Marnett et al., Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation, Transl Psychiatry, vol.4, p.408, 2014.

Z. Qin, X. Zhou, N. R. Pandey, H. A. Vecchiarelli, C. A. Stewart et al., Chronic stress induces anxiety via an amygdalar intracellular cascade that impairs endocannabinoid signaling, Neuron, vol.85, pp.1319-1331, 2015.

S. Patel, P. J. Kingsley, K. Mackie, L. J. Marnett, and D. G. Winder, Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala, Neuropsychopharmacology, vol.34, pp.2699-2709, 2009.

C. G. Reich, M. E. Taylor, and M. M. Mccarthy, Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats, Behav Brain Res, vol.203, pp.264-269, 2009.

W. Wang, D. Sun, B. Pan, C. J. Roberts, X. Sun et al., Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress, Neuropsychopharmacology, vol.35, pp.2249-2261, 2010.

J. J. Sumislawski, T. S. Ramikie, and S. Patel, Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation, Neuropsychopharmacology, vol.36, pp.2750-2761, 2011.

M. N. Hill, G. E. Miller, E. J. Carrier, B. B. Gorzalka, and C. J. Hillard, Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress, Psychoneuroendocrinology, vol.34, pp.1257-1262, 2009.

R. A. Mangieri and D. Piomelli, Enhancement of endocannabinoid signaling and the pharmacotherapy of depression, Pharmacol Res, vol.56, pp.360-366, 2007.

M. N. Hill and S. Patel, Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses, Biol Mood Anxiety Disord, vol.3, p.19, 2013.

T. Larrieu, M. L. Hilal, D. Smedt-peyrusse, V. Sans, N. Layé et al., Nutritional Omega-3 deficiency alters glucocorticoid receptor-signaling pathway and neuronal morphology in regionally distinct brain structures associated with emotional deficits, nutritional Omega-3 deficiency alters glucocorticoid receptor-signaling pathway and neuronal morphology in regionally distinct brain structures associated with emotional deficits, Neural Plast, vol.2016, p.8574830, 2015.

R. Malcher-lopes, A. Franco, and J. G. Tasker, Glucocorticoids shift arachidonic acid metabolism toward endocannabinoid synthesis: a non-genomic anti-inflammatory switch, Eur J Pharmacol, vol.583, pp.322-339, 2008.

S. Patel, C. T. Roelke, D. J. Rademacher, W. E. Cullinan, and C. J. Hillard, Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamicpituitary-adrenal axis, Endocrinology, vol.145, pp.5431-5438, 2004.

B. Kluger, P. Triolo, W. Jones, and J. Jankovic, The therapeutic potential of cannabinoids for movement disorders, Mov Disord, vol.30, pp.313-327, 2015.

G. Hacioglu, Y. Seval-celik, G. Tanriover, O. Ozsoy, E. Saka-topcuoglu et al., Docosahexaenoic acid provides protective mechanism in bilaterally MPTP-lesioned rat model of Parkinson's disease, Folia Histochem Cytobiol, vol.50, pp.228-238, 2012.

M. S. Shchepinov, V. P. Chou, E. Pollock, J. W. Langston, C. R. Cantor et al., Isotopic reinforcement of essential polyunsaturated fatty acids diminishes nigrostriatal degeneration in a mouse model of Parkinson's disease, Toxicol Lett, vol.207, pp.97-103, 2011.

G. Tanriover, Y. Seval-celik, O. Ozsoy, G. Akkoyunlu, F. Savcioglu et al., The effects of docosahexaenoic acid on glial derived neurotrophic factor and neurturin in bilateral rat model of Parkinson's disease, Folia Histochem Cytobiol, vol.48, pp.434-441, 2010.

M. Bousquet, K. Gue, V. Emond, P. Julien, J. X. Kang et al., Transgenic conversion of omega-6 into omega-3 fatty acids in a mouse model of Parkinson's disease, J Lipid Res, vol.52, pp.263-271, 2011.

M. Bousquet, F. Calon, and F. Cicchetti, Impact of ?-3 fatty acids in Parkinson's disease, Ageing Res Rev, vol.10, pp.453-463, 2011.

J. Dong, J. D. Beard, D. M. Umbach, Y. Park, X. Huang et al., Dietary fat intake and risk for Parkinson's disease, Mov Disord, vol.29, pp.1623-1630, 2014.

F. Calon, G. P. Lim, F. Yang, T. Morihara, B. Teter et al., Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model, Neuron, vol.43, pp.633-645, 2004.

F. Calon, G. P. Lim, T. Morihara, F. Yang, O. Ubeda et al., Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the Dietary Omega-6/Omega-3 and Endocannabinoids: Implications for Brain Health and Diseases

, Alzheimer's disease, Eur J Neurosci, vol.22, pp.617-626, 2005.

S. C. Cunnane, R. Chouinard-watkins, C. A. Castellano, and P. Barberger-gateau, Docosahexaenoic acid homeostasis, brain aging and Alzheimer's disease: can we reconcile the evidence?, Prostaglandins Leukot Essent Fatty Acids, vol.88, pp.61-70, 2013.

D. Piomelli and O. Sasso, Peripheral gating of pain signals by endogenous lipid mediators, Nat Neurosci, vol.17, pp.164-174, 2014.

D. Piomelli, A. G. Hohmann, V. Seybold, and B. D. Hammock, A lipid gate for the peripheral control of pain, J Neurosci, vol.34, pp.15184-15191, 2014.

J. S. Rao, H. Lee, S. I. Rapoport, and R. P. Bazinet, Mode of action of mood stabilizers: is the arachidonic acid cascade a common target? Mol Psychiatry, vol.13, pp.585-596, 2008.

F. Chauveau, T. Cho, M. Perez, M. Guichardant, A. Riou et al., Braintargeting form of docosahexaenoic acid for experimental stroke treatment: MRI evaluation and anti-oxidant impact, Curr Neurovasc Res, vol.8, pp.95-102, 2011.
URL : https://hal.archives-ouvertes.fr/hal-02653073

A. Y. Taha, T. Zahid, T. Epps, M. Trepanier, W. M. Burnham et al., Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo, Brain Res, vol.1537, pp.9-17, 2013.

M. Trépanier, A. Y. Taha, R. L. Mantha, F. A. Ciobanu, Q. H. Zeng et al., Increases in seizure latencies induced by subcutaneous docosahexaenoic acid are lost at higher doses, Epilepsy Res, vol.99, pp.225-232, 2012.

A. Gaffuri, D. Ladarre, and Z. Lenkei, Type-1 cannabinoid receptor signaling in neuronal development, Pharmacology, vol.90, pp.19-39, 2012.

A. B. Roland, A. Ricobaraza, D. Carrel, B. M. Jordan, F. Rico et al., Cannabinoidinduced actomyosin contractility shapes neuronal morphology and growth, Elife, vol.3, p.3159, 2014.
URL : https://hal.archives-ouvertes.fr/inserm-01356874