Molecular pathways regulating EGF-induced epitheliomesenchymal transition in human ovarian surface epithelium, Am. J. Physiol. Cell Physiol, vol.290, pp.1532-1542, 2006. ,
Mechanisms of palatal epithelial seam disintegration by transforming growth factor (TGF) beta3, Dev. Biol, vol.309, pp.193-207, 2007. ,
Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence, Cancer Cell, vol.14, pp.79-89, 2008. ,
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse, Development, vol.135, pp.501-511, 2008. ,
Erk5 controls slug expression and keratinocyte activation during wound healing, Mol. Biol. Cell, vol.19, pp.4738-4749, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00318681
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions, Clin. Exp. Metastasis, vol.25, pp.685-693, 2008. ,
The Snail genes as inducers of cell movement and survival: implications in development and cancer, Development, vol.132, pp.3151-3161, 2005. ,
The transcription factor snail is a repressor of Ecadherin gene expression in epithelial tumour cells, Nat. Cell Biol, vol.2, pp.84-89, 2000. ,
A natural antisense transcript regulates Zeb2/ Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition, Genes Dev, vol.22, pp.756-769, 2008. ,
Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition, Trends Cell Biol, vol.18, pp.357-359, 2008. ,
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression, Nat. Cell Biol, vol.2, pp.76-83, 2000. ,
Contact inhibition of locomotion in vivo controls neural crest directional migration, Nature, vol.456, pp.957-961, 2008. ,
The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition, Mol. Cell. Biol, vol.21, pp.8184-8188, 2001. ,
Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel, Cancer Res, vol.67, pp.1979-1987, 2007. ,
miR-200b mediates post-transcriptional repression of ZFHX1B, RNA, vol.13, pp.1172-1178, 2007. ,
Prototypical type I E-cadherin and type II cadherin-7 mediate very distinct adhesiveness through their extracellular domains, J. Biol. Chem, vol.281, pp.2901-2910, 2006. ,
Targeted therapies in control of EMT in carcinoma and fibrosis, Drug Discov. Today, vol.4, pp.261-267, 2008. ,
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak, Dev. Cell, vol.1, pp.37-49, 2001. ,
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents, Mol. Cancer Ther, vol.8, pp.1055-1066, 2009. ,
A critical role for Cadherin6B in regulating avian neural crest emigration, Dev. Biol, vol.312, pp.533-544, 2007. ,
Endothelial cell migration directs testis cord formation, Dev. Biol, vol.326, pp.112-120, 2009. ,
Intravital imaging of cell movement in tumours, Nat. Rev. Cancer, vol.3, pp.921-930, 2003. ,
Notch in the pathway: the roles of Notch signaling in neural crest development, Semin. Cell Dev. Biol, vol.16, pp.663-672, 2005. ,
Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis, Circ. Res, vol.10, pp.856-863, 2006. ,
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors, Cancer Res, vol.64, pp.5527-5534, 2004. ,
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma, Mol. Cancer Ther, vol.6, pp.1683-1691, 2007. ,
MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer, Cell, vol.113, pp.207-219, 2003. ,
Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis, Oncogene, vol.27, pp.1218-1230, 2008. ,
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression, Genes Dev, vol.15, pp.2140-2151, 2009. ,
, Developmental Biology, 2006.
A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes, Oncogene, vol.25, pp.3170-3185, 2006. ,
Insulinlike growth factor-I-dependent up-regulation of ZEB1 drives epithelial-tomesenchymal transition in human prostate cancer cells, Cancer Res, vol.68, pp.2479-2488, 2008. ,
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1, Nat. Cell Biol, vol.10, pp.593-601, 2008. ,
A common somitic origin for embryonic muscle progenitors and satellite cells, Nature, vol.435, pp.954-958, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00118545
A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila, Cell, vol.101, pp.523-531, 2000. ,
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail, EMBO J, vol.25, pp.3534-3545, 2006. ,
The small GTPase RhoV is an essential regulator of neural crest induction in Xenopus, Dev. Biol, vol.310, pp.113-128, 2007. ,
URL : https://hal.archives-ouvertes.fr/hal-02267391
KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis ein breast cancer, Nat. Cell Biol, vol.11, pp.1297-1304, 2009. ,
Identification of selective inhibitors of cancer stem cells by high-throughput screening, Cell, vol.138, pp.645-659, 2009. ,
Snail regulates cell-matrix adhesion by regulation of the expression of integrins and basement membrane paroteins, J. Biol. Chem, vol.283, pp.23514-23523, 2008. ,
Back and forth between cell fate specification and movement during vertebrate gastrulation, Curr. Opin. Genet. Dev, vol.18, pp.311-316, 2008. ,
TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer, J. Clin. Oncol, vol.23, pp.5892-5899, 2005. ,
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer, Cell Stem Cell, vol.1, pp.313-323, 2007. ,
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor, Mol. Cell. Biol, vol.28, pp.4772-4781, 2008. ,
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation, J. Clin. Invest, vol.117, pp.353-363, 2007. ,
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition, J. Cell Biol, vol.182, pp.1217-1230, 2008. ,
, , 2007.
, Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase, Oncogene, vol.26, pp.2781-2790
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis, Nat. Cell Biol, vol.10, pp.202-210, 2008. ,
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression, J. Clin. Invest, vol.114, pp.569-581, 2004. ,
Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin, Cancer Res, vol.67, pp.7972-7976, 2007. ,
Systemic spread is an early step in breast cancer, Cancer Cell, vol.13, pp.58-68, 2008. ,
Epilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cells, J. Cell Sci, vol.119, pp.3856-3865, 2006. ,
Evidence that fibroblasts derive from epithelium during tissue fibrosis, J. Clin. Invest, vol.110, pp.341-350, 2002. ,
Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin, Oncogene, vol.25, pp.7117-7130, 2006. ,
,
, The FERM protein Epb4.1l5 is required for organization of the neural plate and for the epithelial-mesenchymal transition at the primitive streak of the mouse embryo, Development, vol.134, pp.2007-2016
Epithelial-mesenchymal transition in cervical cancer: correlation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation, Clin. Cancer Res, vol.14, pp.4743-4750, 2008. ,
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin, J. Exp. Med, vol.204, pp.2935-2948, 2007. ,
A dynamic epicardial injury response supports progenitor cell activity during zebrafish heart regeneration, Cell, vol.127, pp.607-619, 2006. ,
Twist1-mediated adriamycin-induced epithelialmesenchymal transition relates to multidrug resistance and invasive potential in breast cancer cells, Clin. Cancer Res, vol.15, pp.2657-2665, 2009. ,
PRL3 promotes cell invasion and proliferation by down-regulation of Csk leading to Src activation, J. Biol. Chem, vol.282, pp.5413-5419, 2007. ,
Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs, Cell Stem Cell, vol.3, pp.55-68, 2008. ,
Zeb1 links epithelial-mesenchymal transition and cellular senescence, Development, vol.135, pp.579-588, 2008. ,
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression, Cancer Res, vol.67, pp.9066-9076, 2007. ,
Inflammation and EMT: an alliance towards organ fibrosis and cancer progression, EMBO Molecular Medicine, vol.1, pp.303-314, 2009. ,
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion, Cancer Cell, vol.4, pp.499-515, 2003. ,
Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes, Cancer Res, vol.68, pp.4525-4530, 2008. ,
Human skin fibroblasts: From mesodermal to hepatocyte-like differentiation, Hepatology, vol.46, pp.1574-1585, 2007. ,
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer, Nature, vol.449, pp.682-688, 2007. ,
Coupling Met to specific pathways results in distinct developmental outcomes, Mol. Cell, vol.7, pp.1293-1306, 2001. ,
The epithelial-mesenchymal transition generates cells with properties of stem cells, Cell, vol.133, pp.704-715, 2008. ,
Repression of prostaglandin dehydrogenase by epidermal growth factor and snail increases prostaglandin E2 and promotes cancer progression, Cancer Res, vol.66, pp.6649-6656, 2006. ,
Pulsed actin-myosin network contractions drive apical constriction, Nature, vol.457, pp.495-499, 2009. ,
Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition, J. Cell Sci, vol.119, pp.4541-4553, 2006. ,
Snail family members and cell survival in physiological and pathological cleft palates, Dev. Biol, vol.265, pp.207-218, 2004. ,
, TGF? in cancer. Cell, vol.134, pp.215-229, 2008.
Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition, J. Clin. Invest, vol.119, pp.2663-2677, 2009. ,
Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis, Nat. Cell Biol, vol.11, pp.257-268, 2009. ,
Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart, Cells Tissues Organs, vol.185, pp.146-156, 2007. ,
,
, The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling, J. Clin. Invest, vol.119, pp.2678-2690
The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer, Cancer Res, vol.67, pp.1105-1112, 2007. ,
Genomic analysis of gastrulation and organogenesis in the mouse, Dev. Cell, vol.13, pp.897-907, 2007. ,
Sclerotome development and morphogenesis: when experimental embryology meets genetics, Int. J. Dev. Biol, vol.49, pp.301-308, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-01183680
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis, Cancer Cell, vol.2, pp.451-461, 2002. ,
The transcriptional repressor Snail promotes mammary tumor recurrence, Cancer Cell, vol.8, pp.197-209, 2005. ,
Snail genes at the crossroads of symmetric and asymmetric processes in the developing mesoderm, EMBO Rep, vol.8, pp.104-109, 2007. ,
Generation of breast cancer stem cells through epithelial-mesenchymal transition, PLoS ONE, vol.3, 2008. ,
Transcriptional regulation of cell polarity in EMT and cancer, Oncogene, vol.27, pp.6958-6969, 2008. ,
Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling, J. Cell Biol, vol.179, pp.1027-1042, 2007. ,
Snail family genes are required for leftright asymmetry determination, but not neural crest formation, in mice, Proc. Natl. Acad. Sci. USA, vol.103, pp.10300-10304, 2006. ,
Neural crest cell-cell adhesion controlled by sequential and subpopulation-specific expression of novel cadherins, Development, vol.121, pp.1321-1332, 1995. ,
Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP), Anat. Rec, vol.258, pp.119-127, 2000. ,
, , 2004.
, Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1, Dev. Cell, vol.7, pp.425-438
RhoA and microtubule dynamics control cell-basement membrane interaction in EMT during gastrulation, Nat. Cell Biol, vol.10, pp.765-775, 2008. ,
Control of cell behavior during vertebrate development by Slug, a zinc finger gene, Science, vol.264, pp.835-839, 1994. ,
Slug is a direct Notch target required for initiation of cardiac cushion cellularization, J. Cell Biol, vol.182, pp.315-325, 2008. ,
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways, Hepatology, vol.48, pp.909-919, 2008. ,
Dynamic behavior of the cadherin-based cell-cell adhesion system during Drosophila gastrulation, Dev. Biol, vol.203, pp.435-450, 1998. ,
Global regulatory logic for specification of an embryonic cell lineage, Proc. Natl. Acad. Sci. USA 105, pp.5955-5962, 2008. ,
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines, Oncogene, vol.27, pp.4690-4701, 2008. ,
Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity, Science, vol.307, pp.1603-1609, 2005. ,
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2, Genes Dev, vol.22, pp.894-907, 2008. ,
Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo, J. Cell Sci, vol.117, pp.2827-2839, 2004. ,
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?, Nat. Rev. Cancer, vol.7, pp.415-428, 2007. ,
Snail1 transcriptional repressor binds to its own promoter and controls its expression, Nucleic Acids Res, vol.34, pp.2077-2084, 2006. ,
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas, Int. J. Cancer, vol.119, pp.2098-2104, 2006. ,
LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest, Development, vol.131, pp.4455-4465, 2004. ,
A causal role for E-cadherin in the transition from adenoma to carcinoma, Nature, vol.392, pp.190-193, 1998. ,
A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis, Dev. Cell, vol.15, pp.813-828, 2008. ,
Insulin and insulin-like growth factor signalling in neoplasia, Nat. Rev. Cancer, vol.8, pp.915-928, 2008. ,
Tumour budding in colorectal carcinoma, Histopathology, vol.50, pp.151-162, 2007. ,
A twist for survival and cancer progression, Br. J. Cancer, vol.94, pp.13-17, 2006. ,
Efficient tumour formation by single human melanoma cells, Nature, vol.456, pp.593-598, 2008. ,
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability, Nature, vol.436, pp.123-127, 2005. ,
Development of heart valves requires Gata4 expression in endothelial-derived cells, Development, vol.133, pp.3607-3618, 2006. ,
The multifaceted role of periostin in tumorigenesis, Cell. Mol. Life Sci, vol.66, pp.2219-2230, 2009. ,
Notch signaling mediates hypoxia-induced tumor cell migration and invasion, Proc. Natl. Acad. Sci. USA 105, pp.6392-6397, 2008. ,
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice, Lab. Invest, vol.84, pp.1259-1270, 2004. ,
Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development, Development, vol.133, pp.1323-1333, 2006. ,
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction, J. Clin. Invest, vol.112, pp.1486-1494, 2003. ,
A gene regulatory network orchestrates neural crest formation, Nat. Rev. Mol. Cell Biol, vol.9, pp.557-568, 2008. ,
Sonic Hedgehog-Gli1 signaling pathway might become an effective therapeutic target in gastrointestinal neuroendocrine carcinomas, Cancer Biol. Ther, vol.5, pp.1530-1538, 2006. ,
Antagonistic roles of fulllength N-cadherin and its soluble BMP cleavage product in neural crest delamination, Development, vol.134, pp.491-501, 2007. ,
Molecular correlates of gefitinib responsiveness in human bladder cancer cells, Mol. Cancer Ther, vol.6, pp.277-285, 2007. ,
Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells, Cancer Res, vol.66, pp.11370-11380, 2006. ,
A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors, Genes Dev, vol.21, pp.2131-2136, 2007. ,
The class I bHLH factors E2-2A and E2-2B regulate, EMT. J. Cell Sci, vol.122, pp.1014-1024, 2009. ,
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer, Cancer Res, vol.68, pp.537-544, 2008. ,
Small non-coding RNAs in animal development, Nat. Rev. Mol. Cell Biol, vol.9, pp.219-230, 2008. ,
Snail promotes Wnt target gene expression and interacts with beta-catenin, Oncogene, vol.27, pp.5075-5080, 2008. ,
Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-?B/Snail1 pathway, Dis. Model. Mech, vol.1, pp.264-274, 2008. ,
Interleukin-6 induces an epithelialmesenchymal transition phenotype in human breast cancer cells, Oncogene, vol.28, pp.2940-2947, 2009. ,
Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy, J. Am. Soc. Nephrol, vol.17, pp.3382-3393, 2006. ,
Snail2 directly represses cadherin6B during epithelial-to-mesenchymal transitions of the neural crest, Development, vol.134, pp.1481-1490, 2007. ,
Molecular mechanism of liver development and regeneration, Int. Rev. Cytol, vol.259, pp.1-48, 2007. ,
In vivo evidence for short-and longrange cell communication in cranial neural crest cells, Development, vol.131, pp.6141-6151, 2004. ,
Complex networks orchestrate epithelial-mesenchymal transitions, Nat. Rev. Mol. Cell Biol, vol.7, pp.131-142, 2006. ,
Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition, Cancer Res, vol.65, pp.9455-9462, 2005. ,
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition, J. Biol. Chem, vol.174, pp.175-183, 2008. ,
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation, Genes Dev, vol.18, pp.99-115, 2004. ,
Epithelial-mesenchymal transition process in human embryonic stem cells cultured in feeder-free conditions, Mol. Hum. Reprod, vol.13, pp.21-32, 2007. ,
LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells, Int. J. Oncol, vol.35, pp.813-821, 2009. ,
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes, Mol. Cancer Res, vol.1, pp.68-78, 2002. ,
Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells, Mech. Dev, vol.75, pp.171-174, 1998. ,
Snail blocks the cell cycle and confers resistance to cell death, Genes Dev, vol.18, pp.1131-1143, 2004. ,
SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelialmesenchymal transition, Nat. Cell Biol, vol.11, pp.943-950, 2009. ,
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions, Nat. Rev. Cancer, vol.8, pp.755-768, 2008. ,
ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells, Cancer Cell, vol.10, pp.227-239, 2006. ,
Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells, Carcinogenesis, vol.29, pp.1930-1937, 2008. ,
Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression, Exp. Cell Res, vol.314, pp.2448-2453, 2008. ,
, , 2007.
, PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition, Cancer Res, vol.67, pp.2922-2926
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug, Nat. Cell Biol, vol.11, pp.694-704, 2009. ,
Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion, Cancer Res, vol.67, pp.7184-7193, 2007. ,
Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-beta during the process of epithelial to mesenchymal transition in rat proximal epithelial cells, Biochim. Biophys. Acta, vol.1782, pp.51-59, 2008. ,
LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast Cancer, Cell, vol.138, pp.660-672, 2009. ,
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing, Mol. Cell, vol.33, pp.591-601, 2009. ,
The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events, RNA Biol, vol.6, 2009. ,
The EMTactivator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs, Nat. Cell Biol, 2009. ,
The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes, Oncogene, vol.27, pp.3875-3879, 2008. ,
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton, Cancer Cell, vol.9, pp.261-272, 2006. ,
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines, Cancer Res, vol.66, pp.944-950, 2006. ,
Ingression of primary mesenchyme cells of the sea urchin embryo: a precisely timed epithelial mesenchymal transition, Birth Defects Res. C Embryo Today, vol.81, pp.241-252, 2007. ,
Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo, Dev. Biol, vol.319, pp.406-415, 2008. ,
Stabilization of Snail by NF-?B is required for inflammation-induced cell migration and invasion, Cancer Cell, vol.15, pp.416-428, 2009. ,
Small C-terminal domain phosphatase enhances snail activity through dephosphorylation, J. Biol. Chem, vol.284, pp.640-648, 2009. ,
The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development, J. Cell Biol, vol.178, pp.1223-1235, 2007. ,
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors, Cancer Res, vol.67, pp.2649-2656, 2007. ,
Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer, Nature, vol.429, pp.298-302, 2004. ,
Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells, N. Engl. J. Med, vol.348, pp.403-413, 2003. ,
Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in human pancreatic carcinoma cells, Cancer Res, vol.66, pp.46-51, 2006. ,
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines, Clin. Cancer Res, vol.12, pp.4147-4153, 2006. ,
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis, Dev. Cell, vol.14, pp.818-829, 2008. ,
P68 RNA helicase mediates PDGFinduced epithelial mesenchymal transition by displacing Axin from betacatenin, Cell, vol.127, pp.139-155, 2006. ,
Direct regulation of TWIST by HIF-1alpha promotes metastasis, Nat. Cell Biol, vol.10, pp.295-305, 2008. ,
Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients, Clin. Cancer Res, vol.11, pp.8686-8698, 2005. ,
Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity, Cells Tissues Organs, vol.185, pp.157-161, 2007. ,
Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models, Am. J. Physiol, vol.285, pp.1060-1067, 2003. ,
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis, Nat. Med, vol.13, pp.952-961, 2007. ,
Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition, J. Biol. Chem, vol.282, pp.23337-23347, 2007. ,
Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition, J. Am. Soc. Nephrol, vol.19, pp.2282-2287, 2008. ,
Mullerian inhibiting substance regulates its receptor/SMAD signaling and causes mesenchymal transition of the coelomic epithelial cells early in Mullerian duct regression, Development, vol.133, pp.2359-2369, 2006. ,
Vascular endothelial growth factor expression in peritoneal mesothelial cells undergoing transdifferentiation, Perit. Dial. Int, vol.28, pp.497-504, 2008. ,
p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation, Cell, vol.125, pp.957-969, 2006. ,