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Efficient Synthesis of 7-Substituted or 3,7-Disubstituted 1H-Indazoles

Abstract : E f f i c i e n t S y n t h e s i s o f 7-S u b s t i t u t e d o r 3 , 7-D i s u b s t i t u t e d 1 H-I n d a z o l e s Abstract: This work reports on the synthesis of the novel indazole scaffolds 7-OTf-1H-indazole (trifluoromethanesulfonic acid 1H-indazol-7-yl ester), 7-iodo-1H-indazole and 3-bromo-7-iodo-1H-indazole. These new compounds are potent building blocks in divergent syntheses of indazoles via palladium cross-coupling reactions.
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https://hal.inrae.fr/hal-02921668
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Betty Cottyn, Dominique Vichard, François Terrier, Pierre Nioche, C. Raman. Efficient Synthesis of 7-Substituted or 3,7-Disubstituted 1H-Indazoles. SYNLETT, Georg Thieme Verlag, 2007, 2007 (08), pp.1203-1206. ⟨10.1055/s-2007-977416⟩. ⟨hal-02921668⟩

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