J. Fukami, F. J. Ollero, M. Megías, and M. Hungria, Phytohormones and induction of plant-stress tolerance and defense genes by seed and foliar inoculation with Azospirillum brasilense cells and metabolites promote maize growth, AMB Express, vol.7, p.28724262, 2017.

J. Fukami, F. J. Ollero, C. De-la-osa, R. Valderrama-ferná-ndez, M. A. Nogueira et al., Antioxidant activity and induction of mechanisms of resistance to stresses related to the inoculation with Azospirillum brasilense, Arch Microbiol, vol.200, p.29881875, 2018.

F. Cassán and M. Diaz-zorita, Azospirillum sp. in current agriculture: From the laboratory to the field, Soil Biol Biochem, vol.103, pp.117-130, 2016.

T. Carvalho, H. Ballesteros, F. Thiebaut, P. Ferreira, and A. S. Hemerly, Nice to meet you: genetic, epigenetic and metabolic controls of plant perception of beneficial associative and endophytic diazotrophic bacteria in non-leguminous plants, Plant Mol Biol, vol.90, p.26821805, 2016.

F. N. Cunha, N. F. Silva, R. Da, C. Rodrigues, A. Morais et al., Performance of different genotypes of maize subjected to inoculation with Azospirillum brasilense, African J Agric Res, vol.11, pp.3853-3862, 2016.

L. C. Brusamarello-santos, F. Gilard, L. Brulé, I. Quilleré, B. Gourion et al., Metabolic profiling of two maize (Zea mays L.) inbred lines inoculated with the nitrogen fixing plant-interacting bacteria Herbaspirillum seropedicae and Azospirillum brasilense. Aroca R, editor, PLoS One, vol.12, p.174576, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02410322

J. E. Rosas, S. Martínez, P. Blanco, P. De-vida, F. Bonnecarrère et al., Resistance to Multiple Temperate and Tropical Stem and Sheath Diseases of Rice, Plant Genome, vol.11, pp.1-13, 2017.

A. Genissel, J. Confais, M. Lebrun, and L. Gout, Association Genetics in Plant Pathogens: Minding the Gap between the Natural Variation and the Molecular Function, Front Plant Sci, vol.8, pp.8-11, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01607896

H. Lehnert, A. Serfling, M. Enders, W. Friedt, and F. Ordon, Genetics of mycorrhizal symbiosis in winter wheat (Triticum aestivum), New Phytol, vol.215, pp.779-791, 2017.

D. Vita, P. Avio, L. Sbrana, C. Laidò, G. Marone et al., Genetic markers associated to arbuscular mycorrhizal colonization in durum wheat, Sci Rep, vol.8, p.30006562, 2018.

J. G. Wallace, K. A. Kremling, L. L. Kovar, and E. S. Buckler, Maize Leaf Microbiome, Phyt. J, vol.2, pp.208-224, 2018.

K. Kamfwa, K. A. Cichy, and J. D. Kelly, Genome-wide association analysis of symbiotic nitrogen fixation in common bean, Theor Appl Genet, vol.128, p.26133733, 2015.

P. Wintermans, P. Bakker, and C. Pieterse, Natural genetic variation in Arabidopsis for responsiveness to plant growth-promoting rhizobacteria, Plant Mol Biol, vol.90, pp.623-634, 2016.

C. Pieterse, R. De-jonge, and R. L. Berendsen, The Soil-Borne Supremacy, Trends Plant Sci, vol.21, pp.171-173, 2016.

L. C. Carvalhais, P. G. Dennis, B. Fan, D. Fedoseyenko, K. Kierul et al., Linking Plant Nutritional Status to Plant-Microbe Interactions, PLoS One, vol.8, 2013.

G. Castrillo, P. Teixeira, S. H. Paredes, T. F. Law, D. Lorenzo et al., Root microbiota drive direct integration of phosphate stress and immunity, Nature, vol.543, pp.513-518, 2017.

E. A. Gomes, U. Lana, J. F. Quensen, C. A. Oliveira, J. Guo et al., Root-associated microbiome of maize genotypes with contrasting phosphorus use efficiency, Phyt. J, vol.2, pp.129-137, 2018.

J. Yang, S. Mezmouk, A. Baumgarten, E. S. Buckler, K. E. Guill et al., Incomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize, PLOS Genet, vol.13, p.1007019, 2017.

Z. Li, L. Coffey, J. Garfin, N. D. Miller, M. R. White et al., Genotype-by-environment interactions affecting heterosis in maize, PLoS One, vol.13, p.191321, 2018.

H. Li, Q. Yang, L. Gao, M. Zhang, Z. Ni et al., Identification of Heterosis-Associated stable QTLs for ear-weight-related traits in an elite maize hybrid by Zhengdan 958 Design III, Front Plant Sci, vol.8, pp.1-10, 2017.

F. Bonnafous, G. Fievet, N. Blanchet, M. C. Boniface, S. Carrère et al., Comparison of GWAS models to identify non-additive genetic control of flowering time in sunflower hybrids, Theor Appl Genet, vol.131, p.29098310, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02628425

M. M. Monir and J. Zhu, Dominance and Epistasis Interactions Revealed as Important Variants for Leaf Traits of Maize NAM Population, Front Plant Sci, vol.9, pp.1-10, 2018.

C. Picard and M. Bosco, Maize heterosis affects the structure and dynamics of indigenous rhizospheric auxins-producing Pseudomonas populations, FEMS Microbiol Ecol, vol.53, pp.349-357, 2005.

C. Picard and M. Bosco, Heterozygosis drives maize hybrids to select elite 2,4-diacethylphloroglucinol-producing Pseudomonas strains among resident soil populations, FEMS Microbiol Ecol, vol.58, p.17064261, 2006.

M. Groszmann, R. Gonzalez-bayon, R. L. Lyons, I. K. Greaves, K. Kazan et al., Hormone-regulated defense and stress response networks contribute to heterosis in Arabidopsis F1 hybrids, Proc Natl Acad Sci, vol.112, pp.6397-6406, 2015.

X. Hu, H. Wang, K. Li, Y. Wu, Z. Liu et al., Genome-wide proteomic profiling reveals the role of dominance protein expression in heterosis in immature maize ears, Sci Rep, vol.7, p.29170427, 2017.

D. K. Ko, D. Rohozinski, Q. Song, S. H. Taylor, T. E. Juenger et al., Temporal Shift of Circadian-Mediated Gene Expression and Carbon Fixation Contributes to Biomass Heterosis in Maize Hybrids, PLOS Genet, vol.12, 2016.

A. Paschold, C. Marcon, N. Hoecker, and F. Hochholdinger, Molecular dissection of heterosis manifestation during early maize root development, Theor Appl Genet, vol.120, p.19526205, 2010.

C. Planchamp, G. Glauser, and B. Mauch-mani, Root inoculation with Pseudomonas putida KT2440 induces transcriptional and metabolic changes and systemic resistance in maize plants, Front Plant Sci, vol.5, pp.1-10, 2015.

A. K. Calzavara, P. Paiva, L. C. Gabriel, A. De-oliveira, K. Milani et al., Associative bacteria influence maize (Zea mays L.) growth, physiology and root anatomy under different nitrogen levels, Plant Biol, vol.20, pp.870-878, 2018.

D. Salvo, L. P. Ferrando, L. Fernández-scavino, A. , G. De-salamone et al., Microorganisms reveal what plants do not: wheat growth and rhizosphere microbial communities after Azospirillum brasilense inoculation and nitrogen fertilization under field conditions, Plant Soil. Plant and Soil, pp.1-13, 2018.

Y. A. Tsepilov, S. Shin, N. Soranzo, T. D. Spector, C. Prehn et al., Nonadditive Effects of Genes in Human Metabolomics, Genetics, vol.200, pp.707-718, 2015.

P. Goyette, G. Boucher, D. Mallon, E. Ellinghaus, L. Jostins et al., High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis, Nat Genet, vol.47, pp.172-181, 2015.

M. Hungria, R. J. Campo, E. M. Souza, and F. O. Pedrosa, Inoculation with selected strains of Azospirillum brasilense and A. lipoferum improves yields of maize and wheat in Brazil, Plant Soil, vol.331, pp.413-425, 2010.

R. Neto, J. Malavolta, V. A. Victor, and O. , Meio simples para o isolamento e cultivo de Xanthomonas campestris pv. citri Tipo B, Summa Phytopathol, vol.12, p.32, 1986.

L. Mendonça, Í. Granato, F. C. Alves, P. Morais, M. S. Vidotti et al., Accuracy and simultaneous selection gains for N-stress tolerance and N-use efficiency in maize tropical lines, Sci Agric, vol.74, pp.481-488, 2017.

E. Lanes, J. Viana, G. P. Paes, M. Paula, C. Maia et al., Population structure and genetic diversity of maize inbreds derived from tropical hybrids, Genet Mol Res, vol.13, pp.7365-7376, 2014.

J. S. Morosini, L. Mendonça, D. H. Lyra, G. Galli, M. S. Vidotti et al., Association mapping for traits related to nitrogen use efficiency in tropical maize lines under field conditions, Plant and Soil, vol.421, pp.453-463, 2017.

M. Kox, C. Lü-ke, C. Fritz, E. Van-den-elzen, T. Van-alen et al., Effects of nitrogen fertilization on diazotrophic activity of microorganisms associated with Sphagnum magellanicum, Plant and Soil, vol.406, pp.83-100, 2016.

D. M. Zeffa, L. H. Fantin, O. Santos, A. Oliveira, . De et al., The influence of topdressing nitrogen on Azospirillum spp. inoculation in maize crops through meta-analysis. Bragantia, vol.77, pp.493-500, 2018.

M. S. Vidotti, F. I. Matias, F. C. Alves, P. Pé-rez-rodríguez, G. A. Beltran et al., Maize responsiveness to Azospirillum brasilense: Insights into genetic control, heterosis and genomic prediction, PLoS One, vol.14, p.217571, 2019.

S. Trachsel, S. M. Kaeppler, K. M. Brown, and J. P. Lynch, Maize root growth angles become steeper under low N conditions, F Crop Res, vol.140, pp.18-31, 2013.

D. G. Butler, B. R. Cullis, A. R. Gilmour, and B. J. Gogel, Analysis of Mixed Models for S-language Environments, ASReml-R Reference Manual, 2009.

C. Brien, ASReml-R" in Fitting Mixed Models. R Packag Version 20-12

S. Unterseer, E. Bauer, G. Haberer, M. Seidel, C. Knaak et al., A powerful tool for genome analysis in maize: development and evaluation of the high density 600 k SNP genotyping array, BMC Genomics, vol.15, p.25266061, 2014.

B. L. Browning and S. R. Browning, Genotype Imputation with Millions of Reference Samples, Am J Hum Genet, vol.98, pp.116-126, 2016.

X. Zheng, D. Levine, J. Shen, S. M. Gogarten, C. Laurie et al., A high-performance computing toolset for relatedness and principal component analysis of SNP data, Bioinformatics, vol.28, pp.3326-3328, 2012.

X. Liu, M. Huang, B. Fan, E. S. Buckler, and Z. Zhang, Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies, PLoS Genet, vol.12, p.100, 2016.

S. Purcell, B. Neale, K. Todd-brown, L. Thomas, M. Ferreira et al., PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses, Am J Hum Genet, vol.81, pp.559-575, 2007.

H. Chen and P. C. Boutros, VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R, BMC Bioinformatics, vol.12, p.35, 2011.

M. Ashburner, C. A. Ball, J. A. Blake, D. Botstein, H. Butler et al., Gene Ontology: tool for the unification of biology, Nat Genet, vol.25, pp.25-29, 2000.

A. Conesa, S. Gotz, J. M. Garcia-gomez, J. Terol, M. Talon et al., Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research, Bioinformatics, vol.21, pp.3674-3676, 2005.

C. Rozier, A. Erban, J. Hamzaoui, C. Prigent-combaret, G. Comte et al., Xylem Sap Metabolite Profile Changes During Phytostimulation of Maize by the Plant Growth-Promoting Rhizobacterium, Azospirillum lipoferum CRT1, J Postgenomics Drug Biomark Dev, vol.6, pp.1-10, 2016.
URL : https://hal.archives-ouvertes.fr/hal-02466009

D. M. Zeffa, L. J. Perini, M. B. Silva, N. V. De-sousa, C. A. Scapim et al., Azospirillum brasilense promotes increases in growth and nitrogen use efficiency of maize genotypes, PLoS One, vol.14, p.215332, 2019.

A. C. Cohen, C. N. Travaglia, R. Bottini, and P. N. Piccoli, Participation of abscisic acid and gibberellins produced by endophytic Azospirillum in the alleviation of drought effects in maize, Botany, vol.87, pp.455-462, 2009.

V. Walker, C. Bertrand, F. Bellvert, Y. Moënne-loccoz, R. Bally et al., Host plant secondary metabolite profiling shows a complex, strain-dependent response of maize to plant growth-promoting rhizobacteria of the genus Azospirillum, New Phytol, vol.189, p.20946131, 2011.
URL : https://hal.archives-ouvertes.fr/halsde-00529161

C. Rozier, J. Hamzaoui, D. Lemoine, S. Czarnes, and L. Legendre, Field-based assessment of the mechanism of maize yield enhancement by Azospirillum lipoferum CRT1, Sci Rep, vol.7, pp.1-12, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01608505

M. R. Martins, C. P. Jantalia, V. M. Reis, I. Döwich, J. C. Polidoro et al., Impact of plant growth-promoting bacteria on grain yield, protein content, and urea-15 N recovery by maize in a Cerrado Oxisol, Plant and Soil, vol.422, pp.239-250, 2018.

J. A. Curá, D. R. Franz, J. E. Filosofía, K. B. Balestrasse, and L. E. Burgueño, Inoculation with Azospirillum sp. and Herbaspirillum sp. bacteria increases the tolerance of maize to drought stress, Microorganisms, vol.5, p.41, 2017.

S. Spaepen, S. Bossuyt, K. Engelen, K. Marchal, and J. Vanderleyden, Phenotypical and molecular responses of Arabidopsis thaliana roots as a result of inoculation with the auxin-producing bacterium Azospirillum brasilense, New Phytol, vol.201, pp.850-861, 2014.

A. Chamam, F. Wisniewski-dyé, G. Comte, C. Bertrand, and C. Prigent-combaret, Differential responses of Oryza sativa secondary metabolism to biotic interactions with cooperative, commensal and phytopathogenic bacteria, Planta, vol.242, pp.1439-1452, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01211739

M. Gopal and A. Gupta, Microbiome selection could spur next-generation plant breeding strategies, Front Microbiol, vol.7, pp.1-10, 2016.

P. Hohmann and M. M. Messmer, Breeding for mycorrhizal symbiosis: focus on disease resistance, Euphytica, vol.213, pp.1-11, 2017.

A. Nogales, T. Nobre, V. Valadas, C. Ragonezi, M. Dö-ring et al., Can functional hologenomics aid tackling current challenges in plant breeding?, Brief Funct Genomics, vol.1, pp.288-297, 2016.

J. Fukami, M. A. Nogueira, R. S. Araujo, and M. Hungria, Accessing inoculation methods of maize and wheat with Azospirillum brasilense, AMB Express, vol.6, 2016.

A. Rosier, U. Bishnoi, V. Lakshmanan, D. J. Sherrier, and H. P. Bais, A perspective on inter-kingdom signaling in plant-beneficial microbe interactions, Plant Mol Biol, vol.90, pp.537-548, 2016.

P. H. Fesel and A. Zuccaro, Dissecting endophytic lifestyle along the parasitism/mutualism continuum in Arabidopsis, Curr Opin Microbiol, vol.32, pp.103-112, 2016.

B. Schulz and C. Boyle, The endophytic continuum, Mycol Res, vol.109, pp.661-686, 2005.

M. A. German, S. Burdman, Y. Okon, and J. Kigel, Effects of Azospirillum brasilense on root morphology of common bean (Phaseolus vulgaris L.) under different water regimes, Biol Fertil Soils, vol.32, pp.259-264, 2000.

D. R. Duca, D. R. Rose, and B. R. Glick, Indole acetic acid overproduction transformants of the rhizobacterium Pseudomonas sp. UW4. Antonie Van Leeuwenhoek, vol.111, p.29492769, 2018.

C. Wang, W. Liu, Q. Li, D. Ma, H. Lu et al., Effects of different irrigation and nitrogen regimes on root growth and its correlation with above-ground plant parts in high-yielding wheat under field conditions, F Crop Res, vol.165, pp.138-149, 2014.

W. Xu, K. Cui, A. Xu, L. Nie, J. Huang et al., Drought stress condition increases root to shoot ratio via alteration of carbohydrate partitioning and enzymatic activity in rice seedlings, Acta Physiol Plant, vol.37, 2015.

J. Yan, M. Warburton, and J. Crouch, Association Mapping for Enhancing Maize (L.) Genetic Improvement, Crop Sci, vol.51, p.433, 2011.

A. Korte and A. Farlow, The advantages and limitations of trait analysis with GWAS: a review, Plant Methods, vol.9, 2013.

H. Wang, C. Xu, X. Liu, Z. Guo, X. Xu et al., Development of a multiple-hybrid population for genome-wide association studies: theoretical consideration and genetic mapping of flowering traits in maize, Sci Rep, vol.7, p.40239, 2017.

S. U. Huh and K. Paek, Plant RNA binding proteins for control of RNA virus infection, Front Physiol, vol.4, pp.1-5, 2013.

P. Cheng, C. R. Gedling, G. Patil, T. D. Vuong, J. G. Shannon et al., Genetic mapping and haplotype analysis of a locus for quantitative resistance to Fusarium graminearum in soybean accession PI 567516C, Theor Appl Genet, vol.130, p.28275816, 2017.

I. Klay, S. Gouia, M. Liu, M. I. Khoudi, H. Bernadac et al., Ethylene Response Factors (ERF) are differentially regulated by different abiotic stress types in tomato plants, Plant Sci, vol.274, pp.137-145, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02626871

X. Sun, G. Yu, J. Li, J. Liu, X. Wang et al., AcERF2, an ethylene-responsive factor of Atriplex canescens, positively modulates osmotic and disease resistance in Arabidopsis thaliana, Plant Sci, vol.274, pp.32-43, 2018.

A. Rai, S. Kumar, K. Bauddh, N. Singh, and R. P. Singh, Improvement in growth and alkaloid content of Rauwolfia serpentina on application of organic matrix entrapped biofertilizers (Azotobacter chroococcum, Azospirillum brasilense and Pseudomonas putida), J Plant Nutr, vol.40, pp.2237-2247, 2017.

N. D. Tivendale, J. J. Ross, and J. D. Cohen, The shifting paradigms of auxin biosynthesis, Trends Plant Sci, vol.19, pp.44-51, 2014.

Y. Wang, G. Yuan, S. Yuan, W. Duan, P. Wang et al., TaOPR2 encodes a 12-oxo-phytodienoic acid reductase involved in the biosynthesis of jasmonic acid in wheat (Triticum aestivum L.), Biochem Biophys Res Commun, vol.470, pp.233-238, 2016.

A. J. Koo, Metabolism of the plant hormone jasmonate: a sentinel for tissue damage and master regulator of stress response, Phytochem Rev, vol.17, pp.51-80, 2018.

M. Dicke, Plant phenotypic plasticity in the phytobiome: a volatile issue, Curr Opin Plant Biol, vol.32, pp.17-23, 2016.

R. Sharifi, S. Lee, and C. Ryu, Microbe-induced plant volatiles, New Phytol, vol.220, pp.684-691, 2017.

J. O. Disi, S. Zebelo, J. W. Kloepper, and H. Fadamiro, Seed inoculation with beneficial rhizobacteria affects European corn borer (Lepidoptera: Pyralidae) oviposition on maize plants, Entomol Sci, vol.21, pp.48-58, 2018.

Y. Ding, A. Huffaker, T. G. Kö-llner, P. Weckwerth, C. Robert et al., Selinene Volatiles Are Essential Precursors for Maize Defense Promoting Fungal Pathogen Resistance, Plant Physiol, vol.175, pp.1455-1468, 2017.

J. C. D'auria, E. Pichersky, A. Schaub, A. Hansel, and J. Gershenzon, Characterization of a BAHD acyltransferase responsible for producing the green leaf volatile (Z)-3-hexen-1-yl acetate in Arabidopsis thaliana, Plant J, vol.49, p.17163881, 2007.

L. Liu, U. Ludewig, B. Gassert, W. Frommer, N. Wirén et al., Urea Transport by Nitrogen-Regulated Tonoplast Intrinsic Proteins in Arabidopsis, Plant Physiol, vol.133, pp.1220-1228, 2003.

L. Ding, Z. Lu, L. Gao, S. Guo, and Q. Shen, Is Nitrogen a Key Determinant of Water Transport and Photosynthesis in Higher Plants Upon Drought Stress?, Front Plant Sci, vol.9, pp.1-12, 2018.

K. Kishor and P. B. , Role of proline in cell wall synthesis and plant development and its implications in plant ontogeny, Front Plant Sci, vol.6, pp.1-17, 2015.

E. Nguema-ona, M. Vicré--gibouin, M. Cannesan, and A. Driouich, Arabinogalactan proteins in rootmicrobe interactions, Trends Plant Sci, vol.18, pp.440-449, 2013.
URL : https://hal.archives-ouvertes.fr/hal-01843944

Y. Oda and S. Hasezawa, Cytoskeletal organization during xylem cell differentiation, J Plant Res, vol.119, pp.167-177, 2006.

L. Ding, K. J. Wang, G. M. Jiang, D. K. Biswas, H. Xu et al., Effects of Nitrogen Deficiency on Photosynthetic Traits of Maize Hybrids Released in Different Years, Ann Bot, vol.96, pp.925-930, 2005.

C. M. Timm, D. A. Pelletier, S. S. Jawdy, L. E. Gunter, J. A. Henning et al., Two Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System, Plant Sci, vol.7, issue.10, 2016.

B. Luo, H. Tang, H. Liu, S. Shunzong, S. Zhang et al., Mining for low-nitrogen tolerance genes by integrating meta-analysis and large-scale gene expression data from maize, Euphytica, vol.206, pp.117-131, 2015.

E. M?odzi?ska, G. K?obus, M. D. Christensen, and A. T. Fuglsang, The plasma membrane H + -ATPase AHA2 contributes to the root architecture in response to different nitrogen supply, Physiol Plant, vol.154, pp.270-282, 2015.

S. M. Velasquez, M. M. Ricardi, J. G. Dorosz, P. V. Fernandez, A. D. Nadra et al., O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth, Science, vol.332, pp.1401-1403, 2011.

M. Khan, A. Trivellini, M. Fatma, A. Masood, A. Francini et al., Role of ethylene in responses of plants to nitrogen availability, Front Plant Sci, vol.6, pp.1-15, 2015.

D. Ristova, C. Carré, M. Pervent, A. Medici, G. J. Kim et al., Combinatorial interaction network of transcriptomic and phenotypic responses to nitrogen and hormones in the Arabidopsis thaliana root, Sci Signal, vol.9, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01595027

M. A. Abri, C. Posbergh, K. Palermo, N. B. Sutter, J. Eberth et al., Genome-Wide Scans Reveal a Quantitative Trait Locus for Withers Height in Horses Near the ANKRD1 Gene, J Equine Vet Sci, vol.60, pp.67-73, 2018.

Y. Lee, D. Shin, and K. Song, Dominance effects of ion transport and ion transport regulator genes on the final weight and backfat thickness of Landrace pigs by dominance deviation analysis, Genes Genomics, vol.40, p.30136073, 2018.

S. Tsairidou, A. R. Allen, R. Pong-wong, S. H. Mcbride, D. M. Wright et al., An analysis of effects of heterozygosity in dairy cattle for bovine tuberculosis resistance, Anim Genet, vol.49, pp.103-109, 2018.