Aging: A Theory Based on Free Radical and Radiation Chemistry, Journal of Gerontology, vol.11, issue.3, pp.298-300, 1956. ,
Effects of Ionizing Radiation on Biological Molecules?Mechanisms of Damage and Emerging Methods of Detection, Antioxidants & Redox Signaling, vol.21, issue.2, pp.260-292, 2014. ,
Radiation induced peroxidative damage: mechanism and significance, Indian Journal of Experimental Biology, vol.39, issue.4, pp.291-309, 2001. ,
Lipid peroxidation in Rheumatoid arthritis; consequences and monitoring, Free Radical Biology and Medicine, vol.75, issue.2, p.S49, 2014. ,
Factors affecting DNA damage caused by lipid hydroperoxides and aldehydes, Free Radical Biology and Medicine, vol.20, issue.2, pp.225-236, 1996. ,
Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells, Frontiers in Oncology, vol.2, p.102, 2012. ,
The influence of redox status on inter-individual variability in the response of human peripheral blood lymphocytes to ionizing radiation, International Journal of Radiation Biology, vol.94, issue.6, pp.569-575, 2018. ,
Inter-individual variability in the response of human peripheral blood lymphocytes to ionizing radiation: comparison of the dicentric and micronucleus assays, Radiation and Environmental Biophysics, vol.54, issue.3, pp.317-325, 2015. ,
Analyses of Ionizing Radiation EffectsIn Vitroin Peripheral Blood Lymphocytes with Raman Spectroscopy, Radiation Research, vol.183, issue.4, pp.407-416, 2015. ,
Aging and radiation: bad companions, Aging Cell, vol.14, issue.2, pp.153-161, 2015. ,
Rate of individuals with clearly increased radiosensitivity rise with age both in healthy individuals and in cancer patients, BMC Geriatrics, vol.18, issue.1, p.105, 2018. ,
Radioprotection by Antioxidantsa, Annals of the New York Academy of Sciences, vol.899, issue.1, pp.44-60, 2006. ,
Protection against ionizing radiation by antioxidant nutrients and phytochemicals, Toxicology, vol.189, issue.1-2, pp.1-20, 2003. ,
Radio-protective role of antioxidant agents, Oncology Reviews, vol.6, issue.2, p.e16, 2012. ,
Radioprotective agents to prevent cellular damage due to ionizing radiation, Journal of Translational Medicine, vol.15, issue.1, p.232, 2017. ,
, Oxidative Medicine and Cellular Longevity, Oxidative Medicine and Cellular Longevity
Effects of antioxidant supplementation on the aging process, Clinical Interventions in Aging, vol.2, issue.3, pp.377-387, 2007. ,
Role of antioxidants in the skin: Anti-aging effects, Journal of Dermatological Science, vol.58, issue.2, pp.85-90, 2010. ,
Effect of Antioxidants Supplementation on Aging and Longevity, BioMed Research International, vol.2014, pp.1-17, 2014. ,
Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1573, issue.2, pp.109-120, 2002. ,
Competitive Action of Calcium and Procaine on Lobster Axon, Journal of General Physiology, vol.49, issue.5, pp.1043-1063, 1966. ,
Membrane Stabilization by Drugs: Tranquilizers, Steroids, and Anesthetics, International Review of Neurobiology, vol.24, pp.145-221, 1966. ,
Effects of anesthetics on mitochondrial signaling and function, Current Drug Safety, vol.7, issue.2, pp.126-139, 2012. ,
Effects of procaine on the oxidative phosphorylation of brain mitochondria from senescent rats, Mechanisms of Ageing and Development, vol.26, issue.2-3, pp.277-282, 1984. ,
A comparative study of the effects of procaine, lidocaine, tetracaine and dibucaine on the functions and ultrastructure of isolated rat liver mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1019, issue.1, pp.19-28, 1990. ,
Procaine HCl (Gerovital H3): A weak, reversible, fully competitive inhibitor of monoamine oxidase, Biology of Aging and Development, vol.34, pp.213-218, 1975. ,
DNA Demethylating Agents and Chromatin-Remodelling Drugs: Which, How and Why?, Current Drug Metabolism, vol.4, issue.1, pp.22-31, 2003. ,
The Reappearance of Procaine Hydrochloride (Gerovital H3) for Antiaging, Journal of the American Geriatrics Society, vol.61, issue.6, pp.1024-1025, 2013. ,
The Systemic Use of Procaine in the Treatment of the Elderly: A Review?, Journal of the American Geriatrics Society, vol.25, issue.1, pp.1-19, 1977. ,
Antioxidant effect of lidocaine and procaine on reactive oxygen species-induced endothelial dysfunction in the rabbit abdominal aorta, Korean Journal of Anesthesiology, vol.59, issue.2, p.104, 2010. ,
Gerovital H3 ? biochemical mechanism involved in antioxidant action, Farmacist.ro, vol.1, issue.174, pp.761-766, 2017. ,
Inhibitory effect of procaine, Gerovital H3 and Aslavital on the production of superoxide radical, Romanian Journal of Gerontology and Geriatrics, vol.10, issue.2, pp.117-129, 1989. ,
Effect of procaine hydrochloride on DNA repair in Escherichia coli, Chemico-Biological Interactions, vol.11, issue.3, pp.173-178, 1975. ,
A modified and automated version of the 'Fluorimetric Detection of Alkaline DNA Unwinding' method to quantify formation and repair of DNA strand breaks, BMC Biotechnology, vol.9, issue.1, p.39, 2009. ,
The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage, ALTEX, vol.28, issue.4, pp.295-303, 2011. ,
Upregulation of miR?24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8 + T cells sensitizing them to apoptotic cell death, Aging Cell, vol.11, issue.4, pp.579-587, 2012. ,
DNA damage-independent apoptosis induced by curcumin in normal resting human T cells and leukaemic Jurkat cells, Mutagenesis, vol.28, issue.4, pp.411-416, 2013. ,
Corrigendum to ?Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of human resting T cells? [DNA Repair 11 (11) (2012) 864?873], DNA Repair, vol.12, issue.10, p.872, 2013. ,
Genetic and environmental influence on DNA strand break repair: A twin study, Environmental and Molecular Mutagenesis, vol.54, issue.6, pp.414-420, 2013. ,
Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients, Aging, vol.7, issue.10, pp.793-810, 2015. ,
Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance, Acta Physiologica, vol.213, issue.1, pp.156-170, 2014. ,
Effects of Psychotherapy on DNA Strand Break Accumulation Originating from Traumatic Stress, Psychotherapy and Psychosomatics, vol.83, issue.5, pp.289-297, 2014. ,
Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells, International Journal of Molecular Sciences, vol.19, issue.11, p.3689, 2018. ,
The degree of radiation-induced DNA strand breaks is altered by acute sleep deprivation and psychological stress and is associated with cognitive performance in humans, Sleep, vol.41, issue.7, 2018. ,
The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes, PLoS ONE, vol.9, issue.8, p.e104964, 2014. ,
Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors, Aging, vol.7, issue.2, pp.110-122, 2015. ,
Day and night variations in the repair of ionizing-radiation-induced DNA damage in mouse splenocytes, DNA Repair, vol.28, pp.37-47, 2015. ,
, Oxidative Medicine and Cellular Longevity, Oxidative Medicine and Cellular Longevity
Impaired PARP activity in response to the ?-adrenergic receptor agonist isoproterenol, Toxicology in Vitro, vol.50, pp.29-39, 2018. ,
Mathematical modelling of the automated FADU assay for the quantification of DNA strand breaks and their repair in human peripheral mononuclear blood cells, BMC Biophysics, vol.7, issue.1, p.9, 2014. ,
Membranar effects exerted in vitro by polyphenols ? quercetin, epigallocatechin gallate and curcumin ? on HUVEC and Jurkat cells, relevant for diabetes mellitus, Food and Chemical Toxicology, vol.61, pp.86-93, 2013. ,
Assessment of the potential health benefits of certain total extracts from Vitis vinifera, Aesculus hyppocastanum and Curcuma longa, Experimental and Therapeutic Medicine, vol.10, issue.5, pp.1681-1688, 2015. ,
Lipoprotein redox status evaluation as a marker of cardiovascular disease risk in patients with inflammatory disease, Molecular Medicine Reports, vol.15, issue.1, pp.256-262, 2016. ,
Preclinical and clinical results regarding the effects of a plant-based antidiabetic formulation versus well established antidiabetic molecules, Pharmacological Research, vol.150, p.104522, 2019. ,
Spectrophotometric versus spectrofluorometric assessment in the study of the relationships between lipid peroxidation and metabolic dysregulation, Chemical Biology & Drug Design, vol.93, issue.6, pp.1026-1035, 2019. ,
Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells, Nature Protocols, vol.4, issue.11, pp.1582-1590, 2009. ,
Adiponectin: possible link between metabolic stress and oxidative stress in the elderly, Aging Clinical and Experimental Research, vol.29, issue.4, pp.621-629, 2016. ,
In vitro free radical scavenging capacity of thyroid hormones and structural analogues, Journal of Endocrinology, vol.170, issue.1, pp.197-206, 2001. ,
Thyroid hormone (T3) and its acetic derivative (TA3) protect low-density lipoproteins from oxidation by different mechanisms, Biochimie, vol.86, issue.6, pp.411-418, 2004. ,
Inhibition of in vitro macrophage-induced low density lipoprotein oxidation by thyroid compounds, Journal of Endocrinology, vol.177, issue.1, pp.137-146, 2003. ,
DNA Damage: A Main Determinant of Vascular Aging, International Journal of Molecular Sciences, vol.17, issue.5, p.748, 2016. ,
A study on effect of ageing on the levels of total antioxidant and lipid peroxidation, International Journal of Contemporary Medical Research, vol.4, issue.12, pp.8-10, 2017. ,
DNA damage and ageing: new-age ideas for an age-old problem, Nature Cell Biology, vol.10, issue.11, pp.1241-1247, 2008. ,
Changes in DNA repair during aging, Nucleic Acids Research, vol.35, issue.22, pp.7466-7474, 2007. ,
The role of DNA damage and repair in aging through the prism of Koch-like criteria, Ageing Research Reviews, vol.12, issue.2, pp.661-684, 2013. ,
Ionising radiation and cancer risks: What have we learned from epidemiology?, International Journal of Radiation Biology, vol.85, issue.6, pp.467-482, 2009. ,
Enzymatic Processing of Radiation-Induced Free Radical Damage in DNA, Radiation Research, vol.150, issue.5, p.S60, 1998. ,
An investigation of antioxidant status, DNA repair capacity and mutation as a function of age in humans, Mutation Research/DNAging, vol.338, issue.1-6, pp.115-128, 1995. ,
Regulation of quiescence in lymphocytes, Trends in Immunology, vol.24, issue.7, pp.380-386, 2003. ,
Effect of age on sensitivity of human lymphocytes to radiation. A brief note, Mechanisms of Ageing and Development, vol.19, issue.2, pp.97-101, 1982. ,
Individual Radiosensitivity and its Relevance to Health Physics, Dose-Response, vol.5, issue.4, pp.dose-response.0, 2007. ,
Intrinsic susceptibility to radiation-induced apoptosis of human lymphocyte subpopulations, International Journal of Radiation Oncology*Biology*Physics, vol.57, issue.3, pp.769-778, 2003. ,
Radiation-induced apoptosis varies among individuals and is modified by sex and age, International Journal of Radiation Biology, vol.90, issue.10, pp.903-908, 2014. ,
Induction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animals, Aging, vol.3, issue.6, pp.609-620, 2011. ,
DNA damage and rpair with age in individual human lymphocytes, Mutation Research/DNAging, vol.237, issue.3-4, pp.123-130, 1990. ,
Effect of aging on formation of reactive oxygen species by?mitochondria of?rat heart, General physiology and biophysics, vol.32, issue.03, pp.415-420, 2014. ,
Oxidized LDL and NO synthesis?Biomarkers of endothelial dysfunction and ageing, Mechanisms of Ageing and Development, vol.151, pp.101-113, 2015. ,
The Effects of a European Procaine Preparation in an Aged Population, Journal of Gerontology, vol.20, issue.2, pp.144-150, 1965. ,
Aslan-Therapie mit Gero-H3 -Aslan, Zeitschrift für Allgemeinmedizin, vol.60, issue.27, pp.1162-1164, 1984. ,