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Master thesis

La diversification génétique et des pratiques dans le pilotage de la santé des lapins evalué par un défi vaccinal

Abstract : Rabbits are among the farmed species that receive the higher amounts of antibiotic treatment per kilogram of live weight. However, antibiotic resistance is now a global public health problem and this method of production is no longer suitable for consumers. Therefore, it’s necessary to think about production systems which are less dependent on antibiotics and more respectful the environment and of animal welfare. Based on the principles of agroecology, this study focused on vaccine stress to analyze the robustness of INRA and cross-breeds (INRA and Fauve de Bourgogne), subjected to a diversity of feeding and adoption strategies. Myxomatosis and rabbit hemorrhagic disease (VHD) vaccine was used in a vaccine stress. A milliliter of blood sample was taken from 82 rabbits before vaccination, and at 24 and 48 hours after vaccination. Statistical analyses of the rabbit blood cells count showed that there was a significant increase in neutrophil count between 24 and 48h for all INRAs (54.5%), greater than the Crossbreeds (41%) (P<0.05) and a significant decrease in the number of monocytes of INRAs compared to the Crossbreeds (8.9% vs. 11.5% respectively) in the modality close to the conventional breeding system. However, when INRA were raised in very diverse environments, there was no significant difference noted for all the different leukocytes over time. This study constitutes an exploratory approach to reduce antibiotics in the farms. It emphasizes (i) that vaccination is a mean of assessing the robustness of growing rabbits while respecting animal welfare, and that (ii) genetic mixing, diversification of breeding practices and cross fostering could improve the overall health of the herd.
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https://hal.inrae.fr/hal-03152690
Contributor : Davi Savietto <>
Submitted on : Thursday, February 25, 2021 - 5:48:50 PM
Last modification on : Friday, June 4, 2021 - 2:40:20 PM
Long-term archiving on: : Wednesday, May 26, 2021 - 7:17:31 PM

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Linda Traore. La diversification génétique et des pratiques dans le pilotage de la santé des lapins evalué par un défi vaccinal. Sciences du Vivant [q-bio]. 2020. ⟨hal-03152690⟩

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