Tactics of host manipulation by intracellular effectors from plant pathogenic fungi
Résumé
Fungal pathogens can secrete hundreds of effectors, some of which are known to promote host susceptibility. This biological complexity, together with the lack of genetic tools in some fungi, presents a substantial challenge to develop a broad picture of the mechanisms these pathogens use for host manipulation. Nevertheless, recent advances in understanding individual effector functions are beginning to flesh out our view of fungal pathogenesis. This review discusses some of the latest findings that illustrate how effectors from diverse species use similar strategies to modulate plant physiology to their advantage. We also summarize recent breakthroughs in the identification of effectors from challenging systems, like obligate biotrophs, and emerging concepts such as the 'iceberg model' to explain how the activation of plant immunity can be turned off by effectors with suppressive activity.
Mots clés
Effector
Fungi
Host
Recognition
Immunity
Plant. Abbreviations Avr
avirulence
bZIP
basic leucine zipper
DON
deoxynivalenol
EAR
ethylene-responsive element binding factor-associated amphiphilic repression
EBE
effector binding element
ER
endoplasmic reticulum
ERF
ethylene response factor
ETI
effector-triggered immunity
HMA
heavy metal associated
HR
hypersensitive response
ID
integrated domain
JA/ET
jasmonate/ethylene
MAPK
mitogen-activated protein kinase
MAX
Magnaporthe Avrs and ToxB-like effectors
NIS1
necrosis-inducing secreted protein 1
NLR
nucleotide-binding site leucine-rich repeat receptor
PAMP
pathogen-associated molecular pattern
PM
plasma membrane
PRR
pattern recognition receptor
PTI
PAMP-triggered immunity
R
resistance
RLP
receptor-like protein
ROS
reactive oxygen species
SA
salicylic acid
SCF
Skp1-Cullin-F-box
SnRK1
SNF1-related kinase
TPL/TPR
TOPLESS/ TOPLESS related
Domaines
Biochimie, Biologie Moléculaire
Fichier principal
Figueroa, Ortiz and Henningsen 2021. Host manipulation by intracellular effectors in fungi.pdf (1.18 Mo)
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Origine : Fichiers produits par l'(les) auteur(s)
