Early experiences, including prenatal environment, are known to influence a wide variety of mechanismsinvolved in the phenotype elaboration. We investigated the effect of the addition of endocrine disruptorsor of a methyltransferase inhibitor during the embryonic development of quails from different genetic backgrounds (four different quail lines) on their growth and egg-laying performances. Fifty-four pairsof parents per line were used and fertilised eggs from each pair were randomly divided into five groups: a control group without any injection, an injected control group treated by injection into the egg ofsesame oil, and three groups treated by injection of Genistein, Bisphenol A or 5-Aza-20 -deoxycytidine. All quails were individually weighed at 8, 21, 36 and 78 days. The age at first egg laid and the numberof eggs laid were recorded. These analyses revealed a significant impact of the treatment on growth but no influence on the egg-laying traits. All three molecules significantly affected at least one of the anal- ysed growth traits. In conclusion, we showed that the injection of endocrine disruptors or DNA methyl- transferase inhibitor into the egg had significant effects on quail development; these effects were specificto each treatment, but no interaction between line and treatment was observed.