Comparative Analysis of agr Locus Diversification and Overall Genetic Variability among Bovine and Human Staphylococcus aureus Isolates - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Journal of Clinical Microbiology Year : 2004

Comparative Analysis of agr Locus Diversification and Overall Genetic Variability among Bovine and Human Staphylococcus aureus Isolates

Abstract

ABSTRACT The accessory gene regulator ( agr ) is a central system that controls the expression of Staphylococcus aureus virulence factors. In this study, the distribution of agr alleles, defined by agr restriction fragment length polymorphism within agr interference groups, among S. aureus isolates from bovine and human origin was measured with PCR-based techniques. Statistically highly significant associations of some agr alleles with the infection of a specific host were found. The genetic difference between the two S. aureus populations was further stressed after analysis of their genetic background by binary typing.

Dates and versions

hal-03672918 , version 1 (19-05-2022)

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Philippe Gilot, Willem van Leeuwen. Comparative Analysis of agr Locus Diversification and Overall Genetic Variability among Bovine and Human Staphylococcus aureus Isolates. Journal of Clinical Microbiology, 2004, 42 (3), pp.1265-1269. ⟨10.1128/JCM.42.3.1265-1269.2004⟩. ⟨hal-03672918⟩
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