Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia - Archive ouverte HAL Access content directly
Journal Articles Neuron Year : 2021

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

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Chao Wang
  • Function : Author
Monica Xiong
  • Function : Author
Maud Gratuze
Xin Bao
  • Function : Author
Yang Shi
  • Function : Author
Prabhakar Sairam Andhey
  • Function : Author
Melissa Manis
  • Function : Author
Caitlin Schroeder
  • Function : Author
Zhuoran Yin
  • Function : Author
Charlotte Madore
Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Oleg Butovsky
  • Function : Author
Maxim Artyomov
  • Function : Author
Jason Ulrich
  • Function : Author
David Holtzman
  • Function : Author

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Life Sciences [q-bio]

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https://hal.inrae.fr/hal-03704620

Submitted on : Saturday, June 25, 2022-11:13:23 AM

Last modification on : Thursday, February 2, 2023-4:53:49 PM

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hal-03704620 , version 1 (25-06-2022)

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Chao Wang, Monica Xiong, Maud Gratuze, Xin Bao, Yang Shi, et al.. Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia. Neuron, 2021, 109 (10), pp.1657-1674.e7. ⟨10.1016/j.neuron.2021.03.024⟩. ⟨hal-03704620⟩

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