In Vitro Evolution of Listeria monocytogenes Reveals Selective Pressure for Loss of SigB and AgrA Function at Different Incubation Temperatures
Résumé
To withstand environmental aggressions, L. monocytogenes upregulates a large regulon through the action of the alternative sigma factor B (σ B ). However, σ B becomes detrimental for L. monocytogenes growth under mild stresses, which confer a competitive advantage to σ B loss-of-function alleles.