This brief contains the data needed to calculate and assess the robustness of a water level – flood link (WAFL) in the Cambodian Mekong Delta, which was used to analyze changes in the long-term behavior of Monsoon inundations in the region. The data comprises the WAFL raster (.tif) files for two zones in the delta. Zone A is located on the right bank of the Bassac River, a distributary of the Mekong. Zone B is bracketed between the Mekong River and the Bassac River. The WAFL was calculated by linking water levels measured by the Mekong River Commission (MRC) at the hydrological station in Koh Khel, with inundation maps derived from Sentinel-1 and -2 images taken between 2017 and 2021. The final WAFL raster files provides a basis for estimating inundation extents using in-situ water levels. Furthermore, this brief includes data used for the assessment of WAFL, including in-situ water level data and the extents of natural vegetation in the case study area in 1990, 2000, 2010 and 2020. The former was collected using a differential pressure logger. The latter was calculated from historical Landsat image composites. Finally, raster files representing the incidence and duration of inundations in the case study area before and after the year 2008 are provided. These were calculated based on the WAFL and the MRC water levels. For each area, before- and after-images are available, as well as a raster representing the change between the two. To simplify visualization and geographical location, shapefiles (.shp) of the study area and the location of the in-situ logger are also provided.