Hypnotherapy in Treatment of Mastocytosis: A Prospective Study - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles International Journal of Clinical and Experimental Hypnosis Year : 2021

Hypnotherapy in Treatment of Mastocytosis: A Prospective Study

Abstract

Mastocytosis is an orphan disease associated with many systemic symptoms, chronic handicap, and potentially marked social consequences despite improved therapies. In this study, the authors aimed to measure the effect of 2 hypnosis sessions on mastocytosis symptoms in a clinical setting. Questionnaires (pain, flushes, energy, digestive symptoms, quality of life, perceived symptom severity, and global impression of change) were completed pre- and posthypnosis intervention. Data from 20 patients were analyzed (mean age: 53.3 years, 75% female). Compared to baseline assessment, patients exhibited a significant improvement immediately after the first and second hypnosis sessions with regard to the number of days with abdominal pain, abdominal pain intensity and fatigue (p = .03 and p = .005; p = .05 and p = .02; p = .034, and p = .039, respectively). Perceived severity of symptoms was significantly improved throughout the study (p = .0075). Long-term improvement in global impression of change was observed in half the responders (8/16). Patients with mastocytosis had an improvement in disabling symptoms with the impact of hypnotic intervention persisting at 1 month. Several patients experienced long-term improvement.

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Dates and versions

hal-03770151 , version 1 (06-09-2022)

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Frédérique Retornaz, Michel Grino, Audrey Vanhaudenhuyse, Laurent Chiche, Chloé Stavris, et al.. Hypnotherapy in Treatment of Mastocytosis: A Prospective Study. International Journal of Clinical and Experimental Hypnosis, 2021, 69 (4), pp.468-482. ⟨10.1080/00207144.2021.1965484⟩. ⟨hal-03770151⟩
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