The strength of trophic and non-trophic interactions in predator-prey dynamics may be modified by predator density/diversity and prey size characteristics. In aquatic environments, multi-dimensional scaling of search areas (water depth and surface area) may mediate interactions among predators, with implications for prey risk. Here, we used a comparative functional response (FR) approach to investigate the effects of search area, predator composition and prey size on the strength of trophic and non-trophic interactions in freshwater habitats. A model system comprising two predatory notonectids (Anisops breddini and Anisops sardeus) was examined consuming four larval instar prey of Culex quinquefasciatus mosquitoes at nine different arena sizes, consisting of three crossed levels of surface area and water depth. Type II FRs were most common among predator groups, with 2nd instar prey consumed the most overall. Here, A. sardeus exhibited significantly higher feeding rates as compared to A. breddini, particularly in shallow waters. Non-trophic interactions in conspecific A. breddini and heterospecific pairs were mostly negative, indicating reduced prey risk. Further, predator-predator antagonisms were most pronounced in the heterospecific pairs. Strength of trophic and nontrophic interactions is thus dependent on complex interplays between the characteristics of predatorprey participants in combination with environmental heterogeneities.