Updates for Goat SNP Chips
Résumé
The third update of the Illumina Goat SNP chip represents a significant advancement in the genomic tools available for goat breeding and genetic research. This updated SNP chip incorporates a comprehensive array of 78491 SNPs, 30 indels, and 267 structural variants (including 1478 duplicates) that were specifically selected to enhance the genomic resolution for diverse goat breeds. In this talk, we report the design and development process of the updated SNP chip, including the selection of around 22 thousand new variants, which improve coverage across key genomic regions. Markers associated with important traits such as resistance to paratuberculosis, and variation in the casein gene region have been included. Furthermore, markers predicted to have a high impact on protein function and those frequently identified in genotyping-by-sequencing datasets were also incorporated. The validation of the chip was conducted using 384 goats representing over 20 breeds, resulting in successful clustering of 79,538 variants. This updated SNP chip is expected to facilitate the discovery of the genetic basis of traits of economic interest in goats, paving the way for improved breeding programs and better management of goat populations. The advancements made in this update hold the potential to significantly impact goat production and research, ultimately contributing to genetic improvement and sustainability in the livestock sector.
Domaines
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