A. Asimakopoulos, N. Thomaidis, and K. Kannan, Widespread occurrence of bisphenol A diglycidyl ethers, p-hydroxybenzoic acid esters (parabens), benzophenone type-UV filters, triclosan, and triclocarban in human urine from Athens, Greece, Science of The Total Environment, vol.470, issue.471, pp.470-4711243, 2014.
DOI : 10.1016/j.scitotenv.2013.10.089

D. Badger, R. Smith, J. Bao, R. Kuester, and I. Sipes, Disposition and metabolism of isoeugenol in the male Fischer 344 rat, Food and Chemical Toxicology, vol.40, issue.12, pp.1757-1765, 2002.
DOI : 10.1016/S0278-6915(02)00183-7

S. Boase and J. Miners, In vitro-in vivo correlations for drugs eliminated by glucuronidation: Investigations with the model substrate zidovudine, British Journal of Clinical Pharmacology, vol.47, issue.Suppl 2A, pp.493-503, 2002.
DOI : 10.1046/j.1365-2125.1999.00935.x

H. Brown, A. Chadwick, and J. Houston, Use of Isolated Hepatocyte Preparations for Cytochrome P450 Inhibition Studies: Comparison with Microsomes for Ki Determination, Drug Metabolism and Disposition, vol.35, issue.11, pp.2119-2126, 2007.
DOI : 10.1124/dmd.107.017095

B. Louis, G. Chen, Z. Kim, S. Sapra, K. Bae et al., Urinary concentrations of benzophenone-type ultraviolet light filters and semen quality, Fertility and sterility, vol.104, issue.4, 2014.

J. Burkey, J. Sauer, C. Mcqueen, and I. Sipes, Cytotoxicity and genotoxicity of methyleugenol and related congeners ??? a mechanism of activation for methyleugenol, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol.453, issue.1, pp.25-33, 2000.
DOI : 10.1016/S0027-5107(00)00070-1

G. De-sousa, S. Langouet, F. Nicolas, G. Lorenzon, M. Placidi et al., Increase of cytochrome P-450 1A and glutathione transferase transcripts in cultured hepatocytes from dogs, monkeys, and humans after cryopreservation, Cell Biology and Toxicology, vol.25, issue.6, pp.351-358, 1996.
DOI : 10.1007/BF00438170

G. De-sousa, F. Fontaine, M. Pralavorio, D. Botta-fridlund, Y. Letreut et al., Insecticide cytotoxicity and CYP1A1/2 induction in primary human and rat hepatocyte cultures, Toxicology in Vitro, vol.11, issue.5, pp.451-457125, 1997.
DOI : 10.1016/S0887-2333(97)00061-1

K. Ito and J. Houston, Comparison of the Use of Liver Models for Predicting Drug Clearance Using in Vitro Kinetic Data from Hepatic Microsomes and Isolated Hepatocytes, Pharmaceutical Research, vol.21, issue.5, pp.785-792, 2004.
DOI : 10.1023/B:PHAM.0000026429.12114.7d

M. Jacobs, W. Janssens, U. Bernauer, E. Brandon, S. Coecke et al., The Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors, Current Drug Metabolism, vol.9, issue.8, pp.796-826, 2008.
DOI : 10.2174/138920008786049294

N. Janjua, B. Mogensen, A. Andersson, J. Petersen, M. Henriksen et al., Systemic Absorption of the Sunscreens Benzophenone-3, Octyl-Methoxycinnamate, and 3-(4-Methyl-Benzylidene) Camphor After Whole-Body Topical Application and Reproductive Hormone Levels in Humans, Journal of Investigative Dermatology, vol.123, issue.1, pp.57-61, 2004.
DOI : 10.1111/j.0022-202X.2004.22725.x

H. Jeon, S. Sarma, Y. Kim, and J. Ryu, Toxicokinetics and metabolisms of benzophenone-type UV filters in rats, Toxicology, vol.248, issue.2-3, pp.89-95, 2008.
DOI : 10.1016/j.tox.2008.02.009

H. Jones and J. Houston, SUBSTRATE DEPLETION APPROACH FOR DETERMINING IN VITRO METABOLIC CLEARANCE: TIME DEPENDENCIES IN HEPATOCYTE AND MICROSOMAL INCUBATIONS, Drug Metabolism and Disposition, vol.32, issue.9, pp.973-982, 2004.
DOI : 10.1124/dmd.104.000125

G. Kerdivel, L. Guevel, R. Habauzit, D. Brion, F. Ait-aissa et al., Estrogenic Potency of Benzophenone UV Filters in Breast Cancer Cells: Proliferative and Transcriptional Activity Substantiated by Docking Analysis, PLoS ONE, vol.81, issue.1, p.60567, 2013.
DOI : 10.1371/journal.pone.0060567.t002

URL : https://hal.archives-ouvertes.fr/inserm-00838323

Y. Kim, J. Ryu, H. Choi, and K. Lee, Effect of 2,2???,4,4???-tetrahydroxybenzophenone (BP2) on steroidogenesis in testicular Leydig cells, Toxicology, vol.288, issue.1-3, pp.18-26, 2011.
DOI : 10.1016/j.tox.2011.06.013

A. Kortenkamp, M. Scholze, and S. Ermler, Mind the gap: can we explain declining male reproductive health with known antiandrogens?, REPRODUCTION, vol.157, issue.2, pp.515-527, 2014.
DOI : 10.1006/taap.1999.8673

URL : http://www.reproduction-online.org/content/147/4/515.full.pdf

R. Kuester and I. Sipes, Prediction of Metabolic Clearance of Bisphenol A (4,4 '-Dihydroxy-2,2-diphenylpropane) using Cryopreserved Human Hepatocytes, Drug Metabolism and Disposition, vol.35, issue.10, pp.1910-1915, 2007.
DOI : 10.1124/dmd.107.014787

P. Kunz, K. Fent, A. Gruters, W. Wuttke, H. Jarry et al., Estrogenic activity of UV filter mixtures, Toxicology and Applied Pharmacology, vol.217, issue.1, pp.86-2835, 2006.
DOI : 10.1016/j.taap.2006.07.014

D. Seidlova-wuttke, H. Jarry, and W. Wuttke, Pure estrogenic effect of benzophenone-2 (BP2) but not of bisphenol A (BPA) and dibutylphtalate (DBP) in uterus, vagina and bone, Toxicology, vol.205, issue.1-2, pp.103-112, 2004.
DOI : 10.1016/j.tox.2004.06.042

E. Silva, N. Rajapakse, M. Scholze, T. Backhaus, S. Ermler et al., Joint Effects of Heterogeneous Estrogenic Chemicals in the E-Screen???Exploring the Applicability of Concentration Addition, Toxicological Sciences, vol.45, issue.2, pp.383-394, 2011.
DOI : 10.1016/j.fct.2007.06.011

M. Soars, B. Burchell, and R. Riley, In Vitro Analysis of Human Drug Glucuronidation and Prediction of in Vivo Metabolic Clearance, Journal of Pharmacology and Experimental Therapeutics, vol.301, issue.1, pp.382-390, 2002.
DOI : 10.1124/jpet.301.1.382

C. Strassburg, Pharmacogenetics of Gilbert???s syndrome, Pharmacogenomics, vol.44, issue.6, pp.703-715, 2008.
DOI : 10.1046/j.1442-200X.2002.01577.x

T. Lusin, T. Roskar, R. Mrhar, and A. , Evaluation of bisphenol A glucuronidation according to UGT1A1*28 polymorphism by a new LC???MS/MS assay, Toxicology, vol.292, issue.1, pp.33-41, 2012.
DOI : 10.1016/j.tox.2011.11.015

F. Vondran, E. Katenz, R. Schwartlander, M. Morgul, N. Raschzok et al., Isolation of Primary Human Hepatocytes After Partial Hepatectomy: Criteria for Identification of the Most Promising Liver Specimen, Artificial Organs, vol.130, issue.1, pp.205-213, 2008.
DOI : 10.1016/j.jhep.2006.02.015

Y. Watanabe, M. Nakajima, N. Ohashi, T. Kume, and T. Yokoi, Glucuronidation of Etoposide in Human Liver Microsomes Is Specifically Catalyzed by UDP-Glucuronosyltransferase 1A1, Drug Metabolism and Disposition, vol.31, issue.5, pp.589-595, 2003.
DOI : 10.1124/dmd.31.5.589

URL : http://dmd.aspetjournals.org/content/dmd/31/5/589.full.pdf

C. Weisbrod, P. Kunz, A. Zenker, and K. Fent, Effects of the UV filter benzophenone-2 on reproduction in fish, Toxicology and Applied Pharmacology, vol.225, issue.3, pp.255-266, 2007.
DOI : 10.1016/j.taap.2007.08.004

J. Williams, B. Ring, V. Cantrell, K. Campanale, D. Jones et al., Differential Modulation of UDP-Glucuronosyltransferase 1A1 (UGT1A1)-Catalyzed Estradiol-3-glucuronidation by the Addition of UGT1A1 Substrates and Other Compounds to Human Liver Microsomes, Drug Metabolism and Disposition, vol.30, issue.11, pp.1266-1273, 2002.
DOI : 10.1124/dmd.30.11.1266