The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis, Arthritis & Rheumatism, vol.4, issue.11, pp.1205-1213, 1987. ,
DOI : 10.1002/art.1780301102
Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis, Am J Hum Genet, vol.58, pp.371-383, 1996. ,
Modelling the major histocompatibility complex susceptibility to RA using the MASC method, Genetic Epidemiology, vol.86, issue.4, pp.419-430, 1998. ,
DOI : 10.1002/(SICI)1098-2272(1998)15:4<419::AID-GEPI7>3.0.CO;2-X
HLA haplotype sharing in rheumatoid arthritis sibships: Risk estimates subdivided by proband genotype, Genetic Epidemiology, vol.33, issue.4, pp.403-418, 1998. ,
DOI : 10.1002/(SICI)1098-2272(1998)15:4<403::AID-GEPI6>3.0.CO;2-2
Modeling the HLA component in rheumatoid arthritis: Sensitivity to DRB1 allele frequencies, Genetic Epidemiology, vol.51, issue.4, pp.422-428, 2000. ,
DOI : 10.1002/1098-2272(200012)19:4<422::AID-GEPI12>3.0.CO;2-A
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility, Arthritis & Rheumatism, vol.168, issue.4, pp.1063-1068, 2005. ,
DOI : 10.1002/art.20989
A new method to test genetic models in HLA associated diseases: the MASC method, Annals of Human Genetics, vol.21, issue.3, pp.247-258, 1988. ,
DOI : 10.1016/0010-4809(84)90013-2
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis, Arthritis & Rheumatism, vol.143, issue.3, pp.315-324, 1988. ,
DOI : 10.1002/art.1780310302
On Estimating HLA/Disease Association with Application to a Study of Aplastic Anemia, Biometrics, vol.47, issue.1, pp.53-61, 1991. ,
DOI : 10.2307/2532495
A Unified Stepwise Regression Procedure for Evaluating the Relative Effects of Polymorphisms within a Gene Using Case/Control or Family Data: Application to HLA in Type 1 Diabetes, The American Journal of Human Genetics, vol.70, issue.1, pp.124-141, 2002. ,
DOI : 10.1086/338007
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis, Arthritis & Rheumatism, vol.5, issue.10, pp.3085-3092, 2004. ,
DOI : 10.1002/art.20553
A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA???DR (shared epitope)???restricted immune reactions to autoantigens modified by citrullination, Arthritis & Rheumatism, vol.16, issue.1, pp.38-46, 2006. ,
DOI : 10.1002/art.21575
A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis, The American Journal of Human Genetics, vol.75, issue.2, pp.330-337, 2004. ,
DOI : 10.1086/422827
Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22?620 W allele, Arthritis Research & Therapy, vol.7, issue.6, pp.1200-1207, 2005. ,
DOI : 10.1186/ar1812
Dissecting the Genetic Complexity of the Association between Human Leukocyte Antigens and Rheumatoid Arthritis, The American Journal of Human Genetics, vol.71, issue.3, pp.585-594, 2002. ,
DOI : 10.1086/342407
A review of the MHC genetics of rheumatoid arthritis, Genes and Immunity, vol.5, issue.3, pp.151-157, 2004. ,
DOI : 10.1038/sj.gene.6364045
An independent role of protective HLA class II alleles in rheumatoid arthritis severity and susceptibility, Arthritis & Rheumatism, vol.2, issue.9, pp.2637-2644, 2005. ,
DOI : 10.1002/art.21272
HLA-DRB1 alleles encoding an aspartic acid at position 70 protect against development of rheumatoid arthritis, J Rheumatol, vol.28, pp.232-239, 2001. ,
Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule, Arthritis & Rheumatism, vol.32, issue.4, pp.921-928, 2002. ,
DOI : 10.1002/art.10210
Hla-dr alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis, Arthritis & Rheumatism, vol.240, issue.7, pp.939-941, 1990. ,
DOI : 10.1002/art.1780330704
The shared epitope and severity of rheumatoid arthritis, Rheumatic Disease Clinics of North America, vol.28, issue.1, pp.59-78, 2002. ,
DOI : 10.1016/S0889-857X(03)00069-3
A new classification of HLA???DRB1 alleles differentiates predisposing and protective alleles for rheumatoid arthritis structural severity, Arthritis & Rheumatism, vol.64, issue.2, pp.593-599, 2006. ,
DOI : 10.1002/art.21630