An introduction to the molecular basics of aryl 318 hydrocarbon receptor biology, Biological chemistry, vol.391, pp.1235-1283, 2010. ,
The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein, FEBS Letters, vol.21, issue.182, pp.3608-3623, 2007. ,
DOI : 10.1016/j.febslet.2007.03.046
[Role of tumor necrosis factor in the male gonad]. Contraception, 322 fertilite, sexualite, pp.569-71, 1992. ,
Paracrine effect of seminiferous tubule 324 factors on rat Leydig cell testosterone production: role of cytoskeleton, under the auspices of the European Cell Biology Organization, pp.435-477, 1997. ,
Dioxin-dependent 327 and dioxin-independent gene batteries: comparison of liver and kidney in AHR-null mice, Toxicol Sci, vol.112, pp.328-245, 2009. ,
334 MAPK phosphatase-1 (MKP-1) expression is up-regulated by hCG/cAMP and modulates 335 steroidogenesis in MA-10 Leydig cells, Endocrinology, vol.152, pp.2665-77, 2011. ,
Cytochrome P450 CYP1B1 338 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas, 339 Proceedings of the National Academy of Sciences of the United States of America 96, pp.1977-340, 1999. ,
Stimulation of Adult Rat Leydig Cell Aromatase Activity by a Sertoli Cell Factor*, Endocrinology, vol.122, issue.3, pp.1103-1112, 1988. ,
DOI : 10.1210/endo-122-3-1103
Cellular defense mechanisms 345 against benzo[a]pyrene in testicular Leydig cells: implications of p53, aryl-hydrocarbon 346 receptor, and cytochrome P450 1A1 status, Endocrinology, vol.148, pp.6134-6178, 2007. ,
Protective effect of curcumin on immune system and body weight gain on rats intoxicated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), Immunopharmacology and Immunotoxicology, vol.73, issue.1, pp.99-104, 2010. ,
DOI : 10.1016/0041-008X(84)90357-0
Regulation of Cytochrome P450 1B1 Expression by 351 Luteinizing Hormone in Mouse MA-10 and Rat R2C Leydig Cells: Role of Protein Kinase A. 352 Biology of reproduction, p.353, 2011. ,
CYP1B1 expression in rat 354 testis and Leydig cells is not inducible by aryl hydrocarbon receptor agonists. Xenobiotica; 355 the fate of foreign compounds in biological systems, pp.447-57, 2010. ,
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement, Endocrine Reviews, vol.30, issue.4, pp.293-342, 2009. ,
DOI : 10.1210/er.2009-0002
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726844
Gene Expression in Rat Leydig Cells During Development from the Progenitor to Adult Stage: A Cluster Analysis1, Biology of Reproduction, vol.72, issue.6, pp.1405-1420, 2005. ,
DOI : 10.1095/biolreprod.104.037499
Chemokines, a Family of Chemotactic Cytokines, Critical Reviews in Oral Biology & Medicine, vol.6, issue.2, pp.109-127, 1995. ,
DOI : 10.1177/10454411950060020101
Cytokines and chemokines 365 in testicular inflammation: A brief review, Microscopy research and technique 72, pp.620-628, 2009. ,
Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways, Biochemical Pharmacology, vol.77, issue.4, pp.508-528, 0368. ,
DOI : 10.1016/j.bcp.2008.09.013
Molecular mechanism of suppression of testicular steroidogenesis by 371 proinflammatory cytokine tumor necrosis factor alpha, Molecular and cellular biology, vol.370, issue.372, pp.2593-604, 2004. ,
Fifteen years after "Wingspread"-- 375 environmental endocrine disrupters and human and wildlife health: where we are today and 376 where we need to go, Toxicol Sci, vol.105, pp.235-59, 2008. ,
A proposed mechanism for the protective effect of dioxin against 379 breast cancer, Toxicol Sci, vol.98, pp.436-480, 2007. ,
Human chorionic gonadotrophin attenuates NF-??B activation and cytokine expression of endometriotic stromal cells, Molecular Human Reproduction, vol.13, issue.8, pp.595-604, 2007. ,
DOI : 10.1093/molehr/gam032
-Tetrachlorodibenzo-p-dioxin reduces the number, size, and organelle content of 385 Leydig cells in adult rat testes, Toxicology, vol.38437, issue.89, pp.49-65, 1994. ,
URL : https://hal.archives-ouvertes.fr/jpa-00210025
Inhibition of testicular 387 steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats: evidence that the key 388 lesion occurs prior to or during pregnenolone formation, pp.112-137, 1990. ,
Primary structure and inducibility 391 by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a 392 TCDD-sensitive and a TCDD-resistant rat strain, Biochemical and biophysical research 393 communications 315, pp.123-154, 2004. ,
Inhibition of CYP450scc expression in dioxin-exposed rat Leydig cells, Journal of Endocrinology, vol.185, issue.3, pp.519-546, 2005. ,
DOI : 10.1677/joe.1.06054
397 Developmental expression and endocrine regulation of CYP1B1 in rat testis. Drug 398 metabolism and disposition: the biological fate of chemicals, pp.523-531, 2009. ,
The effects of PCBs and dioxins on child 401 health, Acta Paediatr, pp.55-64, 2006. ,
anthracene inhibition of steroid production in MA-10 mouse Leydig tumor 404 cells is not directly linked to induction of CYP1B1, Toxicology and applied pharmacology, vol.405, pp.175-200 ,
A comprehensive survey of the laminins and collagens type IV expressed in mouse 408, 2008. ,
Leydig cell aging and the mechanisms of reduced testosterone synthesis, Molecular and Cellular Endocrinology, vol.299, issue.1, pp.23-31, 2009. ,
DOI : 10.1016/j.mce.2008.07.016
Identification of a novel mechanism of regulation of Ah (dioxin) receptor function, Genes & Development, vol.13, issue.1, pp.20-25, 1999. ,
DOI : 10.1101/gad.13.1.20
Functional role of AhR in the expression of toxic effects by TCDD, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1619, issue.3, pp.263-271, 2003. ,
DOI : 10.1016/S0304-4165(02)00485-3
8-tetrachlorodibenzo-p-dioxin. 419 Toxicology and applied pharmacology 79, Androgenic deficiency in male rats treated with 2, pp.99-111 ,
Aryl hydrocarbon receptor- 422 and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant 423 benzo, pp.19906-19921, 2006. ,
2,3,7,8-Tetrachlorodibenzo-p-Dioxin Impairs an Insulin Signaling Pathway through the Induction of Tumor Necrosis Factor-?? in Adipocytes, Toxicological Sciences, vol.115, issue.2, pp.482-91, 2008. ,
DOI : 10.1093/toxsci/kfq052
The evolution of mammalian chemokine genes, Cytokine & Growth Factor Reviews, vol.21, issue.4, pp.253-62, 2010. ,
DOI : 10.1016/j.cytogfr.2010.03.004
The effects of an in utero 431 exposure to 2,3,7,8-tetrachloro-dibenzo-p-dioxin on male reproductive function: identification 432 of Ccl5 as a potential marker, International journal of andrology, vol.33, pp.413-437, 2010. ,
Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor 435 nuclear translocator messenger ribonucleic acids and proteins in rat and human testis, 436 Endocrinology, vol.144, pp.767-76, 2003. ,
Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and1B1, Cancer Science, vol.12, issue.1, pp.1-6, 2004. ,
DOI : 10.1126/science.275.5297.218
Testicular dysgenesis 440 syndrome: an increasingly common developmental disorder with environmental aspects, Human reproduction, vol.441, issue.16, pp.972-980, 2001. ,
DOI : 10.1111/j.1600-0463.2001.tb05770.x
Male reproductive health and environmental xenoestrogens, Environmental health 446 perspectives 104, pp.741-803, 1996. ,
448 Modulation of the chemokines KC and MCP-1 by 2, TCDD) in mice. Archives of biochemistry and biophysics 461, pp.8-449, 2007. ,
Combination of 451 estrogen and dioxin is involved in the pathogenesis of endometriosis by promoting chemokine 452 secretion and invasion of endometrial stromal cells, Human reproduction, vol.23, pp.453-1614, 2008. ,
Dioxin 455 stimulates RANTES expression in an in-vitro model of endometriosis, Molecular human 456 reproduction, pp.849-54, 2002. ,