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Platelet lipids were extracted and separated by TLC, and metabolites of [ 14 C] ARA were quantified by radio-chromatography. Basal formations of TxB 2 in unstimulated platelets (in grey) and of one major urinary metabolites of TxB 2 , 11- dehydro-TxB 2, were quantified by immunoassays. Plasma, platelet vitamin E (alphatocopherol) and platelet MDA were extracted and quantified after HPLC separation. Urinary isoprostanes were quantified by immunoassays. There were no significant differences between pre placebo and post placebo values. All values are means ± SEM ,