Vitamin A deficiency disorders: international efforts to control a preventable "pox, J Nutr, vol.134, pp.231-237, 2004. ,
Vitamin deficiencies in humans: can plant science help, Plant Cell, vol.24, pp.395-414, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478611
Golden Rice is an effective source of vitamin A, Am J Clin Nutr, vol.89, pp.1776-83, 2009. ,
Golden Rice: introducing the beta-carotene biosynthesis pathway into rice endosperm by genetic engineering to defeat vitamin A deficiency, J Nutr, vol.132, pp.506-516, 2002. ,
Vitamin A policies need rethinking, Int J Epidemiol, vol.44, pp.283-92, 2015. ,
Commentary: vitamin A policies need rethinking, Int J Epidemiol, vol.44, pp.292-296, 2015. ,
Premature abandonment of global vitamin A supplementation programmes is not prudent!, Int J Epidemiol, vol.44, pp.297-306, 2015. ,
Factors affecting intestinal absorption of highly lipophilic food microconstituents (fat-soluble vitamins, carotenoids and phytosterols) ,
, Clin Chem Lab Med, vol.41, pp.979-94, 2003.
Quantification of the ''SLAMENGHI'' factors for carotenoid bioavailability and bioconversion, Int J Vitam Nutr Res, vol.68, pp.371-378, 1998. ,
Dietary carotenoids and their role in combating vitamin A deficiency: a review of the litterature, Eur J Clin Nutr, vol.50, pp.38-53, 1996. ,
Provitamin A food sources and serum retinol, Am J Clin Nutr, vol.70, p.575, 1999. ,
Provitamin A food sources and serum retinol -Reply to EH Harrison and JC Smith, Am J Clin Nutr, vol.70, pp.575-581, 1999. ,
Azais-Braesco V. Low and high responders to pharmacological doses of beta-carotene: proportion in the population, mechanisms involved and consequences on beta-carotene metabolism, J Lipid Res, vol.39, pp.2250-60, 1998. ,
Single nucleotide polymorphisms upstream from the beta-carotene 15,15'-monoxygenase gene influence provitamin a conversion efficiency in female volunteers, J Nutr, vol.142, pp.161-166, 2012. ,
Two common single nucleotide polymorphisms in the gene encoding beta-carotene 15,15'-monoxygenase alter beta-carotene metabolism in female volunteers, FASEB J, vol.23, pp.1041-53, 2009. ,
The human enzyme that converts dietary provitamin A carotenoids to vitamin A is a dioxygenase, J Biol Chem, vol.289, pp.13661-13667, 2014. ,
Substrate specificity of purified recombinant human beta-carotene 15,15'-oxygenase (BCO1), J Biol Chem, vol.288, pp.37094-103, 2013. ,
Two carotenoid oxygenases contribute to mammalian provitamin A metabolism, J Biol Chem, vol.288, pp.34081-96, 2013. ,
Provitamin A metabolism and functions in mammalian biology, Am J Clin Nutr, vol.96, pp.1234-1278, 2012. ,
Mammalian carotenoid-oxygenases: key players for carotenoid function and homeostasis, Biochim Biophys Acta, vol.1821, pp.78-87, 2012. ,
Mammalian metabolism of beta-carotene: gaps in knowledge, Nutrients, vol.5, pp.4849-68, 2013. ,
Alpha-and beta-carotene from a commercial puree are more bioavailable to humans than from boiled-mashed carrots, as determined using an extrinsic stable isotope reference method, J Nutr, vol.132, pp.159-67, 2002. ,
A minute dose of 14c-{beta}-carotene is absorbed and converted to retinoids in humans, J Nutr, vol.139, pp.1480-1486, 2009. ,
Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men, Am J Clin Nutr, vol.68, pp.82-91, 1998. ,
Avocado consumption enhances human postprandial provitamin A absorption and conversion from a novel high-beta-carotene tomato sauce and from carrots, J Nutr, vol.144, pp.1158-66, 2014. ,
Genetic variations involved in interindividual variability in carotenoid status, Mol Nutr Food Res, vol.56, pp.228-268, 2012. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478620
Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: A genome-wide association study, Am J Hum Genet, vol.84, pp.123-156, 2009. ,
Interindividual variability of lutein bioavailability in healthy men: characterization, genetic variants involved, and relation with fasting plasma lutein concentration, Am J Clin Nutr, vol.100, pp.168-75, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478524
Can genetic variability in alpha-tocopherol bioavailability explain the heterogeneous response to alpha-tocopherol supplements?, Antioxid Redox Signal, vol.22, pp.669-78, 2015. ,
Collection of blood, saliva, and buccal cell samples in a pilot study on the Danish nurse cohort: comparison of the response rate and quality of genomic DNA, Cancer Epidemiol Biomarkers Prev, vol.16, pp.2072-2078, 2007. ,
Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans, Am J Clin Nutr, vol.93, pp.644-51, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478659
Azais-Braesco V. Chylomicron beta-carotene and retinyl palmitate responses are dramatically diminished when men ingest beta-carotene with medium-chain rather than long-chain triglycerides, J Nutr, vol.128, pp.1361-1368, 1998. ,
Lycopene bioavailability is associated with a combination of genetic variants, Free Radic Biol Med, vol.83, pp.238-282, 2015. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478367
The postprandial chylomicron triacylglycerol response to dietary fat in healthy male adults is significantly explained by a combination of single nucleotide polymorphisms in genes involved in triacylglycerol metabolism, J Clin Endocrinol Metab, vol.99, pp.484-492, 2014. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478528
Quantitative determination of serum triglycerides by the use of enzymes, Clin Chem, vol.19, pp.476-82, 1973. ,
Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficiency, Clin Chem, vol.29, pp.1075-80, 1983. ,
Immobilized enzymes in continuous-flow analysis, Advances in automated analysis Technicon International Congress, vol.1, pp.86-95, 1976. ,
Review of a technic for the estimation of area under the concentration curve in pharmacokinetic analysis, Therapie, vol.48, pp.1-5, 1993. ,
CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans, J Nutr, vol.143, pp.448-56, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478566
Mechanisms involved in the intestinal absorption of dietary vitamin A and provitamin A carotenoids, Biochim Biophys Acta, vol.1821, pp.70-77, 2012. ,
Class B scavenger receptor-mediated intestinal absorption of dietary betacarotene and cholesterol, Biochemistry, vol.44, pp.4517-4542, 2005. ,
Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe, J Nutr, vol.135, pp.2305-2317, 2005. ,
Proteins involved in uptake, intracellular transport and basolateral secretion of fat-soluble vitamins and carotenoids by mammalian enterocytes, Prog Lipid Res, vol.50, pp.388-402, 2011. ,
URL : https://hal.archives-ouvertes.fr/inserm-01478631
ISX is a retinoic acid-sensitive gatekeeper that controls intestinal beta,beta-carotene absorption and vitamin A production, FASEB J, vol.24, pp.1656-66, 2010. ,
Genome-wide association study of circulating retinol levels, Hum Mol Genet, vol.20, pp.4724-4755, 2011. ,
beta-Carotene 15,15'-monooxygenase 1 single nucleotide polymorphisms in relation to plasma carotenoid and retinol concentrations in women of European descent, Am J Clin Nutr, vol.96, pp.1379-89, 2012. ,
Human plasma levels of vitamin E and carotenoids are associated with genetic polymorphisms in genes involved in lipid metabolism, J Nutr, vol.137, pp.2653-2662, 2007. ,
URL : https://hal.archives-ouvertes.fr/inserm-00192323
Addressing the identification problem in age-period-cohort analysis: a tutorial on the use of partial least squares and principal components analysis, Epidemiology, vol.23, pp.583-93, 2012. ,
Assessing the impact of body size in childhood and adolescence on blood pressure: an application of partial least squares regression, Epidemiology, vol.21, pp.440-448, 2010. ,
1H NMR metabonomics can differentiate the early atherogenic effect of dairy products in hyperlipidemic hamsters, Atherosclerosis, vol.206, pp.127-160, 2009. ,
URL : https://hal.archives-ouvertes.fr/inserm-00370368
Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fatfed mice, J Lipid Res, vol.52, pp.1373-82, 2011. ,
A direct approach to false discovery rates, J R Stat Soc Series B Stat Methodol, vol.64, pp.479-98, 2002. ,
, The International Hapmap Project, 2014.
, Database of Single Nucleotide Polymorphisms (dbSNP), vol.54
, , 2014.
beta-Carotene intestinal absorption: bile, fatty acid, pH, and flow rate effects on transport, Am J Physiol, vol.235, pp.686-91, 1978. ,
Molecular mechanisms of vitamin E transport, Annu Rev Nutr, vol.19, pp.343-55, 1999. ,
Absorption, lipoprotein transport, and regulation of plasma concentrations of vitamin E in humans, J Lipid Res, vol.34, pp.343-58, 1993. ,
Rat intestinal beta-carotene dioxygenase activity is located primarily in the cytosol of mature jejunal enterocytes, J Nutr, vol.126, pp.2550-2556, 1996. ,
Azais-Braesco V. In vitro and in vivo inhibition of beta-carotene dioxygenase activity by canthaxanthin in rat intestine, Arch Biochem Biophys, vol.348, pp.233-241, 1997. ,
Vitamin A formation in animals: molecular identification and functional characterization of carotene cleaving enzymes, J Nutr, vol.134, pp.251-257, 2004. ,
Molecular and dietary regulation of beta, beta-carotene 15,15'-monooxygenase 1 (BCMO1), Arch Biochem Biophys, vol.502, pp.8-16, 2010. ,
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters, Science, vol.290, pp.1771-1776, 2000. ,
Carotenoids, inflammation, and oxidative stressimplications of cellular signaling pathways and relation to chronic disease prevention, Nutr Res, vol.34, pp.907-936, 2014. ,
beta-Carotene and lutein inhibit hydrogen peroxide-induced activation of NF-kappaB and IL-8 expression in gastric epithelial AGS cells, J Nutr Sci Vitaminol (Tokyo), vol.57, pp.216-239, 2011. ,
Carotenoids are more bioavailable from papaya than from tomato and carrot in humans: A randomised cross-over study, Br J Nutr, vol.111, pp.490-498, 2014. ,
Vegetable-borne lutein, lycopene, and beta-carotene compete for incorporation into chylomicrons, with no adverse effect on the medium-term (3-wk) plasma status of carotenoids in humans, Am J Clin Nutr, vol.75, pp.526-560, 2002. ,
, SNPs associated with b-carotene bioavailability 1747