B. Dubos, Maladies cryptogamiques de la vigne -Les champignons parasites des organes herbacés et du bois de la vigne, 2002.

C. Gessler, I. Pertot, and M. Perazzolli, Plasmopara viticola: a review of knowledge on downy mildew of grapevine and effective disease management, Phytopathologia Mediterranea, vol.50, pp.3-44, 2011.

M. Jermini, P. Blaise, and C. Gessler, Quantitative effect of leaf damage caused by downy mildew (Plasmopara viticola) on growth and yield quality of grapevine 'Merlot' (Vitis vinifera), VITIS -Journal of Grapevine Research, vol.49, pp.77-85, 2010.

, The use of plant protection products in the European Union, data, 1992.

, Service de la Statistique et de la Prospection, Enquête Pratique culturales en viticulture 2013 -Nombre de traitements phytosanitaires, 2015.

T. Caffi, V. Rossi, and R. Bugiani, Evaluation of a warning system for controlling primary infections of grapevine downy mildew, Plant disease, vol.94, pp.709-716, 2010.

J. F. Viel and B. Challier, Bladder cancer among French farmers: does exposure to pesticides in vineyards play a part?, Occupational and Environmental Medicine, vol.52, pp.587-592, 1995.

I. Baldi, Neuropsychologic effects of long-term exposure to pesticides: results from the French Phytoner study, Environmental Health Perspectives, vol.109, pp.839-844, 2001.

I. Baldi, Association between Parkinson's disease and exposure to pesticides in southwestern France, Neuroepidemiology, vol.22, pp.305-310, 2003.

I. Baldi, Neurodegenerative diseases and exposure to pesticides in the elderly, American Journal of Epidemiology, vol.157, pp.409-414, 2003.

D. Provost, Brain tumours and exposure to pesticides: a case-control study in southwestern France, Occupational and Environmental Medicine, vol.64, pp.509-514, 2007.

, Guidance on the assessment of exposure of operators, workers, residents and bystanders in risk assessment for plant protection products: Guidance on pesticides exposure assessment of operators, workers, residents and bystanders, EFSA Journal, vol.12, p.3874, 2014.

A. , Agence nationale de sécurité sanitaire de l'alimentation, de l' environnement et du travail relatif à l' efficacité de vêtements de protection portés par les applicateurs de produits phytopharmaceutiques -Saisine, 2014.

A. Garrigou, I. Baldi, and M. Jackson, The use of pesticides in French viticulture: a badly controlled technology transfert, 2012.

S. Grimbuhler and J. Viel, Physiological strain in French vineyard workers wearing protective equipment to conduct re-entry tasks in humid conditions, Annals of Work Exposures and Health, vol.62, pp.1040-1046, 2018.
URL : https://hal.archives-ouvertes.fr/hal-01863792

A. Seidler, Cancer risk among residents of Rhineland-Palatinate winegrowing communities: a cancer-registry based ecological study, Journal of Occupational Medicine and Toxicology, vol.3, p.12, 2008.

S. Kab, Agricultural activities and the incidence of Parkinson's disease in the general French population, European Journal of Epidemiology, vol.32, pp.203-216, 2017.

, /128/CE du Parlement européen et du Conseil du 21 octobre 2009 instaurant un cadre d'action communautaire pour parvenir à une utilisation des pesticides compatible avec le développement durable (Texte présentant de l'intérêt pour l'EEE), vol.309, 2009.

, Ministère de l' Agriculture, de l' Agroalimentaire et de la Forêt, Plan ECOPHYTO II+, 2018.

, Scientific RepoRtS |, vol.10, p.6404, 2020.

F. Mailly, L. Hossard, J. Barbier, M. Thiollet-scholtus, and C. Gary, Quantifying the impact of crop protection practices on pesticide use in wine-growing systems, European Journal of Agronomy, vol.84, pp.23-34, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01604395

P. Menesatti, Multivariate forecasting model to optimize management of grape downy mildew control, VITIS -Journal of Grapevine Research, vol.52, pp.141-148, 2015.

M. Chen, F. Brun, M. Raynal, and D. Makowski, Timing of grape downy mildew onset in Bordeaux vineyards, Phytopathology, vol.109, pp.787-795, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02310092

C. Großkopf, A new model for the prediction of agricultural operator exposure during professional application of plant protection products in outdoor crops, Journal für Verbraucherschutz und Lebensmittelsicherheit, vol.8, pp.143-153, 2013.

, Pratiques culturales en viticulture 2013 -Réduire la dose, une pratique répandue pour les traitements fongicides, vol.8, 2016.

, Fortes disparités de protection contre l'oïdium et le mildiou, vol.8, 2012.

, Tableau fongicides, 2019.

J. Ross, J. Driver, C. Lunchick, and C. O'mahony, Models for estimating human exposure to pesticides, Outlooks on Pest Management, vol.26, pp.33-37, 2015.

I. Thouvenin, F. Bouneb, and T. Mercier, Operator dermal exposure and protection provided by personal protective equipment and working coveralls during mixing/loading, application and sprayer cleaning in vineyards, International Journal of Occupational Safety and Ergonomics, vol.23, pp.229-239, 2017.

I. Baldi, Levels and determinants of pesticide exposure in operators involved in treatment of vineyards: results of the PESTEXPO Study, Journal of Exposure Science & Environmental Epidemiology, vol.22, pp.593-600, 2012.

J. P. Grillet, Arsenic exposure in the wine growing industry in ten French departments, Int Arch Occup Environ Health, vol.77, pp.130-135, 2004.

I. Baldi, Pesticide contamination of workers in vineyards in France, J Expo Sci Environ Epidemiol, vol.16, pp.115-124, 2006.

S. Kab, F. Moisan, J. Spinosi, L. Chaperon, and A. Elbaz, Incidence de la maladie de Parkinson chez les agriculteurs et en population générale en fonction des caractéristiques agricoles des cantons français, Bulletin épidémiologique hebdomadaire, pp.157-167, 2018.

I. Baldi, Neurobehavioral effects of long-term exposure to pesticides: results from the 4-year follow-up of the PHYTONER Study, Occupational and Environmental Medicine, vol.68, pp.108-115, 2011.

C. A. Damalas and G. Abdollahzadeh, Farmers' use of personal protective equipment during handling of plant protection products: Determinants of implementation, Science of The Total Environment, vol.571, pp.730-736, 2016.

P. Lebailly, Exposure to pesticides in open-field farming in France, Ann Occup Hyg, vol.53, pp.69-81, 2009.

C. A. Damalas and I. G. Eleftherohorinos, Pesticide exposure, safety issues, and risk assessment indicators, International Journal of Environmental Research and Public Health, vol.8, pp.1402-1419, 2011.

L. Delière, P. Cartolaro, B. Léger, and O. Naud, Field evaluation of an expertise-based formal decision system for fungicide management of grapevine downy and powdery mildews: Decision system for management of grapevine mildews, Pest Management Science, vol.71, pp.1247-1257, 2015.

D. H. Lorenz, Growth Stages of the Grapevine: Phenological growth stages of the grapevine (Vitis vinifera L. ssp. vinifera)-Codes and descriptions according to the extended BBCH scale ?, Australian Journal of Grape and Wine Research, vol.1, pp.100-103, 1995.

D. Gobbin, Importance of secondary inoculum of Plasmopara viticola to epidemics of grapevine downy mildew, Plant Pathology, vol.54, pp.522-534, 2005.

D. Gobbin, I. Pertot, and C. Gessler, Genetic structure of a Plasmopara viticola population in an isolated Italian mountain vineyard, Journal of Phytopathology, vol.151, pp.636-646, 2003.

C. B. Pereira, Temporal dynamics and management of downy mildew on the table grape 'BRS Vitória' in northern Paraná, Semina: Ciências Agrárias, vol.39, pp.19-28, 2018.

L. Michel, F. Brun, and D. Makowski, A framework based on generalised linear mixed models for analysing pest and disease surveys, Crop Protection, vol.94, pp.1-12, 2017.
URL : https://hal.archives-ouvertes.fr/hal-01530793

M. M. Kennelly, D. M. Gadoury, W. F. Wilcox, P. A. Magarey, and R. C. Seem, Primary infection, lesion productivity, and survival of sporangia in the grapevine downy mildew pathogen Plasmopara viticola, Phytopathology, vol.97, pp.512-522, 2007.

R. Rieder, W. Pavan, J. M. Carré-maciel, J. M. Cunha-fernandes, and M. Sarroglia-pinho, A virtual reality system to monitor and control diseases in strawberry with drones: a project. 7th Intl, Congress on Env. Modelling and Software, 2014.

L. D. Thiessen, Development of a grower-conducted inoculum detection assay for management of grape powdery mildew, Plant Pathology, vol.65, pp.238-249, 2016.

S. Dagostin, H. Schärer, I. Pertot, and L. Tamm, Are there alternatives to copper for controlling grapevine downy mildew in organic viticulture?, Crop Protection, vol.30, pp.776-788, 2011.

I. Pertot, A critical review of plant protection tools for reducing pesticide use on grapevine and new perspectives for the implementation of IPM in viticulture, Crop Protection, vol.97, pp.70-84, 2017.
URL : https://hal.archives-ouvertes.fr/hal-02628891

A. F. Espinoza, A. Hubert, Y. Raineau, C. Franc, and É. Giraud-héraud, Resistant grape varieties and market acceptance: an evaluation based on experimental economics, OENO One, vol.52, 2018.
URL : https://hal.archives-ouvertes.fr/hal-02621215

J. E. Oakley, SHELF: tools to support the Sheffield elicitation framework, 2018.

. R-core-team, R: A language and environment for statistical computing. The R Project for Statistical Computing

D. R. Cox, Regression models and life-tables, Journal of the Royal Statistical Society. Series B (Methodological), vol.34, pp.187-220, 1972.

D. E. Morris, J. E. Oakley, and J. A. Crowe, A web-based tool for eliciting probability distributions from experts, Environmental Modelling & Software, vol.52, pp.1-4, 2014.

. Anses.-e-phy, Le catalogue des produits phytopharmaceutiques et de leurs usages, des matières fertilisantes et des supports de culture autorisés en France, 2019.