GENEALOGIES OF TWO LINKED NEUTRAL LOCI AFTER A SELECTIVE SWEEP IN A LARGE POPULATION OF STOCHASTICALLY VARYING SIZE - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Accéder directement au contenu
Pré-Publication, Document De Travail Advances in Applied Probability Année : 2017

GENEALOGIES OF TWO LINKED NEUTRAL LOCI AFTER A SELECTIVE SWEEP IN A LARGE POPULATION OF STOCHASTICALLY VARYING SIZE

Résumé

We study the impact of a hard selective sweep on the genealogy of partially linked neutral loci in the vicinity of the positively selected allele. We consider a sexual population of stochastically varying size and, focusing on two neighboring loci, derive an approximate formula for the neutral genealogy of a sample of individuals taken at the end of the sweep. Individuals are characterized by ecological parameters depending on their genetic type and governing their growth rate and interactions with other individuals (competition). As a consequence, the "fitness" of an individual depends on the population state and is not an intrinsic characteristic of individuals. We provide a deep insight into the dynamics of the mutant and wild type populations during the different stages of a selective sweep.
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Dates et versions

hal-01116232 , version 1 (12-02-2015)
hal-01116232 , version 2 (17-02-2015)
hal-01116232 , version 3 (06-05-2016)

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Rebekka Brink-Spalink, Charline Smadi. GENEALOGIES OF TWO LINKED NEUTRAL LOCI AFTER A SELECTIVE SWEEP IN A LARGE POPULATION OF STOCHASTICALLY VARYING SIZE. 2016. ⟨hal-01116232v3⟩
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