Skip to Main content Skip to Navigation
Journal articles

Organ-wide and ploidy-dependent regulation both contribute to cell-size determination: evidence from a computational model of tomato fruit

Valentina Baldazzi 1, 2, 3 Pierre Valsesia 3 Michel Génard 3 Nadia Bertin 3
2 BIOCORE - Biological control of artificial ecosystems
CRISAM - Inria Sophia Antipolis - Méditerranée , INRA - Institut National de la Recherche Agronomique, LOV - Laboratoire d'océanographie de Villefranche
Abstract : The development of a new organ is the result of coordinated events of cell division and expansion, in strong interaction with each other. This study presents a dynamic model of tomato fruit development that includes cell division, endoreduplication, and expansion processes. The model is used to investigate the potential interactions among these developmental processes within the context of the neo-cellular theory. In particular, different control schemes (either cell-autonomous or organ-controlled) are tested and compared to experimental data from two contrasting genotypes. The model shows that a pure cell-autonomous control fails to reproduce the observed cell-size distribution, and that an organ-wide control is required in order to get realistic cell-size variations. The model also supports the role of endoreduplication as an important determinant of the final cell size and suggests that a direct effect of endoreduplication on cell expansion is needed in order to obtain a significant correlation between size and ploidy, as observed in real data.
Complete list of metadata

https://hal.inria.fr/hal-02407512
Contributor : Jean-Luc Gouzé <>
Submitted on : Thursday, April 15, 2021 - 2:09:05 PM
Last modification on : Thursday, June 24, 2021 - 12:09:59 PM
Long-term archiving on: : Friday, July 16, 2021 - 6:43:15 PM

File

erz398.pdf
Publisher files allowed on an open archive

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Citation

Valentina Baldazzi, Pierre Valsesia, Michel Génard, Nadia Bertin. Organ-wide and ploidy-dependent regulation both contribute to cell-size determination: evidence from a computational model of tomato fruit. Journal of Experimental Botany, Oxford University Press (OUP), 2019, 70 (21), pp.6215-6228. ⟨10.1101/450916⟩. ⟨hal-02407512⟩

Share

Metrics

Record views

167

Files downloads

141