The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA) - Innovations Thérapeutiques et Résistances
Journal Articles Environmental Health Perspectives Year : 2024

The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA)

1 Mizzou - University of Missouri [Columbia]
2 King's College London, School of Medicine
3 NC State - North Carolina State University [Raleigh]
4 Stockholm University
5 NIEHS-NIH - National Institute of Environmental Health Sciences [Durham, NC, USA]
6 Integrative Rheumatology Associates
7 CMU - Carnegie Mellon University [Pittsburgh]
8 PhyMA - Physiologie moléculaire et adaptation
9 Environmental Medicine Education International
10 UIUC - University of Illinois at Urbana-Champaign [Urbana]
11 ToxAlim - ToxAlim
12 California Pacific Medical Center Research Institute
13 University of Texas at Austin [Austin]
14 WSU - Washington State University
15 YCU - Yokohama City University
16 Wayne State University [Detroit]
17 Brunel University London [Uxbridge]
18 King's College London School of Medicine, King's College Hospital
19 FOOD PACKAGING FORUM FOUNDATION ZURICH CHE
20 Environmental Health Sciences
21 UMH - Universidad Miguel Hernández [Elche]
22 NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, USA
23 University of Michigan [Ann Arbor]
24 UNIPR - Università degli studi di Parma = University of Parma
25 UIC - University of Illinois [Chicago]
26 Thompson Center for Autism and Neurobehavioral Disorders
27 ITU - IT University of Copenhagen
28 Tufts University School of Medicine [Boston]
29 MSSM - Icahn School of Medicine at Mount Sinai [New York]
30 InTheRes - Innovations Thérapeutiques et Résistances
31 University of Arizona
32 UMass Amherst - University of Massachusetts [Amherst]
Frederick S Vom Saal
Ake Bergman
  • Function : Author
Veronique Gayrard
  • Function : Author
Zandra Palma
  • Function : Author
Lyn Patrick
  • Function : Author
Daniel Zalko
  • Function : Author

Abstract

The European Food Safety Authority (EFSA) recommended lowering their estimated tolerable daily intake (TDI) for bisphenol A (BPA) 20,000-fold to 0:2 ng=kg body weight ðBWÞ=day. BPA is an extensively studied high production volume endocrine disrupting chemical (EDC) associated with a vast array of diseases. Prior risk assessments of BPA by EFSA as well as the US Food and Drug Administration (FDA) have relied on industry-funded studies conducted under good laboratory practice protocols (GLP) requiring guideline end points and detailed record keeping,
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hal-04705628 , version 1 (23-09-2024)

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Frederick S Vom Saal, Michael Antoniou, Scott M Belcher, Ake Bergman, Ramji K Bhandari, et al.. The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA). Environmental Health Perspectives, 2024, 132 (4), ⟨10.1289/EHP13812⟩. ⟨hal-04705628⟩
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