Green optimization of the first steps for the synthesis of a novel surfactant: Towards the elimination of CMR Solvents and the drastic reduction of the used solvent volume - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
Article Dans Une Revue ChemistrySelect Année : 2019

Green optimization of the first steps for the synthesis of a novel surfactant: Towards the elimination of CMR Solvents and the drastic reduction of the used solvent volume

Christine Cecutti
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  • PersonId : 1206337
Sophie Thiebaud-Roux
Carlos Vaca Garcia
Emeline Vedrenne
  • Fonction : Auteur correspondant
  • PersonId : 1204398

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Résumé

In this report, the first steps of the synthesis of a novel surfactant have been described. Each stage has been optimized to abide by the principles of green chemistry. The replacement of CMR (Carcinogenic, Mutagenic, Reprotoxic) solvents by 4‐MTHP (4‐methyltetrahydropyran) led to the improvement of the overall yield and to the drastic reduction of the total organic solvent volume used in the process.

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Autre
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Dates et versions

hal-02618037 , version 1 (25-05-2020)

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Clément Giry, David Bertrand, Christine Cecutti, Clarisse Brossard, Ella Moreau, et al.. Green optimization of the first steps for the synthesis of a novel surfactant: Towards the elimination of CMR Solvents and the drastic reduction of the used solvent volume. ChemistrySelect, 2019, 4 (29), pp.8621-8625. ⟨10.1002/slct.201901876⟩. ⟨hal-02618037⟩
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