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Synchronized navigation and comparative analyses across Ensembl complete bacterial genomes with INSYGHT.

Thomas Lacroix 1, * Sylvie Thérond 2 Marc Rugeri 2 Pierre Nicolas 1 Annie Gendrault 1 Valentin Loux 1 Jean-François Gibrat 1
* Corresponding author
2 IDRIS
IDRIS - Institut du développement et des ressources en informatique scientifique
Abstract : Motivation: High-throughput sequencing technologies provide access to an increasing number of bacterial genomes. Today, many analyses involve the comparison of biological properties among many strains of a given species, or among species of a particular genus. Tools that can help the microbiologist with these tasks become increasingly important. Results: Insyght is a comparative visualization tool whose core features combine a synchronized navigation across genomic data of multiple organisms with a versatile interoperability between complementary views. In this work, we have greatly increased the scope of the Insyght public data- set by including 2688 complete bacterial genomes available in Ensembl thus vastly improving its phylogenetic coverage. We also report the development of a virtual machine that allows users to easily set up and customize their own local Insyght server.
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Submitted on : Wednesday, May 27, 2020 - 6:12:51 AM
Last modification on : Tuesday, June 22, 2021 - 11:18:09 AM

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Thomas Lacroix, Sylvie Thérond, Marc Rugeri, Pierre Nicolas, Annie Gendrault, et al.. Synchronized navigation and comparative analyses across Ensembl complete bacterial genomes with INSYGHT.. Bioinformatics, Oxford University Press (OUP), 2016, 32 (7), pp.1083-1084. ⟨10.1093/bioinformatics/btv689⟩. ⟨hal-02630699⟩

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