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Syndrome métabolique : une histoire d'empreinte nutritionnelle et d'épigénétique ?

Abstract : The concept of metabolic imprinting developed from the observation of a relationship between perinatal growth rate and the risk of late onset metabolic disease. According to this concept, early nutrition could influence a number of key metabolic pathways in the long term, and this influence could even be in some way transmitted to future generations. As demonstrated in animal models, nutrients could act on secondary genomic structure and expression through epigenetic mechanisms. Further studies of human populations are needed to confirm this hypothesis.
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https://hal.inrae.fr/hal-02657573
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Submitted on : Saturday, May 30, 2020 - 10:48:24 AM
Last modification on : Monday, August 16, 2021 - 1:58:03 PM

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Patricia Parnet, Francisco Bolaños-Jiménez, Valérie Amarger. Syndrome métabolique : une histoire d'empreinte nutritionnelle et d'épigénétique ?. Obésité, Springer Verlag, 2007, 2, pp.158-165. ⟨10.1007/s11690-007-0048-6⟩. ⟨hal-02657573⟩

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