Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
Article Dans Une Revue Animal Biotechnology Année : 2009

Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism

Résumé

The growth hormone secretagogue receptor (GHSR) is involved in the regulation of energetic homeostasis and GH secretion. In this study, the bovine GHSR gene was mapped to BTA1 between BL26 and BMS4004. Two different bovine GHSR CDS (GHSR1a and GHSR1b) were sequenced. Six polymorphisms (five SNPs and one 3-bp indel) were also identified, three of them leading to amino acid variations L24V, D194N, and Del R242. These variations are located in the extracellular N-terminal end, the exoloop 2, and the cytoloop 3 of the receptor, respectively.

Dates et versions

hal-02664810 , version 1 (31-05-2020)

Identifiants

Citer

F.G. Colinet, S. Vanderick, B. Charloteaux, Andre A. Eggen, N. Gengler, et al.. Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism. Animal Biotechnology, 2009, 20 (1), pp.28-33. ⟨10.1080/10495390802602926⟩. ⟨hal-02664810⟩
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