Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

Abstract : Abdominal pain is common in the general population and, in patients with irritable bowel syndrome, is attributed to visceral hypersensitivity. We found that oral administration of specific Lactobacillus strains induced the expression of mu-opioid and cannabinoid receptors in intestinal epithelial cells, and mediated analgesic functions in the gut-similar to the effects of morphine. These results suggest that the microbiology of the intestinal tract influences our visceral perception, and suggest new approaches for the treament of abdominal pain and irritable bowel syndrome.
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal.inrae.fr/hal-02667010
Déposant : Migration Prodinra <>
Soumis le : dimanche 31 mai 2020 - 09:52:14
Dernière modification le : lundi 6 juillet 2020 - 10:18:02

Identifiants

Collections

Citation

Christel Rousseaux, Xavier Thuru, Agathe Gelot, Nicolas Barnich, Christel Neut, et al.. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nature Medicine, Nature Publishing Group, 2007, 13 (1), pp.35-37. ⟨10.1038/nm1521⟩. ⟨hal-02667010⟩

Partager

Métriques

Consultations de la notice

10